The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
SEROTYPE-SPECIFIC DIFFERENCES IN CLINICAL MANIFESTATIONS OF DENGUE
Abstract
Dengue, the most prevalent arthropod-borne viral disease of humans, is caused by four serotypes of dengue virus (DENV 1–4). Although all four DENV serotypes cause a range of illness, defining precisely which clinical characteristics are associated with the distinct serotypes has been elusive. A cross-sectional study was conducted on 984 and 313 hospitalized children with confirmed DENV infections during two time periods, respectively, in the same hospitals in Nicaragua: a 3-year period (1999–2001) when DENV-2 accounted for 96% of the viruses identified, and the 2003 dengue season when DENV-1 predominated (87% of identified serotypes). When the two periods were compared, more shock (OR 1.91, 95% CI 1.35–2.71) and internal hemorrhage (OR 2.05, CI 1.16–3.78) were observed in the period when DENV-2 predominated, whereas increased vascular permeability was associated to a greater degree with the DENV-1 period (OR 2.36, CI 1.80–3.09). Compared with the DENV-2 period, the DENV-1 season was associated with more hospitalized primary dengue cases (OR 3.86, CI 2.72–5.48) and more primary DENV infections with severe manifestations (OR 2.93, CI 2.00–4.28). These findings provide new data to characterize the pathogenic potential of distinct DENV serotypes in human populations.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Dengue and Dengue Hemorrhagic Fever
Gubler, D. J. (1998) · Clinical Microbiology Reviews · doi:10.1128/cmr.11.3.480 · Cited by 4,310
Lanciotti, R. S., Calisher, C. H., Gubler, D. J., Chang, G. J., & Vorndam, A. V. (1992) · Journal of Clinical Microbiology · doi:10.1128/jcm.30.3.545-551.1992 · Cited by 1,818
Dengue Viremia Titer, Antibody Response Pattern, and Virus Serotype Correlate with Disease Severity
Vaughn, D. W., Green, S., Kalayanarooj, S., Innis, B. L., Nimmannitya, S., Suntayakorn, S., Endy, T. P., Raengsakulrach, B., Rothman, A. L., Ennis, F. A., et al. (2000) · The Journal of Infectious Diseases · doi:10.1086/315215 · Cited by 1,632
Guzmán, M. G., & Kouri, G. (2002) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(01)00171-2 · Cited by 1,163
Gibbons, R. V., & Vaughn, D. W. (2002) · BMJ · doi:10.1136/bmj.324.7353.1563 · Cited by 783
Dengue: the risk to developed and developing countries.
Monath, T. P. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.7.2395 · Cited by 779
Dengue haemorrhagic fever: diagnosis, treatment, prevention and control
Crane, G. (1999) · Pathology · doi:10.1016/s0031-3025(16)34854-1 · Cited by 744
RISK FACTORS IN DENGUE SHOCK SYNDROME: A PROSPECTIVE EPIDEMIOLOGIC STUDY IN RAYONG, THAILAND
SANGKAWIBHA, N., ROJANASUPHOT, S., AHANDRIK, S., VIRIYAPONGSE, S., JATANASEN, S., SALITUL, V., PHANTHUMACHINDA, B., & HALSTEAD, S. B. (1984) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a113932 · Cited by 716
Origins of Dengue Type 2 Viruses Associated with Increased Pathogenicity in the Americas
Rico-Hesse, R., Harrison, L. M., Salas, R. A., Tovar, D., Nisalak, A., Ramos, C., Boshell, J., de Mesa, M. T. R., Nogueira, R. M. R., & Rosa, A. T. D. (1997) · Virology · doi:10.1006/viro.1997.8504 · Cited by 681
Emergence and Global Spread of a Dengue Serotype 3, Subtype III Virus
Messer, W. B., Gubler, D. J., Harris, E., Sivananthan, K., & de Silva, A. M. (2003) · Emerging Infectious Diseases · doi:10.3201/eid0907.030038 · Cited by 445
Self-citation
Cited by
Global Spread and Persistence of Dengue
Kyle, J. L., & Harris, E. (2008) · Annual Review of Microbiology · doi:10.1146/annurev.micro.62.081307.163005 · Cited by 916
Self-citationCross-serotype interactions and disease outcome prediction of dengue infections in Vietnam
Aguas, R., Dorigatti, I., Coudeville, L., Luxemburger, C., & Ferguson, N. M. (2019) · Scientific Reports · doi:10.1038/s41598-019-45816-6 · Cited by 207
The role and function of Fcγ receptors on myeloid cells
Bournazos, S., Wang, T. T., & Ravetch, J. V. (2016) · Microbiology Spectrum · doi:10.1128/microbiolspec.mchd-0045-2016 · Cited by 138
Metadata
- Authors
- BALMASEDA, A., HAMMOND, S. N., PÉREZ, L., TELLEZ, Y., SABORÍO, S. I., MERCADO, J. C., CUADRA, R., ROCHA, J., PÉREZ, M. A., SILVA, S., ROCHA, C., & HARRIS, E.
- Venue
- The American Journal of Tropical Medicine and Hygiene
- Published
- 2006-03
- Volume
- 74
- Issue
- 3
- Pages
- 449-456
- ISSN
- 0002-9637 (ISSN-L)
- OpenAlex
- W2122917913
- Cited by
- 299
- References
- 26
- FWCI
- 8.39
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: SEROTYPE-SPECIFIC DIFFERENCES IN CLINICAL MANIFESTATIONS OF DENGUE. https://app.cochat.ai/papers/10.4269/ajtmh.2006.74.449
- The paper
- BALMASEDA, A., HAMMOND, S. N., PÉREZ, L., TELLEZ, Y., SABORÍO, S. I., MERCADO, J. C., CUADRA, R., ROCHA, J., PÉREZ, M. A., SILVA, S., ROCHA, C., & HARRIS, E. (2006). SEROTYPE-SPECIFIC DIFFERENCES IN CLINICAL MANIFESTATIONS OF DENGUE. The American Journal of Tropical Medicine and Hygiene. https://doi.org/10.4269/ajtmh.2006.74.449
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
