An introduction to modern genetics, by C.H. Waddington ...
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The term epigenetics was coined and defined by Conrad H. Waddington in the late 1930s.
“The term epigenetics was coined and also defined by Conrad H. Waddington in the late 1930s.”
From Revisiting Epigenetics Fundamentals and Its Biomedical Implications (2024) · cites this paper as [30]
Waddington defined epigenetics as the study of all the events that lead to the development of the genetic program of development.
“he stated it as “the study of all the events that lead to the development of the genetic program of development” [30]”
From Revisiting Epigenetics Fundamentals and Its Biomedical Implications (2024) · cites this paper as [30]
The epigenetic landscape is a platform for interaction of a variety of environmental factors with a complex genetic environment to change gene expression.
“the term epigenetic landscape is defined as a platform for the interaction of a variety of environmental factors with a complex genetic environment to change the expression of genes [29,30,31].”
From Revisiting Epigenetics Fundamentals and Its Biomedical Implications (2024) · cites this paper as [30]
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Das, D. N., & Ravi, N. (2022) · Environmental Research · doi:10.1016/j.envres.2022.113677 · Cited by 105 · see citing works
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Turrill, W. B. (1942) · The Botanical Review · doi:10.1007/bf02879054 · Cited by 29 · see citing works
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Maran, A. G. D. (1964) · The Journal of Laryngology & Otology · doi:10.1017/s0022215100061922 · Cited by 23 · see citing works
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Joysey, K. A. (1959) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/j.1469-185x.1959.tb01310.x · Cited by 18 · see citing works
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Silva, A. M., & Perrier, N. D. (2017) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2017.04.007 · Cited by 17 · see citing works
Gall, J. G. (2009) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.042308.113341 · Cited by 16 · see citing works
Sandon, H. (1956) · Proceedings of the Zoological Society of London · doi:10.1111/j.1096-3642.1956.tb00481.x · Cited by 16 · see citing works
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Sisken, B. F., & Gluecksohn‐Waelsch, S. (1959) · Journal of Experimental Zoology · doi:10.1002/jez.1401420129 · Cited by 15 · see citing works
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Callan, H. G. (1987) · Results and problems in cell differentiation · doi:10.1007/978-3-540-47783-9_2 · Cited by 12 · see citing works
Laubichler, M. D., & Sarkar, S. (2002) · Philosophy and medicine · doi:10.1007/978-94-010-0269-1_4 · Cited by 11 · see citing works
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Sreetharan, S., Frelon, S., Horemans, N., Laloi, P., Salomaa, S. I., & Adam‐Guillermin, C. (2023) · International Journal of Radiation Biology · doi:10.1080/09553002.2023.2281512 · Cited by 9 · see citing works
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Steffes, D. M. (2006) · Journal of the History of Biology · doi:10.1007/s10739-006-9105-5 · Cited by 40 · see citing works
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Abercrombie, M. (1967) · Novartis Foundation symposium · doi:10.1002/9780470719589.ch2 · Cited by 9 · see citing works
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Khorasani, N., Sadeghi, M., & Nowzari-Dalini, A. (2020) · PLoS ONE · doi:10.1371/journal.pone.0236519 · Cited by 7 · see citing works
Zuckerman, S. T. (1950) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/j.1469-185x.1950.tb00768.x · Cited by 7 · see citing works
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Chen, Z., Ong, C. T., & Ross, E. M. (2025) · The ISME Journal · doi:10.1093/ismejo/wraf143 · Cited by 6 · see citing works
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MacLennan, R. M., & Trueman, A. E. (1942) · Proceedings of the Royal Society of Edinburgh Section B Biology · doi:10.1017/s0080455x00011528 · Cited by 6 · see citing works
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Korzh, V. P. (2005) · BioEssays · doi:10.1002/bies.20253 · Cited by 3 · see citing works
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Painter, T. S. (1940) · Journal of the Royal Microscopical Society · doi:10.1111/j.1365-2818.1940.tb00868.x · Cited by 3 · see citing works
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Tobias, P. V. (1992) · Clinical Anatomy · doi:10.1002/ca.980050508 · Cited by 2 · see citing works
Azmi, R., Hicham, A., & Norelyaqine, A. (2021) · Advances in Science, Technology & Innovation/Advances in science, technology & innovation · doi:10.1007/978-3-030-80458-9_12 · Cited by 2 · see citing works
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SÜT, B. B. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.98866 · Cited by 1 · see citing works
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Wilkins, J. F. (2008) · Encyclopedia of Life Sciences · doi:10.1002/9780470015902.a0020811 · Cited by 1 · see citing works
Conrad Hal Waddington (1905–1975)
Hall, B. K. (2020) · Encyclopedia of Life Sciences · doi:10.1002/9780470015902.a0028954 · Cited by 1 · see citing works
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Hood, K. E. (2010) · Wiley eBooks · doi:10.1002/9781444327632.ch11
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Ryan, F. (2010) · Spektrum Akademischer Verlag eBooks · doi:10.1007/978-3-8274-2542-3_13
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- Authors
- Waddington, C. H.
- Corresponding author
- Waddington, C. H.
- Venue
- The Macmillan company eBooks
- Publisher
- The Macmillan company,
- Published
- 1939
- OpenAlex
- W2495980781
- Cited by
- 85
- References
- 0
- Citations by year
- 2025: 2 · 2024: 3 · 2023: 4 · 2022: 4 · 2021: 5 · 2020: 5 · 2019: 1 · 2018: 3 · 2017: 1 · 2016: 4 · 2015: 1 · 2014: 4 · 2013: 2 · 2012: 1
- FWCI
- 47.58
- Type
- book
- Language
- en
- Open access
- closed
- Locations
- The Macmillan company eBooks (publishedVersion)
- Biodiversity Heritage Library (Smithsonian Institution) (submittedVersion)
- Topics
- Social Sciences › Arts and Humanities › History and Philosophy of Science › Philosophy and History of Science
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Evolution and Genetic Dynamics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genetics, Bioinformatics, and Biomedical Research
- Keywords
- modern genetics, genetics, heredity (biology), gene action
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