The DOI matches its Crossref record.
Inhibition of Amino Acid Decarboxylase Activity of Enterobacter aerogenes by Active Components in Spices
Open accessAbstract
The water and ethanol extracts of several commercially available spices were examined for their inhibitory action on the decarboxylase activity of a crude extract of Enterobacter aerogenes . The water extracts had a negligible effect on histidine decarboxylase activity, except for water extract of cloves which reduced the activity by about 40%. However, the ethanol extracts had a rather higher inhibitory action upon histidine, lysine, and ornithine decarboxylases. Of the spices used, cloves, cinnamon, sage, nutmeg, and allspice were very effective in inhibiting the decarboxylases. Among the components of those spices, cinnamaldehyde and eugenol were found to be effective inhibitors.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Cinnamaldehyde is indeed capable of altering the lipid profile of the microbial cell membrane [47].”
From Effect of essential oils on pathogenic bacteria (2013) · cites this paper as [47]
In the citing paper
“It also acts against different bacterial enzymes, including ATPase, histidine carboxylase, amylase and protease [46,47].”
From Effect of essential oils on pathogenic bacteria (2013) · cites this paper as [47]
In the citing paper
“Non-specific inhibition of membrane-bound or -embedded enzymes can be caused by small hydrophobic molecules as a result of changes in the protein conformation.”
From Effect of essential oils on pathogenic bacteria (2013) · cites this paper as [47]
Citations
Cited by
Sorted by citations
Essential oils: Their antibacterial properties and potential applications in foods—A review
Burt, S. (2004) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2004.03.022 · Cited by 10,488
“The hydroxyl group on eugenol is thought to bind to proteins, preventing enzyme action in E. aerogenes (Wendakoon and Sakaguchi, 1995).”
BackgroundInfluentialHyldgaard, M., Mygind, T., & Meyer, R. L. (2012) · Frontiers in Microbiology · doi:10.3389/fmicb.2012.00012 · Cited by 2,191
“, the histidine decarboxylase, is also inhibited by cinnamaldehyde (Wendakoon and Morihiko, 1995).”
BackgroundEffect of essential oils on pathogenic bacteria
Nazzaro, F., Fratianni, F., De Martino, L., Coppola, R., & De Feo, V. (2013) · Pharmaceuticals · doi:10.3390/ph6121451 · Cited by 2,186
“Cinnamaldehyde is indeed capable of altering the lipid profile of the microbial cell membrane [47].”
BackgroundEdris, A. E. (2007) · Phytotherapy Research · doi:10.1002/ptr.2072 · Cited by 1,264
“Impairment of bacterial enzyme systems may also be a potential mechanism of action (Wendakoon and Sakaguchi, 1995).”
BackgroundInvited review: essential oils as modifiers of rumen microbial fermentation
Calsamiglia, S., Busquet, M., Cardozo, P. W., Castillejos, L., & Ferret, A. (2007) · Journal of Dairy Science · doi:10.3168/jds.2006-644 · Cited by 1,014
“The antimicrobial activity of cinnamaldehyde is likely related to the reactivity of its carbonyl group (Wendakoon and Sakaguchi, 1995; Helander et al., 1998), but the exact mechanism of action is not known.”
Background
Metadata
- Authors
- Wendakoon, C. N., & Sakaguchi, M.
- Affiliations
- Kyoto University (JP)
- Venue
- Journal of Food Protection
- Publisher
- Elsevier BV
- Published
- 1995-03
- Volume
- 58
- Issue
- 3
- Pages
- 280-283
- ISSN
- 0362-028X (ISSN-L)
- OpenAlex
- W2409189647
- Cited by
- 377
- References
- 0
- Citations by year
- 2026: 2 · 2025: 7 · 2024: 15 · 2023: 17 · 2022: 14 · 2021: 14 · 2020: 18 · 2019: 16 · 2018: 16 · 2017: 16 · 2016: 24 · 2015: 23 · 2014: 18 · 2013: 28 · 2012: 27
- FWCI
- 0.12
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Food Protection (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Polyamine Metabolism and Applications
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Antimicrobial agents and applications
- Keywords
- Enterobacter aerogenes, spices, histidine decarboxylase, lysine decarboxylase, ornithine decarboxylase, cinnamaldehyde, eugenol, Syzygium aromaticum, cinnamon, nutmeg, allspice, sage, antimicrobial food additives
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
