The DOI matches its Crossref record.
Opportunistic Infections and Immune Deficiency in Homosexual Men
Abstract
A syndrome of opportunistic infections and acquired immune deficiency occurred among four previously healthy homosexual men. Fever, leukopenia, and diminished delayed hypersensitivity were accompanied by various degrees of proctitis, perianal ulcerations, and lymphadenopathy. The infectious agents included Pneumocystis carinii, Cryptococcus neoformans, Candida albicans, herpes simplex virus, and cytomegalovirus. The immune deficiency was characterized as a persistent and profound selective decrease in the function as well as number of T lymphocytes of the helper/inducer subset and a possible activation of the suppressor/cytotoxic subset. Three patients died despite aggressive anti-infective therapy.
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Cited by
KOVACS, J. A., HIEMENZ, J. W., MACHER, A. M., STOVER, D., MURRAY, H. W., SHELHAMER, J., LANE, H. C., URMACHER, C., HONIG, C., LONGO, D. L., et al. (1984) · Annals of Internal Medicine · doi:10.7326/0003-4819-100-5-663 · Cited by 855
Murray, H. W., Rubin, B. Y., Masur, H., & Roberts, R. B. (1984) · New England Journal of Medicine · doi:10.1056/nejm198404053101404 · Cited by 513
Alsina, A., Mason, M., Uphoff, R. A., Riggsby, W. S., Becker, J. M., & Murphy, D. (1988) · Journal of Clinical Microbiology · doi:10.1128/jcm.26.4.621-624.1988 · Cited by 44
Metadata
- Authors
- MILDVAN, D., MATHUR, U., ENLOW, R. W., ROMAIN, P. L., WINCHESTER, R. J., COLP, C., SINGMAN, H., ADELSBERG, B. R., & SPIGLAND, I.
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 1982-06-01
- Volume
- 96
- Issue
- 6_Part_1
- Pages
- 700-704
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2038807049
- Cited by
- 377
- References
- 0
- FWCI
- 51.05
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Opportunistic Infections and Immune Deficiency in Homosexual Men. https://app.cochat.ai/papers/10.7326/0003-4819-96-6-700
- The paper
- MILDVAN, D., MATHUR, U., ENLOW, R. W., ROMAIN, P. L., WINCHESTER, R. J., COLP, C., SINGMAN, H., ADELSBERG, B. R., & SPIGLAND, I. (1982). Opportunistic Infections and Immune Deficiency in Homosexual Men. Annals of Internal Medicine. https://doi.org/10.7326/0003-4819-96-6-700
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
