CoChat
Sign Up
Cited by 309Gastrointestinal motility and disordersInfant Health and DevelopmentPsychosomatic Disorders and Their Treatments

The DOI matches its Crossref record; 106 of the 106 references it cites were found in a registry or an index.

The Irritable Bowel Syndrome: Review and a Graduated Multicomponent Treatment Approach

Drossman, Douglas A., Thompson, W. Grant·1992·Annals of Internal Medicine
DOI 10.7326/0003-4819-116-12-1009
Open this paper in CoChat — free account

Abstract

The irritable bowel syndrome is a common chronic disorder having a broad clinical spectrum of severity. Although only a small proportion of those afflicted seek medical help for their symptoms, a subset have severe and intractable symptoms. A positive diagnosis should be established from the history and physical examination; endoscopic and radiologic investigations should be minimized. We suggest that the physician also assess the severity of the illness based on its symptomatic and functional features and the patient's behavioral response. Classifying the disorder in this manner permits a graduated treatment approach that emphasizes education, reassurance, and dietary adjustment for mild symptoms. Moderate symptom severity requires, in addition, identification and modification of factors exacerbating symptoms, psychotherapeutic and behavioral techniques and, if a certain symptom type predominates, pharmacologic agents directed toward the presumed gastrointestinal motor dysfunction. For severe symptoms, physician-based behavior modification and psychopharmacologic agents are helpful. When the disorder is intractable, referral may be needed, for example, to a pain treatment center. In all cases, the skillful physician must ensure continued psychosocial support to enhance coping and continued focus on the palliative aspects of care rather than on cure.

Overview

Integrity signals

Registry

Crossref · 10.7326/0003-4819-116-12-1009

Cites

106 of 106 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Verification

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Citations

Cites

Show all 105 references

Research works printed but not linked: 26

  1. Voltaire . In: Strauss MB; ed. Familiar Medical Quotations. Boston: Little Brown and Co.; 1968:394.
  2. Drossman D, 1990, Gastroenterol Int., 3, 159
  3. Thompson W, 1986, Can Med Assoc J., 134, 111
  4. Bommelaer G, 1986, Gastroenterol Clin Biol., 10, 7
  5. Bi-zhen W, 1988, Chinese J Epid., 9, 345
  6. Segal I, 1984, S Afr Med J., 65, 73
  7. Mendis B, 1982, Ceylon Med J., 27, 171
  8. Pimparkar B, 1970, J Ind Med Assn., 54, 95
  9. Cumming W, 1849, Lond Med Gazette., 9, 969
  10. Read N, 1987, Irritable Bowel Syndrome: Pathogenesis and Treatment., 7
  11. Klein K, 1990, Semin Gastro Dis., 1, 43
  12. Melzack R, The Psychology of Pain., 1986, 1
  13. Thompson W, 1986, Am J Gastroenterol., 81, 95
  14. Thompson W, 1989, Gastroenterol Int., 2, 92
  15. Thompson W, 1992, Gastroenterol Int.
  16. Chaudhary N, 1962, Q J Med., 31, 307
  17. Drossman D, 1991, Gastroenterol Int., 4, 77
  18. Burns D, 1986, S Afr Med J., 70, 91
  19. Verhoef M, 1990, Can Med Assoc J., 142, 121
  20. Zwetchkenbaum J, 1988, Am J Gastroenterol., 83, 901
  21. Heaton K, 1985, Irritable Bowel Syndrome., 203
  22. Shimberg E, 1988, Relief from IBS.
  23. 10.1056/NEJM197804202981604 · DOI
  24. Narducci F, 1985, Am J Gastroenterol., 80, 317
  25. Hameroff S, 1984, J Clin Psychiatry., 45, 47
  26. Mcintosh D, 1992, Am J Gastroenterol.

Cited by

Sorted by citations

See all 309

Related

Metadata

Authors
Drossman, D. A., & Thompson, W. G.
Affiliations
University of North Carolina at Chapel Hill (US)
ORCID
Venue
Annals of Internal Medicine
Publisher
American College of Physicians
Published
1992-06-15
Volume
116
Issue
12_Part_1
Pages
1009-1016
ISSN
  • 0003-4819 (ISSN-L)
  • 1539-3704
DOI
10.7326/0003-4819-116-12-1009
OpenAlex
W2072613337
Cited by
309
References
105
Citations by year
2025: 2 · 2024: 4 · 2023: 7 · 2022: 1 · 2021: 2 · 2020: 2 · 2019: 6 · 2018: 3 · 2017: 7 · 2016: 5 · 2015: 5 · 2014: 4 · 2013: 8 · 2012: 9
FWCI
4.31
Type
journal article
Language
en
Open access
closed
Locations
  • Annals of Internal Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Health and Development
  • Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
Keywords
irritable bowel syndrome, symptom severity classification, dietary change, psychotherapy, behavior change, psychopharmacology, gastrointestinal motility, psychosocial support, palliative care
MeSH terms
Colonic Diseases, Functional, Combined Modality Therapy, Constipation, Diarrhea, Humans, Psychotherapy, Pain Management

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review