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U-56,407, a new antibiotic related to asukamycin: Isolation and characterization.

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Isolation and characterization of a new antibiotic U-62162.

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Alisamycin, a new antibiotic of the manumycin group. I. Taxonomy, production, isolation and biological activity.

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Manumycins E,F and G, new members of manumycin class antibiotics, from Streptomyces sp.

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Nisamycin, a new manumycin group antibiotic from Streptomyces sp. K106.

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ChemInform Abstract: New Compounds of the Manumycin Group of Antibiotics and a Facilitated Route for Their Structure Elucidation.

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TMC-95A, B, C, and D, Novel Proteasome Inhibitors Produced by Apiospora montagnei Sacc. TC 1093. Taxonomy, Production, Isolation, and Biological Activities.

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Manumycin polyketides act as molecular glues between UBR7 and P53

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The manumycin-group metabolites

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Syntheses of Natural Products Having an Epoxyquinone Structure

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Biochemical and Genetic Insights into Asukamycin Biosynthesis

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Synthetic approaches to the Manumycin A, B and C antibiotics: The first total synthesis of (+)-Manumycin A

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Selective Isolation and Distribution of Actinomadura rugatobispora Strains in Soil.

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Identification of Antimicrobial Compounds in Two Streptomyces sp. Strains Isolated From Beehives

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TMC-86A, B and TMC-96, New Proteasome Inhibitors from Streptomyces sp. TC 1084 and Saccharothrix sp. TC 1094. I. Taxonomy, Fermentation, Isolation, and Biological Activities.

Koguchi, Y., Kohno, J., Suzuki, S., NISHIO, M., Takahashi, K., Ohnuki, T., & Komatsubara, S. (1999) · The Journal of Antibiotics · doi:10.7164/antibiotics.52.1069 · Cited by 37 · see citing works

Biosynthesis of Colabomycin E, a New Manumycin‐Family Metabolite, Involves an Unusual Chain‐Length Factor

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Establishment and Use of Gellan Gum Media for Selective Isolation and Distribution Survey of Specific Rare Actinomycetes.

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Atmospheric Precipitations, Hailstone and Rainwater, as a Novel Source of Streptomyces Producing Bioactive Natural Products

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Selective isolation and distribution of the genus Planomonospora in soils

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TMC-135A and B, New Triene-ansamycins, Produced by Streptomyces sp.

NISHIO, M., Kohno, J., Sakurai, M., SUZUKI, S.-I., OKADA, N., Kawano, K., & Komatsubara, S. (2000) · The Journal of Antibiotics · doi:10.7164/antibiotics.53.724 · Cited by 24 · see citing works

Bioactive Natural Products in Actinobacteria Isolated in Rainwater From Storm Clouds Transported by Western Winds in Spain

Sarmiento-Vizcaíno, A., Martı́n, J., Reyes, F., García, L. A., & Blanco, G. (2021) · Frontiers in Microbiology · doi:10.3389/fmicb.2021.773095 · Cited by 22 · see citing works

TMC-69, a New Antitumor Antibiotic with Cdc25A Inhibitory Activity, Produced by Chrysosporium sp. TC1068.

Hirano, N., Kohno, J., Tsunoda, S., NISHIO, M., Kishi, N., Okuda, T., Kawano, K., Komatsubara, S., & NAKANISHI, N. (2001) · The Journal of Antibiotics · doi:10.7164/antibiotics.54.421 · Cited by 21 · see citing works

Natural‐Product‐Inspired Aminoepoxybenzoquinones Kill Members of the Gram‐Negative Pathogen Salmonella by Attenuating Cellular Stress Response

Mandl, F. A. M., Kirsch, V. C., Uǧur, İ., Kunold, E., Vomacka, J., Fetzer, C., Schneider, S., Richter, K., Fuchs, T. M., Antes, I., et al. (2016) · Angewandte Chemie International Edition · doi:10.1002/anie.201607338 · Cited by 18 · see citing works

Selective isolation and study on the global distribution of the genus Planobispora in soils

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TMC-169, a New Antibiotic of the Aspochalasin Group Produced by Aspergillus flavipes.

Kohno, J., NONAKA, N., NISHIO, M., Ohnuki, T., Kawano, K., Okuda, T., & Komatsubara, S. (1999) · The Journal of Antibiotics · doi:10.7164/antibiotics.52.575 · Cited by 16 · see citing works

Genomic and Untargeted Metabolomic Analysis of Secondary Metabolites in the Streptomyces griseoaurantiacus Strain MH191 Shows Media-Based Dependency for the Production of Bioactive Compounds with Potential Antifungal Activity

Ramarajan, M., Devilla, R., Dow, L., Walsh, N., Mead, O., Zakeel, M. C. M., Gallart, M., Richardson, A. E., & Thatcher, L. F. (2024) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.4c04989 · Cited by 15 · see citing works

Selective isolation and study on the global distribution of the genus Planobispora in soils

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New Type II Manumycins Produced by Streptomyces nodosus ssp. asukaensis and Their Biosynthesis.

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Isolation and characterization of N98-1272 A, B and C, selective acetylcholinesterase inhibitors from metabolites of an actinomycete strain

Zheng, Z., Dong, Y., Zhang, H., Lu, X., Ren, X. D., Zhao, G., He, J., & Si, S. (2007) · Journal of Enzyme Inhibition and Medicinal Chemistry · doi:10.1080/14756360600988781 · Cited by 12 · see citing works

The first total synthesis of a type II manumycin antibiotic, (+)-TMC-1 A: the total syntheses of (−)-LL-C10037β and (+)-manumycin B

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Microbiological Aspects of Unique, Rare, and Unusual Fatty Acids Derived from Natural Amides and Their Pharmacological Profile

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Tandem Enzymatic Oxygenations in Biosynthesis of Epoxyquinone Pharmacophore of Manumycin-type Metabolites

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Unsaturated fatty acids and a prenylated tryptophan derivative from a rare actinomycete of the genus Couchioplanes

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Antitumor activity of asukamycin, a secondary metabolite from the actinomycete bacterium Streptomyces nodosus subspecies asukaensis

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Stereoselectively synthesis and structural confirmation of dehydrodipeptides with dehydrobutyrine

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Screening of Red Sea- and Mediterranean Sea-derived Actinomycetes for Antimicrobial and Antitumor activities: LC-ESI-HRMS-based Metabolomics Study

Abdel-Razik, M. A., Azmy, A. F., Dishisha, T., EL-Gendy, A. O., Afzan, A., Kamal, N., Tawfike, A., & Sebak, M. (2025) · Microbial Cell Factories · doi:10.1186/s12934-025-02759-0 · Cited by 5 · see citing works

Discovery of anti-MRSA carpatamides' congeners by heterologous expression along with their mechanism investigation targeting FabI and biofilm formation

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Convergent synthesis of Carpatamide-A: Cytotoxic arylamine derivative from marine derived Streptomyces sp.

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Manumycin Polyketides Act as Molecular Glues Between UBR7 and P53 to Impair Breast Cancer PathogenicityPreprint

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Naturstoffbasierte Aminoepoxybenzochinone inhibieren das Wachstum verschiedener Serovare des Gram‐negativen Krankheitserregers Salmonella durch Abschwächen der bakteriellen Stressabwehr

Mandl, F. A. M., Kirsch, V. C., Uǧur, İ., Kunold, E., Vomacka, J., Fetzer, C., Schneider, S., Richter, K., Fuchs, T. M., Antes, I., et al. (2016) · Angewandte Chemie · doi:10.1002/ange.201607338 · Cited by 3 · see citing works

Evaluation of Cell Death Potential of Lepidium sativum Seed Extracts in MCF-7 Cells and Molecular Docking-based Correlation of Identified Bioactive Components with Human Caspase-6 Protein

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Manumycin from a new Streptomyces strain shows antagonistic effect against methicillin-resistant Staphylococcus aureus (MRSA)/vancomycin-resistant enterococci (VRE) strains from Korean Hospitals

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ChemInform Abstract: TMC‐1 A, B, C, and D, New Antibiotics of the Manumycin Group Produced by Streptomyces sp. Taxonomy, Production, Isolation, Physico‐Chemical Properties, Structure Elucidation, and Biological Properties.

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The Inhibitory Effect of Manumycin A on Extracellular Vesicles: What Do We Know So Far?

Abramowicz, A. (2026) · Biology of the Cell · doi:10.1111/boc.70081

ChemInform Abstract: TMC‐1 A, B, C, and D, New Antibiotics of the Manumycin Group Produced by Streptomyces sp. Taxonomy, Production, Isolation, Physico‐Chemical Properties, Structure Elucidation, and Biological Properties.

KOHNO, J., NISHIO, M., Kawano, K., NAKANISHI, N., SUZUKI, S., Uchida, T., & Komatsubara, S. (1997) · ChemInform · doi:10.1002/chin.199725226

TMC-135A and B, New Triene-ansamycins, Produced by Streptomyces sp.

NISHIO, M., Kohno, J., Sakurai, M., SUZUKI, S.-I., OKADA, N., Kawano, K., & Komatsubara, S. (2000) · The Journal of Antibiotics · doi:10.7164/antibiotics.53.724 · Cited by 24 · see citing works

Cytotoxic manumycin class antibiotic from Streptomyces sp. MCHS-4

Ha, S. C., Kim, Y. H., & Lee, J. J. (1995) · KRIBB Repository

TMC-69, a New Antitumor Antibiotic with Cdc25A Inhibitory Activity, Produced by Chrysosporium sp. TC1068.

Hirano, N., Kohno, J., Tsunoda, S., NISHIO, M., Kishi, N., Okuda, T., Kawano, K., Komatsubara, S., & NAKANISHI, N. (2001) · The Journal of Antibiotics · doi:10.7164/antibiotics.54.421 · Cited by 21 · see citing works

Manumycins E,F and G, new members of manumycin class antibiotics, from Streptomyces sp.

Shu, Y., Huang, X. S., WANG, R. R., Lam, K. S., Klohr, S. E., Volk, K. J., PIRNIK, D. M., WELLS, J. S., FERNANDES, P. B., & Patel, P. S. (1994) · The Journal of Antibiotics · doi:10.7164/antibiotics.47.324 · Cited by 21 · see citing works