The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Astaxanthin in microalgae: pathways, functions and biotechnological implications
Open accessAbstract
Major progress has been made in the past decade towards understanding of the biosynthesis of red carotenoid astax-anthin and its roles in stress response while exploiting microalgae-based astaxanthin as a potent antioxidant for hu-man health and as a coloring agent for aquaculture applications. In this review, astaxanthin-producing green microal-gae are briefly summarized with Haematococcus pluvialis and Chlorella zofingiensis recognized to be the most popular astaxanthin-producers. Two distinct pathways for astaxanthin synthesis along with associated cellular, physiological, and biochemical changes are elucidated using H. pluvialis and C. zofingiensis as the model systems. Interactions between astaxanthin biosynthesis and photosynthesis, fatty acid biosynthesis and enzymatic defense systems are described in the context of multiple lines of defense mechanisms working in concert against photooxidative stress. Major pros and cons of mass cultivation of H. pluvialis and C. zofingiensis in phototrophic, heterotrophic, and mixotrophic culture modes are analyzed. Recent progress in genetic engineering of plants and microalgae for astaxanthin production is presented. Future advancement in microalgal astaxanthin research will depend largely on genome sequencing of H. pluvialis and C. zofingiensis and genetic toolbox development. Continuous effort along the heterotrophic-phototrophic culture mode could lead to major expansion of the microalgal astaxanthin industry.
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Cites
Secondary ketocarotenoid astaxanthin biosynthesis in algae: a multifunctional response to stress
Lemoine, Y., & Schoefs, B. (2010) · Photosynthesis Research · doi:10.1007/s11120-010-9583-3 · Cited by 384
Production of astaxanthin by the green microalga Chlorella zofingiensis in the dark
Ip, P.-F., & Chen, F. (2005) · Process Biochemistry · doi:10.1016/j.procbio.2004.01.039 · Cited by 270
Boussiba, S., Bing, W., Yuan, J.-P., Zarka, A., & Chen, F. (1999) · Biotechnology Letters · doi:10.1023/a:1005507514694 · Cited by 247
Ip, P.-F., Wong, K.-H., & Chen, F. (2004) · Process Biochemistry · doi:10.1016/j.procbio.2003.08.003 · Cited by 184
Grünewald, K., Hirschberg, J., & Hagen, C. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m006400200 · Cited by 175
Cited by
Microalgal Carotenoids: A Review of Production, Current Markets, Regulations, and Future Direction
Novoveská, L., Ross, M. E., Stanley, M. S., Pradelles, R., Wasiolek, V., & Sassi, J.-F. (2019) · Marine Drugs · doi:10.3390/md17110640 · Cited by 462
Minhas, A. K., Hodgson, P., Barrow, C. J., & Adholeya, A. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00546 · Cited by 445
Carotenoids from Marine Microalgae: A Valuable Natural Source for the Prevention of Chronic Diseases
Raposo, M., De Morais, A., & De Morais, R. (2015) · Marine Drugs · doi:10.3390/md13085128 · Cited by 228
Garrido-Cardenas, J. A., Manzano-Agugliaro, F., Acien-Fernandez, F. G., & Molina-Grima, E. (2018) · Algal Research · doi:10.1016/j.algal.2018.08.005 · Cited by 216
Oslan, S. N. H., Shoparwe, N. F., Yusoff, A. H., Rahim, A. A., Chang, C. S., Tan, J. S., Oslan, S. N., Arumugam, K., Ariff, A. B., Sulaiman, A. Z., et al. (2021) · Biomolecules · doi:10.3390/biom11020256 · Cited by 215
Metadata
- Authors
- Han, D., Li, Y., & Hu, Q.
- Venue
- ALGAE
- Publisher
- The Korean Society of Phycology
- Published
- 2013-06-15
- Volume
- 28
- Issue
- 2
- Pages
- 131-147
- ISSN
- 1226-2617 (ISSN-L)
- OpenAlex
- W2095891925
- Cited by
- 261
- References
- 5
- FWCI
- 3.61
- Type
- journal article
- Language
- en
- Open access
- green
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