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Cited by 217

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Sensitivity of Routine Clinical Criteria for Diagnosing Myocardial Infarction Within 24 Hours of Hospitalization

LEE, THOMAS H., ROUAN, GREGORY W., WEISBERG, MONICA C., BRAND, DONALD A., COOK, E. FRANCIS, ACAMPORA, DENISE, GOLDMAN, LEE·1987·Annals of Internal Medicine

Abstract

Myocardial infarction was diagnosed in 431 (30%) of 1460 patients with acute chest pain who had serial enzyme testing after admission to intensive or intermediate care units at three teaching and three community hospitals. The diagnosis was made within 12 hours of admission in 331 (77%) patients and within 24 hours in 415 (96%). Of the 16 patients with myocardial infarction who did not have enzyme abnormalities within 24 hours, 9 (56%) had recurrent ischemic pain during this 24-hour period. Of 451 patients who had neither enzyme abnormalities nor recurrent ischemic pain in the first 24 hours, only 7 (2%) ultimately met diagnostic criteria for myocardial infarction. These findings were prospectively validated in an independent testing set of 275 patients with myocardial infarction, 271 (99%) of whom either met diagnostic criteria for myocardial infarction or had recurrent ischemic pain within 24 hours of admission. These data suggest that 24 hours is nearly always a sufficient period to exclude myocardial infarction in patients without recurrent chest pain.

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Metadata

Authors
LEE, T. H., ROUAN, G. W., WEISBERG, M. C., BRAND, D. A., COOK, E. F., ACAMPORA, D., & GOLDMAN, L.
Venue
Annals of Internal Medicine
Published
1987-02-01
Volume
106
Issue
2
Pages
181-186
ISSN
  • 0003-4819 (ISSN-L)
  • 1539-3704
OpenAlex
W2086588667
Cited by
217
References
1
FWCI
12.21
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Sensitivity of Routine Clinical Criteria for Diagnosing Myocardial Infarction Within 24 Hours of Hospitalization. https://app.cochat.ai/papers/10.7326/0003-4819-106-2-181
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LEE, T. H., ROUAN, G. W., WEISBERG, M. C., BRAND, D. A., COOK, E. F., ACAMPORA, D., & GOLDMAN, L. (1987). Sensitivity of Routine Clinical Criteria for Diagnosing Myocardial Infarction Within 24 Hours of Hospitalization. Annals of Internal Medicine. https://doi.org/10.7326/0003-4819-106-2-181

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