Inhibition of dehydrogenase activity in pathogenic bacteria isolates by aqueous extracts of Musa paradisiaca (var Sapientum)
Open accessAbstract
Inhibition of dehydrogenase activity in pathogenic bacteria isolates by aqueous extract from the unripe fruit peels (called the bark) and leaves of Musa paradisiaca var sapientum were investigated via dehydrogenase assay using 2,3,5-triphenyl tetrazolium chloride (TTC) as the electron acceptor. Pure cultures of Staphylococcus and Pseudomonas species were exposed to varied concentrations of the extract [0 – 2000 µg/ml]. The extracts exhibited concentration dependent response against the tested organisms. Dehydrogenase activities (mg Formazan/mg cell dry weight/h) in the Gram-positive Staphylococcus sp. and Gram-negative Pseudomonas sp. were 1.125 ± 0.056 and 0.740 ± 0.040, respectively, and were progressively inhibited in the pure cultures. Threshold inhibitory concentrations (IC50) of M. paradisiaca bark extract were 143.5 and 183.1 µg/ml against Staphylococcus and Pseudomonasspecies, respectively, while the threshold inhibitory concentrations (IC50) of M. paradisiaca leaf extract were 401.2 and 594.6 µg/ml, respectively. The IC100 of the leaf extract against Staphylococcus and Pseudomonas species were 1850 and 2000 µg/ml respectively, while the bark could not completely inhibit the organisms at the tested concentrations. The bark and leaves of M. paradisiacamay be an available source of raw material for the production of chemotherapeutic agents against pathogenic bacteria. Key words: Musa paradisiaca, dehydrogenase activity, pathogenic bacteria..
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Phenolic compounds exhibit antioxidant activity by neutralizing lipid free radicals or preventing hydrogen peroxides from disintegrating into free radicals.
“Phenolic compounds are the most essential plant elements that exhibit antioxidant activity by neutralizing lipid free radicals or by preventing hydrogen peroxides from disintegration into free radicals [93,94].”
From Functional, nutritional and medicinal potential of banana peel (2023) · cites this paper as [93]
The Results and Discussion section reports phytochemicals in Musa paradisiaca extracts and suggests possible antimicrobial activity, but does not discuss antioxidant activity. Searches for phenolic antioxidants, lipid free radicals, and hydrogen peroxide found no passage addressing the claimed mechanisms; page numbers were unavailable in our copy. (LLM, conf=0.77)
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Medicinal plants and traditional medicine in Africa
Sofowora, A. (1982) · Medical Entomology and Zoology · Cited by 3,460 · see citing works
Higher plants--the sleeping giant of drug development.
Farnsworth, N. R., & Morris, R. W. (1976) · PubMed · Cited by 207 · see citing works
Kelly, J. J., & Tate, R. L. (1998) · Journal of Environmental Quality · doi:10.2134/jeq1998.00472425002700030019x · Cited by 141 · see citing works
Microbial biomass dynamics following addition of metal-enriched sewage sludges to a sandy loam
Chander, K., Brookes, P. C., & Harding, S. A. (1995) · Soil Biology and Biochemistry · doi:10.1016/0038-0717(95)00074-o · Cited by 138 · see citing works
Rogers, J. E., & Li, S. W. (1985) · Bulletin of Environmental Contamination and Toxicology · doi:10.1007/bf01609817 · Cited by 95 · see citing works
Available, N. A. N., & Tarafdar, J. C. (2003) · Biology and Fertility of Soils · doi:10.1007/s00374-003-0600-y · Cited by 84 · see citing works
Kim, C. (1994) · Water Research · doi:10.1016/0043-1354(94)90198-8 · Cited by 59 · see citing works
Phytochemical and antimicrobial activity of ethanolic extract of Landolphia owariensis leaf
Nwaogu, L., Alisi, C., Ibegbulem, C., & Igwe, C. U. (2007) · AFRICAN JOURNAL OF BIOTECHNOLOGY · doi:10.5897/ajb2007.000-2105 · Cited by 57 · see citing works
Self-citationAoyama, M., & Nagumo, T. (1997) · Soil Science & Plant Nutrition · doi:10.1080/00380768.1997.10414786 · Cited by 52 · see citing works
Mathew, M., & Obbard, J. P. (2001) · Biotechnology Letters · doi:10.1023/a:1005613406948 · Cited by 48 · see citing works
5 - Identification, Collection and Domestication of Medicinal Plants in Southeastern Nigeria
Nwufo, M. I., & Ibe, Α. Ε. (2005) · Africa Development · doi:10.4314/ad.v30i3.22230 · Cited by 30 · see citing works
Response of planktonic bacteria of New Calabar River to zinc stress
Nweke, C. O., Okolo, J. C., Nwanyanwu, C. E., & Alisi, C. (2006) · International Journal of Plant and Animal Sciences · doi:10.5897/ajb06.128 · Cited by 24 · see citing works
Self-citationNwaogu, L., & Ujowundu, C. O. (2008) · AFRICAN JOURNAL OF BIOTECHNOLOGY · doi:10.5897/ajb07.853 · Cited by 17 · see citing works
Flagged first, then by citations
Research works printed but not linked: 2
- Nweke CO, Alisi CS, Okolo JC, Nwanyanwu CE (2007). Toxicity of Zinc to heterotrophic bacteria of tropical river sediments. Appl. Eco. Envron. Res. 5(1): 123-132.
- Trease GE, Evans WC (1989). Pharmacognosy. 13th edition. Bacilliere Tinall Ltd, London. pp. 5-9.
Cited by
Sorted by citations
(2011) · Journal of Applied Pharmaceutical Science · Cited by 146 · see citing works
Medicinal plants used by the Tamang community in the Makawanpur district of central Nepal
Luitel, D. R., Rokaya, M. B., Timsina, B., & Münzbergová, Z. (2014) · Journal of Ethnobiology and Ethnomedicine · doi:10.1186/1746-4269-10-5 · Cited by 145 · see citing works
Therapeutic potentials and compositional changes of valuable compounds from banana- A review
Qamar, S., & Shaikh, A. (2018) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2018.06.016 · Cited by 123 · see citing works
Microbial activities and phosphorus cycling: An application of oxygen isotope ratios in phosphate
Stout, L. M., Joshi, S. R., Kana, T. M., & Jaisi, D. P. (2014) · Geochimica et Cosmochimica Acta · doi:10.1016/j.gca.2014.04.020 · Cited by 75 · see citing works
Galactagogue effects of Musa x paradisiaca flower extract on lactating rats
Mahmood, A., Omar, M. N., & Ngah, N. (2012) · Asian Pacific Journal of Tropical Medicine · doi:10.1016/s1995-7645(12)60164-3 · Cited by 47 · see citing works
Jouneghani, R. S., Castro, A. H. F., Panda, S. K., Swennen, R. L., & Luyten, W. H. M. L. (2020) · Foods · doi:10.3390/foods9040435 · Cited by 42 · see citing works
Phytochemicals constituent and antioxidant activities in Musa x paradisiaca flower
Mahmood, A., Ngah, N., & Omar, M. N. (2011) · Cited by 41 · see citing works
Antibacterial and toxicity studies of the ethanol extract of Musa paradisiaca leaf
Asuquo, E. G., & Udobi, C. E. (2016) · Cogent Biology · doi:10.1080/23312025.2016.1219248 · Cited by 40 · see citing works
Kuppusamy, A., & Ulagesan, S. (2014) · International Wound Journal · doi:10.1111/iwj.12371 · Cited by 39 · see citing works
Oresanya, I. O., Sonibare, M. A., Guèye, B., Balogun, F. O., Adebayo, S. A., Ashafa, A. O. T., & Morlock, G. E. (2020) · Journal of Food Biochemistry · doi:10.1111/jfbc.13137 · Cited by 35 · see citing works
Rao, U. M. (2016) · Malaysian Journal of Analytical Science · doi:10.17576/mjas-2016-2005-26 · Cited by 32 · see citing works
ANTIULCER ACTIVITY OF Musa paradisiaca (BANANA) TEPAL AND SKIN EXTRACTS IN ULCER INDUCED ALBINO MICE
Ahmad, B. A. (2016) · Malaysian Journal of Analytical Science · doi:10.17576/mjas-2016-2005-27 · Cited by 31 · see citing works
Wound healing and antioxidant capacity of Musa paradisiaca Linn. peel extracts
Padilla‐Camberos, E., Flores-Fernández, J. M., Canales-Aguirre, A. A., Barragán-Álvarez, C. P., Gutiérrez-Mercado, Y. K., & Lugo‐Cervantes, E. (2016) · Journal of Pharmacy & Pharmacognosy Research · doi:10.56499/jppres16.124_4.5.165 · Cited by 29 · see citing works
Burdock, T. J., Brooks, M. S., & Ghaly, A. E. (2011) · Journal of Bioprocessing & Biotechniques · doi:10.4172/2155-9821.1000101 · Cited by 26 · see citing works
Wu, H., Xu, F., Hao, J., Yang, Y., & Wang, X. (2015) · International Conference on Material, Mechanical and Manufacturing Engineering (IC3ME) · doi:10.2991/ic3me-15.2015.44 · Cited by 25 · see citing works
Sivasamugham, L. A., Nimalan, V., & Subramaniam, G. (2020) · South African Journal of Chemical Engineering · doi:10.1016/j.sajce.2020.09.007 · Cited by 23 · see citing works
Sonibare, M. A., Ayoola, I. O., Guèye, B., Abberton, M. T., Dsouza, R. N., & Kuhnert, N. (2018) · Journal of Food Measurement & Characterization · doi:10.1007/s11694-018-9725-4 · Cited by 21 · see citing works
Oresanya, I. O., Sonibare, M. A., Guèye, B., Paliwal, R., Abberton, M. T., & Morlock, G. E. (2019) · Journal of Chromatography A · doi:10.1016/j.chroma.2019.460774 · Cited by 20 · see citing works
Iheme, C. I., Elemike, E. E., Igwe, C. U., Ujowundu, F. N., Ogbonna, C. U., Uche, Z. C., Okoro, C. O., Hossain, I., & Onwudiwe, D. C. (2023) · Inorganic Chemistry Communications · doi:10.1016/j.inoche.2023.111864 · Cited by 18 · see citing works
Nwanyanwu, C. E., & Abu, G. O. (2010) · Ambiente e Agua - An Interdisciplinary Journal of Applied Science · doi:10.4136/ambi-agua.133 · Cited by 17 · see citing works
Self-citationFlavonoids from Nigerian indigenous medicinal plants and their bioactivities: A review
Achika, J. I., Yusuf, A. J., Ayo, R. G.-O., & Liman, D. U. (2023) · Phytomedicine Plus · doi:10.1016/j.phyplu.2023.100405 · Cited by 15 · see citing works
Perceptions of the use of indigenous leaves as packaging materials in the ready-to-eat cornmeals
Mensah, J., Adei, E., Adei, D., & Ashie, M. (2012) · International Journal of Biological and Chemical Sciences · doi:10.4314/ijbcs.v6i3.12 · Cited by 14 · see citing works
Bioactivity studies on Musa seminifera Lour
Sarker, S. D., Mondal, H., Gofur, R., Billah, M. M., Nahar, L., Saha, S., & Shilpi, J. A. (2013) · Pharmacognosy Magazine · doi:10.4103/0973-1296.117827 · Cited by 14 · see citing works
Functional, nutritional and medicinal potential of banana peel
Hashim, M. (2023) · Pure and Applied Biology · doi:10.19045/bspab.2023.120049 · Cited by 11 · see citing works
Gunavathy, N. (2013) · IOSR Journal of Applied Chemistry · doi:10.9790/5736-0522935 · Cited by 10 · see citing works
Alisi, C. S. (2014) · International Journal of TROPICAL DISEASE & Health · doi:10.9734/ijtdh/2012/1050 · Cited by 10 · see citing works
Self-citationAntimicrobial activity of bBanana (Musa paradisiaca L.) peels against food borne pathogenic microbes
Ahmed, Q. U., Helaluddin, A. B. M., & Jalal, K. C. A. (2014) · The International Islamic University Malaysia Repository (The International Islamic University Malaysia) · Cited by 8 · see citing works
Kasotia, A., & Choudhary, D. K. (2014) · Proceedings of the National Academy of Sciences India Section B Biological Sciences · doi:10.1007/s40011-014-0416-6 · Cited by 8 · see citing works
Gunavathy, N., & Padmavathy, S. (2014) · Cited by 7 · see citing works
Maregesi, S. M., Kagashe, G. A. B., & Felix, F. F. (2014) · Journal of Cosmetics Dermatological Sciences and Applications · doi:10.4236/jcdsa.2014.45047 · Cited by 6 · see citing works
Antidermatophytic Activities of Musa sapientum Methanol Leaf Extract in-vitro
Ige, A. O., & Mebude, O. (2015) · British Microbiology Research Journal · doi:10.9734/bmrj/2015/19261 · Cited by 6 · see citing works
Žorža, L., Dēliņa, A., Selga, T., & Muter, O. (2023) · Fermentation · doi:10.3390/fermentation9080699 · Cited by 4 · see citing works
ANTHELMINTIC ACTIVITY OF MUSA PARADISIACA (L.) CV. PUTTABALE
Venkatesh, V., Krishna, V., Kumar, K., Pradeepa, K., Kumar, S. R. S., & Vijay, K. (2013) · International Journal of Pharmaceutical Sciences and Drug Research · doi:10.25004/ijpsdr.2013.050206 · Cited by 4 · see citing works
A Comprehensive Review on Nutrient Profile and Pharmacological Benefits of Musa paradisiaca
Jaleel, A., Jacob, S., Ghosh, S., & Suresh, A. (2024) · Sciences of Phytochemistry · doi:10.58920/sciphy0302254 · Cited by 8 · see citing works
Khan, A., Swennen, R. L., Panda, S. K., Schoofs, L., & Luyten, W. H. M. L. (2025) · Electronic Journal of Biotechnology · doi:10.1016/j.ejbt.2025.07.005 · Cited by 3 · see citing works
Efect of Phytol on Dehydrogenase Activity of Bacterial Isolates from Grilled Meat
Eluchie, C. N., Oranusi, S. U., Akujobi, C. O., & Alagbaoso, S. O. (2016) · American journal of food science and technology · doi:10.12691/ajfst-4-1-1 · Cited by 3 · see citing works
Self-citationSalau, B. A. (2013) · IOSR Journal of Pharmacy and Biological Sciences · doi:10.9790/3008-0810712 · Cited by 3 · see citing works
Iheme, C. I., Asika, K. E., Ugwor, E. I., Ogbonna, C. U., Uzoka, U. H., Nwabueze, O. S., Ezirim, A. U., Nkwoada, A. U., Oguzie, C. K., Okoli, U. A., et al. (2025) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2025.108764 · Cited by 3 · see citing works
Self-citationUjowundu, F. N. (2017) · International Journal of Pharmacology Phytochemistry and Ethnomedicine · doi:10.18052/www.scipress.com/ijppe.8.27 · Cited by 2 · see citing works
Jyothirmayi, N. (2012) · Cited by 1 · see citing works
Odion, E. E., Ogboru, R. O., Obarisiagbon, P. A., & Oboigba, O. J. (2021) · Cited by 1 · see citing works
Al-Fahdawi, S. T. A., & Al-Warshan, S. H. S. (2023) · IOP Conference Series Earth and Environmental Science · doi:10.1088/1755-1315/1158/7/072004 · Cited by 1 · see citing works
Osei-Asibey, R. K. (2023) · International Journal of Technology and Management Research · doi:10.47127/ijtmr.v8i1.155 · Cited by 1 · see citing works
Nisar, M. S., Khan, A. K., Fatima, G. A., Ahmed, I., Ullah, K. S., & Hameed, S. A. (2023) · Sarhad Journal of Agriculture · doi:10.17582/journal.sja/2023/39.4.840.847 · Cited by 1 · see citing works
Njoku, H., Akujobi, C., & Ogbulie, J. (2011) · International Journal of Biological and Chemical Sciences · doi:10.4314/ijbcs.v4i4.63046
Self-citationAsuquo, E. G., Udobi, C. E., & Udobi, E. (2016)
Ujowundu, C. O., Igwe, C. U., Alisi, C. S., Nwaogu, L., Ogbuagu, D. H., & Onwuliri, V. A. (2017) · African Journal of Pharmacy and Pharmacology · doi:10.5897/ajpp2017.4810
Self-citation(2023) · Journal of Sustainable Veterinary and Allied Sciences · doi:10.54328/covm.josvas.2023.138
Giri, P., Garg, P., Srivastava, P., & Trivedi, M. (2025) · Toxicology International · doi:10.18311/ti/2025/v32i3/48156
- Authors
- Alisi, C. S., Nwanyanwu, C. E., Akujobi, C. O., & Ibegbulem, C. O.
- ORCID
- Akujobi, C O
- Venue
- African Journal of Biotechnology
- Publisher
- Academic Journals
- Published
- 2008-06-17
- Volume
- 7
- Issue
- 12
- Pages
- 1821-1825
- ISSN
- 1684-5315 (ISSN-L)
- OpenAlex
- W2166721197
- Cited by
- 50
- References
- 13
- Citations by year
- 2025: 3 · 2024: 1 · 2023: 7 · 2022: 1 · 2021: 2 · 2020: 3 · 2019: 1 · 2018: 2 · 2017: 2 · 2016: 6 · 2015: 2 · 2014: 8 · 2013: 4 · 2012: 3
- FWCI
- 2.67
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by
- Locations
- AFRICAN JOURNAL OF BIOTECHNOLOGY (publishedVersion, cc-by)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Banana Cultivation and Research
- Keywords
- Musa paradisiaca, dehydrogenase inhibition, pathogenic bacteria, Staphylococcus, Pseudomonas, aqueous plant extract, banana leaf extract, antibacterial activity, anticancer agents
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
