Multiple sclerosis: patient-reported quality of life in the Świętokrzyskie region
Open accessAbstract
Wprowadzenie: Sytuacja epidemiologiczna i jakość życia chorych ze stwardnieniem rozsianym w Polsce są niedostatecznie rozpoznane. Cel pracy: Analiza samooceny dotyczącej jakości życia oraz wybranych parametrów klinicznych i socjodemograficznych pacjentów ze stwardnieniem rozsianym zarejestrowanych w Kohorcie Świętokrzyskiej Polskiego Rejestru Chorych ze Stwardnieniem Rozsianym (RejSM). Materiał i metody: W badaniu wzięli udział chorzy zamieszkujący województwo świętokrzyskie, a dane zbierano między 1 stycznia 2014 r. a 31 grudnia 2015 r. poprzez portal internetowy RejSM. Pacjenci po zarejestrowaniu przez lekarza samodzielnie oceniali jakość życia za pomocą polskich wersji kwestionariuszy samooceny EuroQol (EQ-5D i EQ-VAS) oraz Multiple Sclerosis Impact Scale (MSIS-29). Wyniki: Spośród 1525 zarejestrowanych pacjentów do badania włączono 765 osób, które zgodziły się na samoocenę jakości życia. Średni indeks EQ-5D wynosił 0,78 ±0,28, a średni wynik w EQ-VAS 65,6 ±23,8. Ocena za pomocą MSIS-29 dała średni wynik 86,4 ±22,4 (dla stanu fizycznego 64,2 ±19,6 i dla stanu psychicznego 24,7 ±7,8). Jedynie 34,7% chorych było aktywnych zawodowo. Niższa jakość życia była istotnie związana z wyższym poziomem niesprawności (p < 0,001), wiekiem powyżej 40 lat (p < 0,001), dłuższym czasem trwania choroby (p < 0,001), brakiem dostępu do leczenia (p < 0,001) i brakiem zatrudnienia (p = 0,002). Nie stwierdzono zależności między jakością życia a płcią, przebiegiem choroby, wykształceniem, miejscem zamieszkania i stanem rodzinnym. Wnioski: Na obniżenie jakości życia chorych ze stwardnieniem rozsianym z regionu świętokrzyskiego wpływa przede wszystkim zaawansowana niesprawność, starszy wiek, długi czas trwania choroby oraz ograniczony dostęp do pracy i leczenia immunomodulującego.
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Functional impairment as assessed by the Expanded Disability Status Scale level was one of the leading causes of diminished quality of life in multiple sclerosis.
“Functional impairment as assessed by the Expanded Disability Status Scale (EDSS) level was one of the leading causes of diminished QoL.25–35”
From Quality of life in adults with multiple sclerosis: A systematic review (2020) · cites this paper as [30]
Disease duration is a relevant factor negatively affecting quality of life in multiple sclerosis.
“Disease duration,30 31 progressive type,26 36 37 progressive MS onset38 and relapses in the last 3 months were further relevant factors negatively affecting QoL.26”
From Quality of life in adults with multiple sclerosis: A systematic review (2020) · cites this paper as [30]
Unemployment is associated with lower quality of life in multiple sclerosis.
“Several studies displayed an association between unemployment and lower QoL.30 34 54 67 94”
From Quality of life in adults with multiple sclerosis: A systematic review (2020) · cites this paper as [30]
The Expanded Disability Status Scale was most employed for assessment of functional impairment.
“The results showed that the EDSS was most employed for assessment of functional impairment.25–35”
From Quality of life in adults with multiple sclerosis: A systematic review (2020) · cites this paper as [30]
Lack of access to therapy was identified as a risk factor for quality of life in multiple sclerosis.
“In keeping with the negative influence of the scarcity of resources, lack of access to therapy was also identified as a risk factor.30 31”
From Quality of life in adults with multiple sclerosis: A systematic review (2020) · cites this paper as [30]
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Cites
Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria
Polman, C. H., Reingold, S. C., Banwell, B., Clanet, M., Cohen, J. A., Filippi, M., Fujihara, K., Havrdova, E., Hutchinson, M., Kappos, L., et al. (2011) · Annals of Neurology · doi:10.1002/ana.22366 · Cited by 9,802 · see citing works
The Multiple Sclerosis Impact Scale (MSIS-29): A new patient-based outcome measure
Hobart, J. (2001) · Brain · doi:10.1093/brain/124.5.962 · Cited by 1,120 · see citing works
Incidence and prevalence of multiple sclerosis in Europe: a systematic review
Kingwell, E., Marriott, J. J., Jetté, N., Pringsheim, T. M., Makhani, N., Morrow, S. A., Fisk, J. D., Evans, C. D., Béland, S. G., Kulaga, S., et al. (2013) · BMC Neurology · doi:10.1186/1471-2377-13-128 · Cited by 520 · see citing works
Lobentanz, I. S., Asenbaum, S., Vass, K., Sauter, C., Klosch, G., Kollegger, H., Kristoferitsch, W., & Zeitlhofer, J. (2004) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.2004.00257.x · Cited by 439 · see citing works
Predictors of quality of life among multiple sclerosis patients: a comprehensive analysis
Yamout, B., Issa, Z. A., Herlopian, A., Bejjani, M. E., Khalifa, A., Ghadieh, A. S., & Habib, R. (2013) · European Journal of Neurology · doi:10.1111/ene.12046 · Cited by 135 · see citing works
Quality of life in multiple sclerosis.
Opara, J. A., Jaracz, K., & Brola, W. (2011) · PubMed · Cited by 126 · see citing works
Self-citationFernández, Ó., Baumstarck, K., Siméoni, M.-C., Auquier, P., & on behalf of the MusiQoL study group (2011) · Multiple Sclerosis Journal · doi:10.1177/1352458511407951 · Cited by 108 · see citing works
Jones, K. H., Ford, D. V., Jones, P. A., John, A. M., Middleton, R., Lockhart-Jones, H. M., Peng, J. C., Osborne, L. A., & Noble, J. G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0065640 · Cited by 80 · see citing works
Twork, S., Wiesmeth, S., Spindler, M., Wirtz, M. A., Schipper, S., Pöhlau, D., Klewer, J., & Kügler, J. (2010) · Health and Quality of Life Outcomes · doi:10.1186/1477-7525-8-55 · Cited by 66 · see citing works
General population reference values for 3-level EQ-5D (EQ-5D-3L) questionnaire in Poland
Golicki, D., & Niewada, M. (2015) · Polskie Archiwum Medycyny Wewnętrznej · doi:10.20452/pamw.2638 · Cited by 53 · see citing works
Patti, F., Russo, P., Pappalardo, A., Macchia, F., Civalleri, L., & Paolillo, A. (2006) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2006.10.017 · Cited by 49 · see citing works
Kwiatkowski, A., Marissal, J.-P., Pouyfaucon, M., Vermersch, P., Hautecœur, P., & Dervaux, B. (2014) · BMC Neurology · doi:10.1186/1471-2377-14-115 · Cited by 49 · see citing works
Anagnostouli, M. C., Katsavos, S., Artemiadis, A., Zacharis, M., Argyrou, P., Theotoka, I., Christidi, F., Zalonis, I., & Liappas, I. (2016) · BMC Neurology · doi:10.1186/s12883-016-0621-4 · Cited by 44 · see citing works
Selected aspects of the epidemiology of multiple sclerosis in Poland – a multicentre pilot study
Kułakowska, A., Bartosik-Psujek, H., Hożejowski, R., Mitosek‐Szewczyk, K., Drozdowski, W., & Stelmasiak, Z. (2010) · Neurologia i Neurochirurgia Polska · doi:10.1016/s0028-3843(14)60134-1 · Cited by 37 · see citing works
Brola, W., Sobolewski, P., Fudala, M., Flaga, S., Jantarski, K., Ryglewicz, D., & Potemkowski, A. (2016) · Patient Preference and Adherence · doi:10.2147/ppa.s109520 · Cited by 35 · see citing works
Self-citationBurden and quality of life in caregivers of persons with multiple sclerosis
Opara, J. A., Jaracz, K., & Brola, W. (2012) · Neurologia i Neurochirurgia Polska · doi:10.5114/ninp.2012.31358 · Cited by 34 · see citing works
Self-citationLabuz-Roszak, B. M., Kubicka, K., Pierzchała, K., Horyniecki, M., Machowska-Majchrzak, A., Augustyńska-Mutryn, D., Kosałka, K., Michalski, K., Pyszak, D., & Wach, J. (2013) · PubMed · Cited by 29 · see citing works
Jamróz-Wiśniewska, A., Papuć, E., Bartosik-Psujek, H., et al. (2007) · PubMed · Cited by 29 · see citing works
Demographic, socioeconomic and clinical correlates of self-management in multiple sclerosis
Wilski, M., Tasiemski, T., & Kocur, P. (2014) · Disability and Rehabilitation · doi:10.3109/09638288.2014.993435 · Cited by 27 · see citing works
Wender, M., Pruchnik-Grabowska, D., Hertmanowska, H., Kowal, P., Zielinska, M., Namysł, I., & Marcinkowski, T. (2009) · Acta Neurologica Scandinavica · doi:10.1111/j.1600-0404.1985.tb00866.x · Cited by 26 · see citing works
Variables Related to Working Capability among Swiss Patients with Multiple Sclerosis—A Cohort Study
Findling, O., Baltisberger, M., Jung, S., Kamm, C. P., Mattle, H. P., & Sellner, J. (2015) · PLoS ONE · doi:10.1371/journal.pone.0121856 · Cited by 23 · see citing works
Gupta, S., Goren, A., Phillips, A. L., Dangond, F., & Stewart, M. (2013) · Multiple Sclerosis and Related Disorders · doi:10.1016/j.msard.2013.06.002 · Cited by 23 · see citing works
Quality of life in Polish patients with multiple sclerosis
Mitosek‐Szewczyk, K., Kułakowska, A., Bartosik-Psujek, H., Hożejowski, R., Drozdowski, W., & Stelmasiak, Z. (2014) · Advances in Medical Sciences · doi:10.1016/j.advms.2013.07.002 · Cited by 17 · see citing works
Demographic characteristics of MS patients in Poland's upper Silesia region
Pierzchała, K., Adamczyk-Sowa, M. H., Dobrakowski, P. P., Kubicka, K., Niedziela, N., & Sowa, P. (2014) · International Journal of Neuroscience · doi:10.3109/00207454.2014.937002 · Cited by 14 · see citing works
[Epidemiological aspects of multiple sclerosis in Lublin (Poland)].
Łobińska, A., & Stelmasiak, Z. (2005) · PubMed · Cited by 14 · see citing works
[Epidemiology of multiple sclerosis in the region of Szczecin: prevalence and incidence 1993-1995].
Potemkowski, A. (1999) · PubMed · Cited by 14 · see citing works
Contribution to the epidemiology of multiple sclerosis in Poland
Kowal, P., Wender, M., Pruchnik-Grabowska, D., et al. (1986) · Neurological Sciences · doi:10.1007/bf02230882 · Cited by 7 · see citing works
Karakiewicz, B., Stala, C., Grochans, E., et al. (2010) · PubMed · Cited by 5 · see citing works
Epidemiological Study of Multiple Sclerosis in Western Poland
Cendrowski, W., Wender, M., Dominik, W., et al. (1969) · Springer eBooks · doi:10.1007/978-3-7091-5104-4_18 · Cited by 5 · see citing works
Flagged first, then by citations
Research works printed but not linked: 11
- Compston A, Coles A. Multiple sclerosis. Lancet 2008; 372: 1502-17.
- Potemkowski A. Multiple sclerosis in Poland and worldwide – epidemiological considerations. Aktual Neurol 2009; 9: 91-7.
- Potemkowski A. An epidemiological survey of a focus of multiple sclerosis in the province of Szczecin. Przegl Epidemiol 2001; 55: 331-41.
- Brola W, Fudala M, Flaga S, Ryglewicz D. Need for creating Polish registry of multiple sclerosis patients. Neurol Neurochir Pol 2013; 47: 484-92.
- Brola W, Fudala M, Flaga S, Ryglewicz D, Potemkowski A. Polish registry of multiple sclerosis – current status, perspectives and problems. Aktualn Neurol 2015; 15: 68-73.
- Kurtzke JF. Rating neurological impairment in multiple sclerosis and expanded disability status scale (EDSS). Neurology 1983; 33: 1444-52.
- Rabin R, de Charro F. EQ-5D: a measure of health status from the EuroQol Group. Ann Med 2001; 33: 337-43.
- Golicki D, Niewada M, Jakubczyk M, Wrona W, Hermanowski T. Self-assessed heath status in Poland: EQ-5D findings from the Polish valuation study. Pol Arch Med Wewn 2010; 120: 276-81.
- Opara JA, Jaracz K, Brola W. Quality of life in multiple sclerosis. J Med Life 2010; 3: 352-8.
- Papuć E, Stelmasiak Z. Factors predicting quality of life in a group of Polish respondents with multiple sclerosis: accounting for functional state, socio-demographic and clinical factors. Clin Neurol Neurosurg 2012; 114: 341-6.
- Mitosek-Szewczyk K, Kułakowska A, Bartosik-Psujek H, Hożejowski R, Drozdowski W, Stelmasiak Z. Quality of life in Polish patients with multiple sclerosis. Adv Med Sci 2014; 59: 34-8.
Cited by
Sorted by citations
Quality of life in adults with multiple sclerosis: A systematic review
Gil-González, I., Martín-Rodríguez, A., Conrad, R., & Pérez-San-Gregorio, M. Á. (2020) · BMJ Open · doi:10.1136/bmjopen-2020-041249 · Cited by 263 · see citing works
- Authors
- Brola, W., Sobolewski, P., Fudala, M., Flaga, S., & Jantarski, K.
- Affiliations
- Jan Kochanowski University (PL)
- AGH University of Krakow (PL)
- Corresponding author
- Brola, Waldemar
- Venue
- Medical Studies
- Publisher
- Termedia Sp. z.o.o.
- Published
- 2017-09-30
- Volume
- 33
- Issue
- 3
- Pages
- 191-198
- ISSN
- 1899-1874 (ISSN-L)
- 2300-6722
- OpenAlex
- W2760906362
- Cited by
- 12
- References
- 29
- Citations by year
- 2026: 1 · 2025: 3 · 2024: 2 · 2023: 2 · 2022: 1 · 2021: 1 · 2020: 1 · 2019: 1
- FWCI
- 0.43
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by-nc-sa
- Locations
- Medical Studies (publishedVersion, cc-by-nc-sa)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Topics
- Health Sciences › Medicine › Pathology and Forensic Medicine › Multiple Sclerosis Research Studies
- Social Sciences › Economics, Econometrics and Finance › Economics and Econometrics › Health Systems, Economic Evaluations, Quality of Life
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Keywords
- multiple sclerosis, quality of life, patient-reported outcomes, EQ-5D, EQ-VAS, MSIS-29, disability, disease duration, access to treatment, socioeconomic status, employment, Świętokrzyskie region, socioeconomic burden of disease, health-related quality of life
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