The DOI matches its Crossref record; 60 of the 60 references it cites were found in a registry or an index.
Risk of stroke after transcatheter aortic valve implantation (TAVI): a meta-analysis of 10,037 published patients
Abstract
AIMS: Transcatheter aortic valve implantation (TAVI) represents a novel treatment option for inoperable or high surgical risk patients with severe symptomatic aortic valve disease. Recent randomised studies have raised major safety concerns because of increased stroke/transient ischemic attack (TIA) rates with TAVI compared to medical treatment and conventional aortic valve replacement. We aimed to review all currently published literature and estimate the incidence of periprocedural stroke and outcomes in patients undergoing TAVI. METHODS AND RESULTS: Fifty-three studies including a total of 10,037 patients undergoing transfemoral, transapical or trans-subclavian TAVI for native aortic valve stenosis published between 01/2004 and 11/2011 were identified and included in a meta-analysis. Patients were 81.5 ± 1.8-years-old and had a mean logistic EuroSCORE of 24.77 ± 5.60%. Procedural stroke (<24 h) occurred in 1.5 ± 1.4%. The overall 30-day stroke/TIA was 3.3 ± 1.8%, with the majority being major strokes (2.9 ± 1.8%). During the first year after TAVI, stroke/TIA increased up to 5.2 ± 3.4%. Differences in stroke rates were associated with different approaches and valve prostheses used with lowest stroke rates after transapical TAVI (2.7 ± 1.4%). Average 30-day mortality was more than 3.5-fold higher in patients with compared to those without stroke (25.5 ± 21.9% vs. 6.9 ± 4.2%). CONCLUSIONS: TAVI was associated with average 30-day stroke/TIA rate of 3.3 ± 1.8% (range 0-6%). Most of these strokes were major strokes and were associated with increased mortality within in the first 30 days.
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Cites
Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who Cannot Undergo Surgery
Leon, M. B., Smith, C. R., Mack, M., Miller, D. C., Moses, J. W., Svensson, L. G., Tuzcu, E. M., Webb, J. G., Fontana, G. P., Makkar, R. R., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1008232 · Cited by 7,205
Transcatheter versus Surgical Aortic-Valve Replacement in High-Risk Patients
Smith, C. R., Leon, M. B., Mack, M. J., Miller, D. C., Moses, J. W., Svensson, L. G., Tuzcu, E. M., Webb, J. G., Fontana, G. P., Makkar, R. R., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1103510 · Cited by 6,345
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Self-citationTreatment of Calcific Aortic Stenosis With the Percutaneous Heart Valve
Cribier, A., Eltchaninoff, H., Tron, C., Bauer, F., Agatiello, C., Nercolini, D., Tapiero, S., Litzler, P.-Y., Bessou, J.-P., & Babaliaros, V. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.01.049 · Cited by 715
Cited by
Erbel (2014) · doi:10.1093/eurheartj/ehu281 · Cited by 4,451
2014 ESC Guidelines on the diagnosis and treatment of aortic diseases
Erbel, R., Aboyans, V., Boileau, C., Bossone, E., Di Bartolomeo, R., Eggebrecht, H., Evangelista, A., Falk, V., Frank, H., Gaemperli, O., et al. (2014) · Kardiologia Polska · doi:10.5603/kp.2014.0225 · Cited by 458
Self-citationNombela-Franco, L., Webb, J. G., de Jaegere, P. P., Toggweiler, S., Nuis, R.-J., Dager, A. E., Amat-Santos, I. J., Cheung, A., Ye, J., Binder, R. K., et al. (2012) · Circulation · doi:10.1161/circulationaha.112.110981 · Cited by 422
Metadata
- Authors
- Eggebrecht, H., Schmermund, A., Voigtländer, T., Kahlert, P., Erbel, R., & Mehta, R. H.
- Venue
- EuroIntervention
- Publisher
- Europa Digital & Publishing
- Published
- 2012-05
- Volume
- 8
- Issue
- 1
- Pages
- 129-138
- ISSN
- 1774-024X (ISSN-L)
- OpenAlex
- W2086960806
- Cited by
- 406
- References
- 60
- FWCI
- 8.89
- Type
- journal article
- Language
- en
- Open access
- closed
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- Eggebrecht, H., Schmermund, A., Voigtländer, T., Kahlert, P., Erbel, R., & Mehta, R. H. (2012). Risk of stroke after transcatheter aortic valve implantation (TAVI): a meta-analysis of 10,037 published patients. EuroIntervention. https://doi.org/10.4244/eijv8i1a20
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