Effects of short-term exercise on adiponectin and adiponectin receptor levels in rats
Open accessAbstract
AIM: Adiponectin reportedly reduces insulin resistance. Exercise has also been shown to lessen insulin resistance, although it is not well known whether exercise increases levels of adiponectin and/or its receptors nor whether it effects are dependent on exercise intensity and/or period. We previously reported that blood adiponectin levels increased by 150% in animals that exercised at a rate of 30 m/min for 60 minutes, 2 days per week, and adiponectin receptor 1 (AdipoR1) mRNA levels in muscle increased up to 4 times in response to exercise at a rate of 25 m/min for 30 min, 5 days per week for 12 weeks. METHODS: In light of this information, we examined the effects of short-term exercise on adiponectin, and adiponectin receptor levels in rats, using ELISA and real-time PCR. RESULTS: Our data showed that adiponectin mRNA levels in adipose tissue increased by 280% in rats exercised at a rate of 30 m/min for 60 minutes for 2 weeks and correlated with the exercise time periods. No effects of short-term exercise on adiponectin receptor 1 mRNA in muscle were observed. CONCLUSION: Thus, long-term exercise may be required to regulate adiponectin receptor 1 mRNA expression in muscle and adiponectin mRNA expression in adipose tissue.
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Effects of acute exercise on ApN parameters are inconsistent, if any.
“Effects of acute exercise on ApN parameters are inconsistent, if any [77,78].”
From Adiponectin and Its Mimics on Skeletal Muscle: Insulin Sensitizers, Fat Burners, Exercise Mimickers, Muscling Pills … or Everything Together? (2020) · cites this paper as [78]
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- Authors
- Zeng, Q., Fu, L., Takekoshi, K., Kawakami, Y., & Isobe, K.
- Affiliations
- University of Tsukuba (JP)
- Venue
- Journal of Atherosclerosis and Thrombosis
- Publisher
- Japan Atherosclerosis Society
- Published
- 2007
- Volume
- 14
- Issue
- 5
- Pages
- 261-265
- ISSN
- 1340-3478 (ISSN-L)
- 1880-3873
- OpenAlex
- W2010062262
- Cited by
- 22
- References
- 22
- Citations by year
- 2024: 1 · 2020: 1 · 2019: 1 · 2018: 1 · 2017: 1 · 2016: 2 · 2013: 3
- FWCI
- 1.83
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by-nc-sa
- Locations
- Journal of Atherosclerosis and Thrombosis (publishedVersion, cc-by-nc-sa)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Adipokines, Inflammation, and Metabolic Diseases
- Health Sciences › Medicine › Physiology › Adipose Tissue and Metabolism
- Health Sciences › Medicine › Rehabilitation › Exercise and Physiological Responses
- Keywords
- adiponectin, AdipoR1, short-term exercise, exercise intensity, exercise duration, adipose tissue, skeletal muscle, insulin resistance, gene expression, rats
- MeSH terms
- Adipose Tissue, Animals, Blood Glucose, Enzyme-Linked Immunosorbent Assay, Epinephrine, Lipids, Physical Conditioning, Animal, RNA, Messenger, Time, Gene Expression, Reverse Transcriptase Polymerase Chain Reaction, Rats, Adiponectin, Receptors, Adiponectin
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