Supercritical fluid extraction of beta-ecdysone from Brazilian ginseng (Pfaffia glomerata) roots
Open accessAbstract
Ecdysteroids have been found in a variety of plants and have several valuable biological properties. Beta-ecdysone is the major biologically active ecdysteroid that can be isolated from Pfaffia glomerata roots. Pfaffia glomerata is a medicinal plant known in Brazil as “Brazilian ginseng,” and this plant has been used as a substitute for “Asian” ginseng due their similar morphologies and bioactive properties. In this work, supercritical fluid extraction (SFE) using carbon dioxide (CO2) was used to obtain beta-ecdysone-rich extracts from Brazilian ginseng roots. The effects of pressure (20 and 30 MPa) and cosolvent amount (10, 15, 75 and 90% of Ethanol, EtOH) on the behavior of the overall extraction curve (OEC) and beta-ecdysone content were studied. Larger amounts of beta-ecdysone were obtained in shorter processing times using CO2: EtOH (85:15, v/v) as the extracting solvent at 20 MPa. Higher amounts of EtOH in the solvent mixture leads to increased extraction yield as well as increased beta-ecdysone content.
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Supercritical fluid extraction with critical carbon dioxide modified with methanol, ethanol or DMSO is an effective, high-yield method for extracting ecdysteroids from plant materials.
“Supercritical fluid with critical carbon dioxide modified with methanol, ethanol or DMSO is an effective, high-yield extraction method for ecdysteroid-containing plant materials [110-113].”
From Ecdysteroids (2021) · cites this paper as [113]
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- Authors
- C. N. Debien, I., & Angela A. Meireles, M.
- Venue
- Food and public health
- Publisher
- Scientific and Academic Publishing
- Published
- 2014-04-01
- Volume
- 4
- Issue
- 2
- Pages
- 67-73
- ISSN
- 2162-8440 (ISSN-L)
- OpenAlex
- W1549500290
- Cited by
- 7
- References
- 31
- Citations by year
- 2021: 1 · 2016: 2 · 2015: 4
- FWCI
- 1.04
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by
- Locations
- Food and public health (publishedVersion, cc-by)
- Funders
- Fundação de Amparo à Pesquisa do Estado de São Paulo (09/17234-9, 12/10685-8)
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (301301/2010-7)
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Phase Equilibria and Thermodynamics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Phytochemical Studies and Bioactivities
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry Medicinal Plant Applications
- Keywords
- 20-hydroxyecdysone, Pfaffia glomerata, Brazilian ginseng, supercritical fluid extraction, carbon dioxide extraction, ecdysteroids, medicinal plants, extraction pressure, ethanol co-solvent, extraction yield, roots
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