Fever, fever patterns and diseases called “fever”—A review
Open accessAbstract
Fever is a prominent feature of disease since antiquity. The febrile response is orchestrated by the central nervous system through endocrine, neurological, immunological and behavioural mechanisms. Other than a regulated rise in body temperature, fever is often accompanied by various sickness behaviours, changes in metabolic and physiological characteristics of body systems and alterations in immune responses. Fever and the febrile response, therefore, remain significant contributors to the pathogenesis, clinical presentation and outcome of many illnesses and diseases. This review highlights the pathophysiology of the febrile response and describes the fever types and patterns, including their clinical significance. The various medical illnesses called "fever" are also listed and the origins of their appellations discussed.
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Internal body temperature differs from peripheral body temperature such as that of limbs.
“Internal body temperature is different from the body temperature of peripherals such as limbs, and the boundary between them is indeterminate and varies with ambient temperature [134].”
From The Current State of Optical Sensors in Medical Wearables (2022) · cites this paper as [134]
Continuous measurement of core body temperature can determine the patient's circadian cycle.
“From continuous measurements of core body temperature, we can determine the circadian cycle of the patient.”
From The Current State of Optical Sensors in Medical Wearables (2022) · cites this paper as [134]
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- Authors
- Ogoina, D.
- Affiliations
- Bingham University (NG)
- Corresponding author
- Ogoina, Dimie
- ORCID
- Ogoina, Dimie
- Venue
- Journal of Infection and Public Health
- Publisher
- Elsevier BV
- Published
- 2011-08
- Volume
- 4
- Issue
- 3
- Pages
- 108-124
- ISSN
- 1876-0341 (ISSN-L)
- OpenAlex
- W2012679426
- Cited by
- 305
- References
- 62
- Citations by year
- 2026: 17 · 2025: 21 · 2024: 38 · 2023: 52 · 2022: 39 · 2021: 48 · 2020: 25 · 2019: 25 · 2018: 7 · 2017: 6 · 2016: 8 · 2015: 4 · 2014: 5 · 2013: 7 · 2012: 3
- FWCI
- 0.72
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Infection and Public Health (publishedVersion)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Critical Care and Intensive Care Medicine › Thermal Regulation in Medicine
- Health Sciences › Medicine › Physiology › Thermoregulation and physiological responses
- Health Sciences › Medicine › Epidemiology › Sepsis Diagnosis and Treatment
- Keywords
- fever, febrile response, fever patterns, fever pathophysiology, sickness behavior, immune response, thermoregulation
- MeSH terms
- Communicable Diseases, Fever, Humans
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