Home blood pressure is the predictor of subclinical target organ damage like ambulatory blood pressure monitoring in untreated hypertensive patients
Open accessAbstract
OBJECTIVE: Home blood pressure (HBP) measurements are known as an important adjunct to office blood pressure (OBP) measurements in clinical practice. But little is known about the relationship between HBP and subclinical target organ damage (TOD) other than left ventricular hypertrophy (LVH). So we investigated the relationship of HBP measurements with subclinical TOD in untreated hypertensive patients. METHODS: We measured ambulatory blood pressure (ABP), HBP and OBP of 93 untreated hypertensive patients (men: 60 and women: 33, mean age, 49±13 years). The ABP was recorded for 24 hours, HBP was measured for one week, and OBP was measured at least in two visits. All BP measurements were taken using automatic BP measuring device. The parameters indicating subclinical TOD were the left-ventricular mass index (LVMI) by transthoracic echocardiography, urinary albumin excretion rate (AER), brachial ankle pulse-wave velocity (PWV), and carotid intima-media thickness (IMT). RESULTS: The LVMI was significantly correlated with systolic HBP and 24 hours systolic ABP, but not with OBP. The AER, PWV and IMT were also significantly correlated with systolic HBP and 24 hours systolic ABP. In a binary logistic regression analysis, systolic HBP, 24 hours systolic and diastolic ABP were the predictors of LVMI, AER and PWV (all p<0.05). CONCLUSION: Our data suggest that HBP is as good as ABP monitoring and superior to OBP measurements in regard to their association with subclinical TOD. Therefore, HBP measurements give valuable information on the subclinical TOD in hypertensive patients in addition to ABP monitoring.
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Statistically significant correlations of home blood pressure with left ventricular mass index have also been reported in other studies not included in the meta-analysis.
“Statistically significant correlations of HBP with LVMI have also been reported in other studies, not included in this meta-analysis [27–31].”
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- Authors
- Her, A.-Y., Kim, Y. H., Rim, S.-J., Kim, J.-Y., Choi, E.-Y., Min, P.-K., Lee, B.-K., Hong, B.-K., & Kwon, H. M.
- Affiliations
- Kangwon National University (KR)
- Yonsei University (KR)
- ORCID
- Venue
- Anadolu Kardiyoloji Dergisi/The Anatolian Journal of Cardiology
- Publisher
- AVES YAYINCILIK A.Ş.
- Published
- 2014-12-25
- Volume
- 14
- Issue
- 8
- Pages
- 711-718
- ISSN
- 1302-8723 (ISSN-L)
- 1308-0032
- OpenAlex
- W1996419055
- Cited by
- 12
- References
- 35
- Citations by year
- 2024: 1 · 2023: 1 · 2021: 1 · 2020: 2 · 2019: 2 · 2018: 1 · 2017: 2 · 2015: 2
- FWCI
- 0.92
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- The Anatolian Journal of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- YUHSpace (Yonsei University Medical Library) (submittedVersion, cc-by-nc-nd)
- Funders
- Kangwon National University
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Blood Pressure and Hypertension Studies
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Disease Prevention
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
- Keywords
- home blood pressure monitoring, subclinical organ damage, untreated hypertension, ambulatory blood pressure monitoring, office blood pressure, left ventricular mass index, urinary albumin excretion rate, pulse wave velocity, carotid intima-media thickness, left ventricular hypertrophy
- MeSH terms
- Brachial Artery, Echocardiography, Female, Heart Ventricles, Humans, Hypertension, Male, Middle Aged, Predictive Value of Tests, Pulsatile Flow, Blood Pressure Monitoring, Ambulatory, Carotid Intima-Media Thickness
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