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Use of Antibiotic-Impregnated Cement in Total Joint Arthroplasty
Abstract
The use of antibiotic-impregnated cement in revision of total hip arthroplasty procedures is widespread, and a substantial body of evidence demonstrates its efficacy in infection prevention and treatment. However, it is not clear that it is necessary or desirable as a routine means of prophylaxis in primary total joint arthroplasty. In the management of infected implant sites, antibiotic-impregnated cement used in one-stage exchange arthroplasties has lowered reinfection rates. In two-stage procedures, use of beads and either articulating or nonarticulating antibiotic-impregnated cement spacers also has lowered reinfection rates. In addition, spacers reduce "dead space," help stabilize the limb, and facilitate reimplantation. Problems associated with antibiotic-impregnated cement in total joint arthroplasty include weakening of the cement and the generation of antibiotic-resistant bacteria in infected implant sites.
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Citations
Cited by
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Cui, Q., Mihalko, W. M., Shields, J. S., Ries, M., & Saleh, K. J. (2007) · The Journal of Bone and Joint Surgery-American Volume · doi:10.2106/00004623-200704000-00026 · Cited by 377
Springer, B. D., Lee, G.-C., Osmon, D., Haidukewych, G. J., Hanssen, A. D., & Jacofsky, D. J. (2004) · Clinical Orthopaedics and Related Research · doi:10.1097/01.blo.0000144476.43661.10 · Cited by 273
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Metadata
- Authors
- Joseph, T. N., Chen, A. L., & Di Cesare, P. E.
- Venue
- Journal of the American Academy of Orthopaedic Surgeons
- Published
- 2003-01
- Volume
- 11
- Issue
- 1
- Pages
- 38-47
- ISSN
- 1067-151X (ISSN-L)
- OpenAlex
- W2164207700
- Cited by
- 224
- References
- 0
- FWCI
- 6.58
- Type
- journal article
- Language
- en
- Open access
- closed
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- Joseph, T. N., Chen, A. L., & Di Cesare, P. E. (2003). Use of Antibiotic-Impregnated Cement in Total Joint Arthroplasty. Journal of the American Academy of Orthopaedic Surgeons. https://doi.org/10.5435/00124635-200301000-00006
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
