Cited by 22Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and MetabolismExercise and Physiological Responses

Effects of short-term exercise on adiponectin and adiponectin receptor levels in rats

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Zeng, Qin, Fu, Ling, Takekoshi, Kazuhiro, Kawakami, Yasushi, Isobe, Kazumasa·2007·Journal of Atherosclerosis and Thrombosis

Abstract

AIM: Adiponectin reportedly reduces insulin resistance. Exercise has also been shown to lessen insulin resistance, although it is not well known whether exercise increases levels of adiponectin and/or its receptors nor whether it effects are dependent on exercise intensity and/or period. We previously reported that blood adiponectin levels increased by 150% in animals that exercised at a rate of 30 m/min for 60 minutes, 2 days per week, and adiponectin receptor 1 (AdipoR1) mRNA levels in muscle increased up to 4 times in response to exercise at a rate of 25 m/min for 30 min, 5 days per week for 12 weeks. METHODS: In light of this information, we examined the effects of short-term exercise on adiponectin, and adiponectin receptor levels in rats, using ELISA and real-time PCR. RESULTS: Our data showed that adiponectin mRNA levels in adipose tissue increased by 280% in rats exercised at a rate of 30 m/min for 60 minutes for 2 weeks and correlated with the exercise time periods. No effects of short-term exercise on adiponectin receptor 1 mRNA in muscle were observed. CONCLUSION: Thus, long-term exercise may be required to regulate adiponectin receptor 1 mRNA expression in muscle and adiponectin mRNA expression in adipose tissue.

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  1. Kadowaki T and Yamauchi T: Adiponectin and adiponec- tin receptors. Endocr Rev, 2005; 26:439-451
  2. Lawler JM, Powers SK, Hammeren J, and Martin AD: Ox- ygen cost of treadmill running in 24-mo-old Fisher-344 rats. Med Sci Sports Exerc, 1993; 25:1259-1264

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Authors
Zeng, Q., Fu, L., Takekoshi, K., Kawakami, Y., & Isobe, K.
Affiliations
University of Tsukuba (JP)
Venue
Journal of Atherosclerosis and Thrombosis
Published
2007
Volume
14
Issue
5
Pages
261-265
ISSN
  • 1340-3478 (ISSN-L)
  • 1880-3873
OpenAlex
W2010062262
Cited by
22
References
22
Citations by year
2024: 1 · 2020: 1 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 2 · 2013: 3
FWCI
1.83
Type
journal article
Language
en
Open access
Licence
cc-by-nc-sa
Locations
  • Journal of Atherosclerosis and Thrombosis (publishedVersion, cc-by-nc-sa)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
  • Health Sciences › Medicine › Physiology › Adipose Tissue and Metabolism
  • Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
Keywords
adiponectin, AdipoR1, short-term exercise, exercise intensity, exercise duration, adipose tissue, skeletal muscle, insulin resistance, gene expression, rats
MeSH terms
Adipose Tissue, Animals, Blood Glucose, Enzyme-Linked Immunosorbent Assay, Epinephrine, Lipids, Physical Conditioning, Animal, RNA, Messenger, Time, Gene Expression, Reverse Transcriptase Polymerase Chain Reaction, Rats, Adiponectin, Receptors, Adiponectin

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