Antioxidant Enzyme
Abstract
Free radicals are constantly formed in living cells and removed by antioxidant defenses. Antioxidant enzymes are the main line of defense against free radicals in animal and plant cells. Uncontrolled generation ROS are involved in a number of human disease states, including diabetes and cancer due to disturbance in cellular and molecular processes including cell growth, differentiation and proliferation. When cells are exposed to oxidative stress a defense system endorses the expression and regulation of number of antioxidant enzymes as a defense mechanism to protect them from the damage induced by free radicals. Based on this fact, the book "Antioxidant Enzymes" was designed to overview the importance of the antioxidant enzymes in human and plant cells against toxic free radicals, their relationship with several pathophysiologic processes and their possible therapeutic application.
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Vitamins A, C, and E from diet can act as antioxidants and are found in high concentrations in the epidermis and dermis.
“Other molecules derived from our diet, such as vitamins A, C, and E, can also act as antioxidants which are found in high concentrations in the epidermis and dermis [2,[15][16][17].”
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- Authors
- El-Missiry, M. A.
- Corresponding author
- Mohammed Amr El-Missiry
- Venue
- InTech eBooks
- Publisher
- InTech
- Published
- 2012-10-03
- DOI
- 10.5772/2895
- OpenAlex
- W388503848
- Cited by
- 41
- References
- 0
- Citations by year
- 2025: 3 · 2024: 6 · 2023: 5 · 2022: 4 · 2021: 5 · 2020: 9 · 2019: 1 · 2018: 2 · 2017: 2 · 2016: 1 · 2015: 2 · 2014: 1
- FWCI
- 0.80
- Type
- book
- Language
- en
- Open access
- closed
- Locations
- InTech eBooks (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Redox biology and oxidative stress
- Health Sciences › Medicine › Biochemistry › Antioxidant Activity and Oxidative Stress
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Glutathione Transferases and Polymorphisms
- Keywords
- antioxidant enzymes, free radicals, reactive oxygen species, oxidative stress, antioxidant defense, plant cells, human disease, diabetes mellitus, cancer, therapeutic applications
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