The DOI matches its Crossref record; 17 of the 17 references it cites were found in a registry or an index.
Global Epidemiology of Plasmodium vivax
Open accessAbstract
Plasmodium vivax is the most widespread human malaria, putting 2.5 billion people at risk of infection. Its unique biological and epidemiological characteristics pose challenges to control strategies that have been principally targeted against Plasmodium falciparum Unlike P. falciparum, P. vivax infections have typically low blood-stage parasitemia with gametocytes emerging before illness manifests, and dormant liver stages causing relapses. These traits affect both its geographic distribution and transmission patterns. Asymptomatic infections, high-risk groups, and resulting case burdens are described in this review. Despite relatively low prevalence measurements and parasitemia levels, along with high proportions of asymptomatic cases, this parasite is not benign. Plasmodium vivax can be associated with severe and even fatal illness. Spreading resistance to chloroquine against the acute attack, and the operational inadequacy of primaquine against the multiple attacks of relapse, exacerbates the risk of poor outcomes among the tens of millions suffering from infection each year. Without strategies accounting for these P. vivax-specific characteristics, progress toward elimination of endemic malaria transmission will be substantially impeded.
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Cited by
Plasmodium vivax in the Era of the Shrinking P. falciparum Map
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Self-citationEpidemiology, drug resistance, and pathophysiology of Plasmodium vivax malaria
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Watson, J., Taylor, W. R. J., Bancone, G., Chu, C. S., Jittamala, P., & White, N. J. (2018) · PLOS Neglected Tropical Diseases · doi:10.1371/journal.pntd.0006440 · Cited by 77
Metadata
- Authors
- Howes, R. E., Battle, K. E., Mendis, K. N., Smith, D. L., Cibulskis, R. E., Baird, J. K., & Hay, S. I.
- Venue
- The American Journal of Tropical Medicine and Hygiene
- Published
- 2016-07-11
- Volume
- 95
- Issue
- 6 Suppl
- Pages
- 15-34
- ISSN
- 0002-9637 (ISSN-L)
- 1476-1645
- OpenAlex
- W2462041221
- Cited by
- 418
- References
- 17
- FWCI
- 37.18
- Type
- journal article
- Language
- en
- Open access
- green
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- Howes, R. E., Battle, K. E., Mendis, K. N., Smith, D. L., Cibulskis, R. E., Baird, J. K., & Hay, S. I. (2016). Global Epidemiology of Plasmodium vivax. The American Journal of Tropical Medicine and Hygiene. https://doi.org/10.4269/ajtmh.16-0141
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