The manumycin-group metabolites
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IsoTOP-ABPP is a well-validated method for covalent ligand target identification.
“prior to further processing using a well-validated method for covalent ligand target identification—isotopic tandem orthogonal proteolysis ABPP (isoTOP-ABPP) 2,17,26.”
From Manumycin polyketides act as molecular glues between UBR7 and P53 (2020) · cites this paper as [17]
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Antitumor compounds from marine actinomycetes
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Manumycin polyketides act as molecular glues between UBR7 and P53
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- Authors
- Sattler, I., Thiericke, R., & Zeeck, A.
- Affiliations
- Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI) (DE)
- Venue
- Natural Product Reports
- Publisher
- Royal Society of Chemistry (RSC)
- Published
- 1998
- Volume
- 15
- Issue
- 3
- Pages
- 221
- ISSN
- 0265-0568 (ISSN-L)
- 1460-4752
- OpenAlex
- W2059279550
- Cited by
- 95
- References
- 120
- Citations by year
- 2026: 2 · 2024: 4 · 2023: 3 · 2022: 6 · 2021: 3 · 2020: 4 · 2019: 1 · 2018: 4 · 2017: 2 · 2016: 5 · 2015: 3 · 2014: 4 · 2013: 8 · 2012: 6
- FWCI
- 0.48
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Natural Product Reports (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pharmacology › Microbial Natural Products and Biosynthesis
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bioactive Natural Diterpenoids Research
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Bioactive Compounds and Antitumor Agents
- Keywords
- manumycin, macrolide antibiotics, natural product biosynthesis
- MeSH terms
- Animals, Anti-Bacterial Agents, Carbohydrate Sequence, Insecticides, Molecular Sequence Data, Polyenes, Structure-Activity Relationship, Mice, Polyunsaturated Alkamides
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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