Comparison of the Effect of Mindfulness-based Cognitive Therapy Accompanied by Pharmacotherapy With Pharmacotherapy Alone in Treating Dysthymic Patients
Open accessAbstract
BACKGROUND: Dysthimia in adults is a chronic depression disorder which is characterized by a mild depression for at least 2 years. Remarkable psycho-social involvements, greater disturbances in psycho-social functions compared to other forms of depression and lack of definite findings about preferred treatment for this disorder led us to evaluate the effectiveness of Mindfulness based cognitive therapy (MBCT) method adjunct to pharmacotherapy compared with pharmachothrapy alone in treating dysthymia in this thesis. OBJECTIVES: This study aimed to evaluate the effectiveness of mindfulness-based cognitive therapy on a chronic type of depression disorder called dysthymia. PATIENTS AND METHODS: This study is a clinical trial of an interventional method which was carried out on dysthymic and double depressed patients who had referred to psychiatric clinics of Shiraz University of Medical Sciences, Shiraz, Iran. In doing so, 50 patients above the age of 18 were selected through convenience sampling and assigned into intervention and control groups. The control group only received medications while the intervention group in addition to receiving medication, participated in 8 sessions of a mindfulness based cognitive therapy course which was held once a week and each session lasted for 2 to 2.5 hours. All the participants filled out Beck Depression Inventory II and five facet mindfulness questionnaire. The data were analyzed using the SPSS statistical software (version 16) and univariate covariance and independent t test statistical methods. RESULTS: In this study, no statistically significant differences were found between the two groups regarding the demographic characteristics. The mean difference between the two groups was statistically significant for the variables in post-test considering the pre-test. The experimental group participants showed significant improvement in terms of the defined variables; a trend which was not observed in the control group participants. CONCLUSION: The results of this study show that adding MBCT to pharmacotherapy in treatment of dysthymic patients can cause significant improvement in depression symptoms and mindfulness skills in patients compared to pharmacotherapy alone.
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When combined with psychopharmacology, MBCT caused significant symptom improvement in individuals with a history of suicidal depression.
“when combined with psychopharmacology, it caused significant symptom improvement (Omidi et al., 2013)”
From Mapping mindfulness in psychotherapy: a scoping review on conceptualization, applications, and research directions (2026) · cites this paper as Omidi et al., 2013
The Abstract conclusion and Discussion report significant improvement in depression symptoms when MBCT was added to pharmacotherapy for dysthymic patients. The Study Subjects section describes participants with dysthymia, not a group selected for a history of suicidal depression; that population qualifier is unsupported. (LLM, conf=0.89)
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- Authors
- Omidi, A., Hamidian, S., Mousavinasab, S. M., & Naziri, G.
- Affiliations
- Kashan University of Medical Sciences (IR)
- Shiraz University of Medical Sciences (IR)
- Islamic Azad University of Shiraz (IR)
- Corresponding author
- Omidi, Abdollah
- Venue
- Iranian Red Crescent Medical Journal
- Publisher
- DoNotEdit
- Published
- 2013-03-05
- Volume
- 15
- Issue
- 3
- Pages
- 239-44
- ISSN
- 2074-1804 (ISSN-L)
- 2074-1812
- PMC
- PMC3745754
- OpenAlex
- W2092143662
- Cited by
- 22
- References
- 30
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 2 · 2022: 2 · 2021: 2 · 2020: 1 · 2019: 2 · 2018: 2 · 2017: 1 · 2016: 1 · 2015: 2 · 2014: 3
- FWCI
- 2.23
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Licence
- cc-by
- Locations
- Iranian Red Crescent Medical Journal (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Social Sciences › Psychology › Clinical Psychology › Psychotherapy Techniques and Applications
- Keywords
- mindfulness-based cognitive therapy, dysthymia, chronic depression, pharmacotherapy, adjunctive psychotherapy, double depression, depressive symptoms, mindfulness skills, Beck Depression Inventory-II
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