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Lassa Fever, a New Virus Disease of Man from West Africa: I. Clinical Description and Pathological Findings
Abstract
Lassa Fever, a hitherto unknown virus disease from Nigeria, caused the death of two missionary-nurses and the grave illness of a third. The onset is gradual with fever, weakness, myositis and ulcerative pharyngitis, progressing to symptoms of myocarditis, pneumonitis and pleuritis, encephalopathy, and evidences of a hemorrhagic diathesis. It is characterized in the early stages by moderate leukopenia, with increase of immature neutrophilic elements. It may be transmitted directly from person to person; the incubation period is about a week. It is likely to be of increasing public-health importance as travel to the interior parts of Nigeria increases, and as the area is developed because of future population pressures.
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Citations
Cited by
A Case-Control Study of the Clinical Diagnosis and Course of Lassa Fever
McCormick, J. B., King, I. J., Webb, P. A., Johnson, K. M., O'Sullivan, R., Smith, E. S., Trippel, S., & Tong, T. C. (1987) · Journal of Infectious Diseases · doi:10.1093/infdis/155.3.445 · Cited by 409
Lassa Virus Isolation from Mastomys natalensis Rodents during an Epidemic in Sierra Leone
Monath, T. P., Newhouse, V. F., Kemp, G. E., Setzer, H. W., & Cacciapuoti, A. (1974) · Science · doi:10.1126/science.185.4147.263 · Cited by 329
Fever, fever patterns and diseases called “fever”—A review
Ogoina, D. (2011) · Journal of Infection and Public Health · doi:10.1016/j.jiph.2011.05.002 · Cited by 305
COVID-19 vaccines: breaking record times to first-in-human trials
Kim, Y. C., Dema, B., & Reyes-Sandoval, A. (2020) · npj Vaccines · doi:10.1038/s41541-020-0188-3 · Cited by 117
Bonner, P. C., Schmidt, W.-P., Belmain, S. R., Oshin, B., Baglole, D., & Borchert, M. (2007) · The American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2007.77.169 · Cited by 104
Metadata
- Authors
- Frame, J. D., Baldwin, J. M., Gocke, D. J., & Troup, J. M.
- Venue
- The American Journal of Tropical Medicine and Hygiene
- Published
- 1970-07
- Volume
- 19
- Issue
- 4
- Pages
- 670-676
- ISSN
- 0002-9637 (ISSN-L)
- OpenAlex
- W1509033271
- Cited by
- 536
- References
- 0
- FWCI
- 22.32
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Lassa Fever, a New Virus Disease of Man from West Africa: I. Clinical Description and Pathological Findings. https://app.cochat.ai/papers/10.4269/ajtmh.1970.19.670
- The paper
- Frame, J. D., Baldwin, J. M., Gocke, D. J., & Troup, J. M. (1970). Lassa Fever, a New Virus Disease of Man from West Africa: I. Clinical Description and Pathological Findings. The American Journal of Tropical Medicine and Hygiene. https://doi.org/10.4269/ajtmh.1970.19.670
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
