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Cited by 133Obstructive Sleep Apnea ResearchSleep and related disordersNon-Invasive Vital Sign Monitoring

Validation of Watch-PAT-200 Against Polysomnography During Pregnancy

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O’Brien, Louise M., Bullough, Alexandra S., Shelgikar, Anita V., Chames, Mark C., Armitage, Roseanne, Chervin, Ronald D.·2012·Journal of Clinical Sleep Medicine
DOI 10.5664/jcsm.1916PMC PMC3365087
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Abstract

Study objectives To determine the relationships between key variables obtained from ambulatory polysomnography (PSG) and the wrist-worn Watch-PAT 200 device in pregnant women. Methods In this prospective cohort study, women in their third trimester of pregnancy underwent full overnight home PSG using the 22-channel MediPalm system and the Watch-PAT 200 device. PSGs were scored by a blinded, experienced technologist using AASM 2007 criteria; the Watch-PAT was scored automatically by the manufacturer's proprietary software. Results A total of 31 pregnant women were studied. Mean age was 30.2 ± 7.1 years; mean gestational age was 33.4 ± 3.0 weeks; mean BMI was 31.9 ± 8.1 kg/m(2); 39% of women were nulliparous. Key variables generated by PSG and Watch-PAT correlated well over a wide range, including the apnea-hypopnea index (AHI, r = 0.76, p < 0.001); respiratory disturbance index (RDI, r = 0.68, p < 0.001), mean oxygen saturation (r = 0.94, p < 0.001), and minimum oxygen saturation (r = 0.88, p < 0.001). The area under the curve for AHI ≥ 5 and RDI ≥ 10 were 0.96 and 0.94, respectively. Association between stage 3 sleep on PSG and deep sleep on Watch-PAT was poor. Watch-PAT tended to overscore RDI, particularly as severity increased. Conclusions Among pregnant women, Watch-PAT demonstrates excellent sensitivity and specificity for identification of obstructive sleep apnea, defined as AHI ≥ 5 on full PSG. Watch-PAT may overestimate RDI somewhat, especially at high RDI values.

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  • A single study evaluated the performance of PAT, oximetry, and actigraphy against simultaneous unattended in-home PSG and reported a sensitivity of 0.88 (95% CI: 0.47 to 1.00), specificity of 0.87 (95% CI: 0.66 to 0.97) and accuracy of 88% (95% CI: 50 to 100%) in high-risk patients using a cutoff of AHI ≥ 5.

    “A single study evaluated the performance of PAT, oximetry, and actigraphy against simultaneous unattended in-home PSG and reported a sensitivity of 0.88 (95% CI: 0.47 to 1.00), specificity of 0.87 (95% CI: 0.66 to 0.97) and accuracy of 88% (95% CI: 50 to 100%) in high-risk patients using a cutoff of AHI ≥ 5.”

    From Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: An American Academy of Sleep Medicine Clinical Practice Guideline (2017) · cites this paper as [104]

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  • These findings would result in 121 misdiagnosed patients out of 1,000 tested in a high-risk population (based on a prevalence of 87%), and 125 misdiagnosed patients out of 1,000 tested in a low-risk population (based on a prevalence of 55%).

    “These findings would result in 121 misdiagnosed patients out of 1,000 tested in a high-risk population (based on a prevalence of 87%), and 125 misdiagnosed patients out of 1,000 tested in a low-risk population (based on a prevalence of 55%)”

    From Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: An American Academy of Sleep Medicine Clinical Practice Guideline (2017) · cites this paper as [104]

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Cited by

Sorted by citations

Authors
O’Brien, L. M., Bullough, A. S., Shelgikar, A. V., Chames, M. C., Armitage, R., & Chervin, R. D.
Affiliations
University of Michigan (US)
ORCID
Venue
Journal of Clinical Sleep Medicine
Publisher
Springer Science and Business Media LLC
Published
2012-06-15
Volume
8
Issue
3
Pages
287-294
ISSN
  • 1550-9389 (ISSN-L)
  • 1550-9397
DOI
10.5664/jcsm.1916
PMC
PMC3365087
OpenAlex
W1988368504
Cited by
133
References
0
Citations by year
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FWCI
4.02
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Clinical Sleep Medicine (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
National Heart, Lung, and Blood Institute (R21HL089918, R21HL087819, K23HL095739)
Topics
  • Health Sciences › Medicine › Physiology › Obstructive Sleep Apnea Research
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
  • Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
Keywords
ambulatory polysomnography, pregnancy, obstructive sleep apnea, apnea-hypopnea index, respiratory disturbance index, oxygen saturation, third trimester, device validation
MeSH terms
Adult, Female, Humans, Pregnancy, Pregnancy Complications, Prospective Studies, Sensitivity and Specificity, Sleep, Single-Blind Method, Polysomnography, Sleep Apnea, Obstructive

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