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The DOI matches its Crossref record; 105 of the 105 references it cites were found in a registry or an index.

Cell-PLoc 2.0: an improved package of web-servers for predicting subcellular localization of proteins in various organisms

Open access
Chou, Kuo-Chen, Shen, Hong-Bin·2010·Natural Science

Abstract

Cell-PLoc 2.0 is a package of web-servers evolved from Cell-PLoc (Chou, K.C. & Shen, H.B., Nature Protocols, 2008, 2:153-162) by a top-down approach to improve the power for predicting subcellular localization of proteins in various organisms. It contains six predictors: Euk-mPLoc 2.0, Hum-mPLoc 2.0, Plant-mPLoc, Gpos-mPLoc, Gneg-mPLoc, and Virus-mPLoc, specialized for eukaryotic, human, plant, Gram- positive bacterial, Gram-negative bacterial, and virus proteins, respectively. Compared with Cell-PLoc, the predictors in the Cell-PLoc 2.0 have the following advantageous features: (1) they all have the capacity to deal with the multiplex proteins that can simultaneiously exist, or move between, two or more subcellular location sites; (2) no accession number is needed for the input of a query protein even if using the “high- level” GO (gene ontology) prediction engine; (3) the functional domain information and sequential evolution information are fused into the “ab initio” sequence-based prediction engine to enhance its accuracy. In this protocol, a step- to-step guide is provided for how to use the web server predictors in the Cell-PLoc 2.0 package, which is freely accessible to the public at http://www.csbio.sjtu.edu.cn/bioinf/Cell-PLoc-2/.

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Metadata

Authors
Chou, K.-C., & Shen, H.-B.
Venue
Natural Science
Published
2010
Volume
02
Issue
10
Pages
1090-1103
ISSN
  • 2150-4091 (ISSN-L)
  • 2150-4105
OpenAlex
W1970399546
Cited by
347
References
105
FWCI
11.11
Type
journal article
Language
en
Open access
hybrid

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CoChat. (2026). Citation check: Cell-PLoc 2.0: an improved package of web-servers for predicting subcellular localization of proteins in various organisms. https://app.cochat.ai/papers/10.4236/ns.2010.210136
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Chou, K.-C., & Shen, H.-B. (2010). Cell-PLoc 2.0: an improved package of web-servers for predicting subcellular localization of proteins in various organisms. Natural Science. https://doi.org/10.4236/ns.2010.210136

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