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Cited by 313

The DOI matches its Crossref record; 60 of the 60 references it cites were found in a registry or an index.

Circular RNA: a novel biomarker and therapeutic target for human cancers

Open access
Lei, Bo, Tian, Zhiqiang, Fan, Weiping, Ni, Bing·2019·International Journal of Medical Sciences

Abstract

Circular (circ)RNAs, a newly recognized class of noncoding RNA, have been implicated in the occurrence and development of several diseases, including neurological and cardiovascular diseases. Studies of human tumors, including those of liver cancer, gastric cancer, lung cancer and colorectal cancer, have shown differential expression profiles of circRNAs, suggesting regulatory roles in cancer pathogenesis and metastasis. In this review, we discuss the most recent research into tumor-related circRNAs, providing a comprehensive summary of the expression or/and function of these circRNAs and proposing rational perspectives on the potential clinical application of circRNAs as helpful biomarkers or therapeutic targets in human tumors.

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Crossref · 10.7150/ijms.28047

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Metadata

Authors
Lei, B., Tian, Z., Fan, W., & Ni, B.
Venue
International Journal of Medical Sciences
Published
2019
Volume
16
Issue
2
Pages
292-301
ISSN
1449-1907 (ISSN-L)
OpenAlex
W2909184366
Cited by
313
References
60
FWCI
14.90
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Circular RNA: a novel biomarker and therapeutic target for human cancers. https://app.cochat.ai/papers/10.7150/ijms.28047
The paper
Lei, B., Tian, Z., Fan, W., & Ni, B. (2019). Circular RNA: a novel biomarker and therapeutic target for human cancers. International Journal of Medical Sciences. https://doi.org/10.7150/ijms.28047

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.