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The Irritable Bowel Syndrome: Review and a Graduated Multicomponent Treatment Approach
Abstract
The irritable bowel syndrome is a common chronic disorder having a broad clinical spectrum of severity. Although only a small proportion of those afflicted seek medical help for their symptoms, a subset have severe and intractable symptoms. A positive diagnosis should be established from the history and physical examination; endoscopic and radiologic investigations should be minimized. We suggest that the physician also assess the severity of the illness based on its symptomatic and functional features and the patient's behavioral response. Classifying the disorder in this manner permits a graduated treatment approach that emphasizes education, reassurance, and dietary adjustment for mild symptoms. Moderate symptom severity requires, in addition, identification and modification of factors exacerbating symptoms, psychotherapeutic and behavioral techniques and, if a certain symptom type predominates, pharmacologic agents directed toward the presumed gastrointestinal motor dysfunction. For severe symptoms, physician-based behavior modification and psychopharmacologic agents are helpful. When the disorder is intractable, referral may be needed, for example, to a pain treatment center. In all cases, the skillful physician must ensure continued psychosocial support to enhance coping and continued focus on the palliative aspects of care rather than on cure.
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“Clinical guidelines recommend that IBS patients should be referred to psychological treatments if they show anxiety, activity disruption or poor coping strategies [7,57].”
Citations
Cites
Towards positive diagnosis of the irritable bowel.
Manning, A. P., Thompson, W., Heaton, K. W., & Morris, A. F. (1978) · BMJ · doi:10.1136/bmj.2.6138.653 · Cited by 1,404
Self-citationSexual and physical abuse in women with functional or organic gastrointestinal disorders
Drossman, D. A., Leserman, J., Nachman, G., Li, Z., Gluck, H., Toomey, T. C., & Mitchell, C. M. (1990) · Annals of Internal Medicine · doi:10.7326/0003-4819-113-11-828 · Cited by 898
Self-citationPsychosocial Factors in the Irritable Bowel Syndrome
Drossman, D. A., McKee, D. C., Sandler, R. S., Mitchell, C. M., Cramer, E. M., Lowman, B. C., & Burger, A. L. (1988) · Gastroenterology · doi:10.1016/s0016-5085(88)80017-9 · Cited by 757
Self-citationBowel Patterns Among Subjects Not Seeking g Health Care
Drossman, D. A., Sandler, R. S., McKee, D. C., & Lovitz, A. J. (1982) · Gastroenterology · doi:10.1016/s0016-5085(82)80186-8 · Cited by 711
Self-citationFunctional bowel disorders in apparently healthy people
Thompson, W., & Heaton, K. W. (1980) · Gastroenterology · doi:10.1016/0016-5085(80)90142-0 · Cited by 654
Self-citationTolerance for Rectosigmoid Distention in Irritable Bowel Syndrome
Whitehead, W. E., Holtkötter, B., Enck, P., Hoelzl, R., Holmes, K. D., Anthony, J. C., Shabsin, H. S., & Schuster, M. M. (1990) · Gastroenterology · doi:10.1016/0016-5085(90)90332-u · Cited by 592
Chaudhary, N. A., & Truelove, S. C. (1962) · QJM · doi:10.1093/oxfordjournals.qjmed.a066971 · Cited by 498
Symptoms of Psychologic Distress Associated With Irritable Bowel Syndrome
Whitehead, W. E., Bosmajian, L., Zonderman, A. B., Costa Jr., P. T., & Schuster, M. M. (1988) · Gastroenterology · doi:10.1016/s0016-5085(88)80018-0 · Cited by 480
A controlled trial of psychological treatment for the irritable bowel syndrome
Guthrie, E., Creed, F. H., Dawson, D., & Tomenson, B. (1991) · Gastroenterology · doi:10.1016/0016-5085(91)90215-7 · Cited by 461
A Patient Questionnaire to Identify Bowel Disease
Talley, N. J., Phillips, S. F., Melton, L. J., Wiltgen, C., & Zinsmeister, A. R. (1989) · Annals of Internal Medicine · doi:10.7326/0003-4819-111-8-671 · Cited by 444
Research works printed but not linked: 26
- Voltaire . In: Strauss MB; ed. Familiar Medical Quotations. Boston: Little Brown and Co.; 1968:394.
- Drossman D, 1990, Gastroenterol Int., 3, 159
- Thompson W, 1986, Can Med Assoc J., 134, 111
- Bommelaer G, 1986, Gastroenterol Clin Biol., 10, 7
- Bi-zhen W, 1988, Chinese J Epid., 9, 345
- Segal I, 1984, S Afr Med J., 65, 73
- Mendis B, 1982, Ceylon Med J., 27, 171
- Pimparkar B, 1970, J Ind Med Assn., 54, 95
- Cumming W, 1849, Lond Med Gazette., 9, 969
- Read N, 1987, Irritable Bowel Syndrome: Pathogenesis and Treatment., 7
- Klein K, 1990, Semin Gastro Dis., 1, 43
- Melzack R, The Psychology of Pain., 1986, 1
- Thompson W, 1986, Am J Gastroenterol., 81, 95
- Thompson W, 1989, Gastroenterol Int., 2, 92
- Thompson W, 1992, Gastroenterol Int.
- Chaudhary N, 1962, Q J Med., 31, 307
- Drossman D, 1991, Gastroenterol Int., 4, 77
- Burns D, 1986, S Afr Med J., 70, 91
- Verhoef M, 1990, Can Med Assoc J., 142, 121
- Zwetchkenbaum J, 1988, Am J Gastroenterol., 83, 901
- Heaton K, 1985, Irritable Bowel Syndrome., 203
- Shimberg E, 1988, Relief from IBS.
- 10.1056/NEJM197804202981604 · DOI
- Narducci F, 1985, Am J Gastroenterol., 80, 317
- Hameroff S, 1984, J Clin Psychiatry., 45, 47
- Mcintosh D, 1992, Am J Gastroenterol.
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The functional gastrointestinal disorders and the Rome III process
Drossman, D. A. (2006) · Gastroenterology · doi:10.1053/j.gastro.2006.03.008 · Cited by 2,416
Self-citationAGA technical review on irritable bowel syndrome.
Drossman, D. A., Camilleri, M., Mayer, E. A., & Whitehead, W. E. (2002) · Gastroenterology · doi:10.1053/gast.2002.37095 · Cited by 1,384
Self-citationDesign of Treatment Trials for Functional Gastrointestinal Disorders
Irvine, E. J., Tack, J., Crowell, M. D., Gwee, K. A., Ke, M., Schmulson, M. J., Whitehead, W. E., & Spiegel, B. (2016) · Gastroenterology · doi:10.1053/j.gastro.2016.02.010 · Cited by 550
(2011) · Springer eBooks · doi:10.1007/springerreference_44317 · Cited by 549
Nobaek, S., Johansson, M.-L., Molin, G., Ahrné, S., & Jeppsson, B. (2000) · American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.02015.x · Cited by 653
Treatment of functional gastrointestinal disorders with antidepressant medications: a meta-analysis
Jackson, J. L., O’Malley, P. G., Tomkins, G., Balden, E., Santoro, J., & Kroenke, K. (2000) · The American Journal of Medicine · doi:10.1016/s0002-9343(99)00299-5 · Cited by 466
Müller-Lissner, S. A., Fumagalli, I. A. L., Bardhan, K. D., Pace, F., Pecher, E., Nault, B., & Rüegg, P. C. (2001) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.2001.01094.x · Cited by 462
Jamieson, D. J., & Steege, J. F. (1996) · Obstetrics and Gynecology · doi:10.1016/0029-7844(95)00360-6 · Cited by 439
Tibble, J. A., Sigthorsson, G., Foster, F., Forgács, I., & Bjarnason, I. (2002) · Gastroenterology · doi:10.1053/gast.2002.34755 · Cited by 437
Pharmacologic Treatment of the Irritable Bowel Syndrome
Jailwala, J., Imperiale, T. F., & Kroenke, K. (2000) · Annals of Internal Medicine · doi:10.7326/0003-4819-133-2-200007180-00013 · Cited by 374
“Antidepressants are purported to be beneficial and often are used in patients with chronic refractory symptoms, who are known to have a higher prevalence of psychiatric disturbances (96).”
BackgroundInfluentialFunctional gastrointestinal disorders as a public health problem
Talley, N. J. (2008) · Neurogastroenterology & Motility · doi:10.1111/j.1365-2982.2008.01097.x · Cited by 291
Role of serotonin in the pathophysiology of the irritable bowel syndrome
Crowell, M. D. (2004) · British Journal of Pharmacology · doi:10.1038/sj.bjp.0705762 · Cited by 289
Review article: irritable bowel syndrome
Camilleri, M., & Choi, M. (1997) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.1997.84256000.x · Cited by 287
Design of Treatment Trials for Functional Gastrointestinal Disorders
Irvine, E. J., Whitehead, W. E., Chey, W. D., Matsueda, K., Shaw, M., Talley, N. J., & Veldhuyzen van Zanten, S. J. O. (2006) · Gastroenterology · doi:10.1053/j.gastro.2005.11.058 · Cited by 286
Richard Locke, G., Weaver, A. L., Joseph Melton, L., & Talley, N. J. (2004) · American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2004.04043.x · Cited by 278
“These findings have led to the current dogma that psychological distress is unlikely to be causally linked to IBS but rather is a primary driver of health-care seeking (40, 41).”
BackgroundIrritable bowel syndrome: A clinical review
Soares, R. L. (2014) · World Journal of Gastroenterology · doi:10.3748/wjg.v20.i34.12144 · Cited by 266
International Survey of Patients With IBS
Drossman, D. A., Morris, C. B., Wanta, S. E., Hu, Y., Norton, N. J., Norton, W. F., Weinland, S. R., Dalton, C. B., Leserman, J., & Bangdiwala, S. I. (2009) · Journal of Clinical Gastroenterology · doi:10.1097/mcg.0b013e318189a7f9 · Cited by 235
Self-citationHorwitz, B. J., & Fisher, R. S. (2001) · New England Journal of Medicine · doi:10.1056/nejm200106143442407 · Cited by 235
Severity in Irritable Bowel Syndrome: A Rome Foundation Working Team Report
Drossman, D. A., Chang, L., Bellamy, N., Gallo-Torres, H. E., Lembo, A., Mearin, F., Norton, N. J., & Whorwell, P. (2011) · American Journal of Gastroenterology · doi:10.1038/ajg.2011.201 · Cited by 226
Self-citationMeta‐analysis: the treatment of irritable bowel syndrome
Pantoflickova, D., Michetti, P., Fried, M., Beglinger, C., & Blum, A. L. (2004) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2004.02267.x · Cited by 223
Costs of care for irritable bowel syndrome patients in a health maintenance organization
Levy, R. L., Korff, M. V., Whitehead, W. E., Stang, P., Saunders, K. W., Jhingran, P. M., Barghout, V. E., & Feld, A. D. (2001) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2001.05258.x · Cited by 205
Asian consensus on irritable bowel syndrome
Gwee, K., Bak, Y., Ghoshal, U. C., Gonlachanvit, S., Lee, O. Y., Fock, K. M., Chua, A. S. B., Lu, C., Goh, K., Kositchaiwat, C., et al. (2010) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.2010.06353.x · Cited by 172
Sexual and Physical Abuse and Gastrointestinal Illness
Drossman, D. A. (1995) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529509107768 · Cited by 168
Self-citationDo psychosocial factors define symptom severity and patient status in irritable bowel syndrome?
Drossman, D. A. (1999) · The American Journal of Medicine · doi:10.1016/s0002-9343(99)00081-9 · Cited by 168
Self-citationNon-invasive investigation of inflammatory bowel disease
Tibble, J. A. (2001) · World Journal of Gastroenterology · doi:10.3748/wjg.v7.i4.460 · Cited by 167
Psychosensory modulation of colonic sensation in the human transverse and sigmoid colon
Ford, M. J., Camilleri, M., Zinsmeister, A. R., & Hanson, R. B. (1995) · Gastroenterology · doi:10.1016/0016-5085(95)90743-2 · Cited by 167
Drossman, D. A., Li, Z., Toner, B. B., Diamant, N. E., Creed, F. H., Thompson, D. G., Read, N. W., Babbs, C., Barreiro, M. A., Bank, L., et al. (1995) · Digestive Diseases and Sciences · doi:10.1007/bf02064187 · Cited by 165
Self-citationHeymann-Monnikes, I., Arnold, R., Florin, I., Herda, C., Melfsen, S., & Monnikes, H. (2000) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.01937.x · Cited by 169
“The medical treatment was composed of two major constituents, namely a supportive physician-patient relationship (50, 51) and symptom-oriented pharmacotherapy (52–56).”
BackgroundClouse, R. E., Lustman, P. J., GEISMAN, R. A., & Alpers, D. (1994) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.1994.tb00308.x · Cited by 163
Alexithymia as Predictor of Treatment Outcome in Patients with Functional Gastrointestinal Disorders
Porcelli, P., Bagby, R. M., Taylor, G. J., Carne, M. D., Leandro, G., & Todarello, O. (2003) · Psychosomatic Medicine · doi:10.1097/01.psy.0000089064.13681.3b · Cited by 159
An Association of Serotonin with Pain Disorders and Its Modulation by Estrogens
Paredes, S., Cantillo, S., Candido, K. D., & Knežević, N. N. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20225729 · Cited by 172
“Consequently, the treatment of this condition is a challenge, with no current universal standard treatment [48].”
BackgroundWhat determines severity among patients with painful functional bowel disorders?
Drossman, D. A., Whitehead, W. E., Toner, B. B., Diamant, N. E., Hu, Y., Bangdiwala, S. I., & Jia, H. (2000) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.01936.x · Cited by 152
“clinical dimension, the severity of the pain reported (3, 4, 17).”
BackgroundSelf-citationGwee, K.-A., Wee, S., Wong, M.-L., & J C Png, D. (2004) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2004.04161.x · Cited by 190
“First, we could extrapolate that this group may represent those with milder symptoms who do not consult doctors (42).”
Backgroundvan Tilburg, M. A. L., Palsson, O. S., & Whitehead, W. E. (2013) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2013.03.004 · Cited by 154
“Psychological factors appear to play particularly important roles as moderators of symptom severity, symptom persistence, decisions to seek treatment, and response to treatment [2–4], but it is not clear which psychological factors are the most important in explaining these outcomes.”
BackgroundWalker, E. A., Katon, W. J., Jemelka, R. P., & Roy-Byrne, P. P. (1992) · The American Journal of Medicine · doi:10.1016/0002-9343(92)90133-v · Cited by 195
Chronic fatigue: symptom and syndrome
Wessely, S. (2001) · Annals of Internal Medicine · doi:10.7326/0003-4819-134-9_part_2-200105011-00007 · Cited by 136
“Patients with the irritable bowel syndrome may more be sensitive to gastrointestinal discomfort from a variety of sources (45).”
BackgroundSleep Disturbance Influences Gastrointestinal Symptoms in Women with Irritable Bowel Syndrome
Jarrett, M. E., Heitkemper, M. M., Cain, K. C., Burr, R. L., & Hertig, V. L. (2000) · Digestive Diseases and Sciences · doi:10.1023/a:1005581226265 · Cited by 139
Lynn, R. B., & Friedman, L. S. (1993) · New England Journal of Medicine · doi:10.1056/nejm199312233292608 · Cited by 139
Ljótsson, B., Andersson, G., Andersson, E., Hedman, E., Lindfors, P., Andréewitch, S., Rück, C., & Lindefors, N. (2011) · BMC Gastroenterology · doi:10.1186/1471-230x-11-110 · Cited by 132
“Clinical guidelines recommend that IBS patients should be referred to psychological treatments if they show anxiety, activity disruption or poor coping strategies [7,57].”
BackgroundClinical trial: asimadoline in the treatment of patients with irritable bowel syndrome
Mangel, A. W., Bornstein, J. D., Hamm, L. R., Buda, J. J., Wang, J., Irish, W. D., & Urso, D. M. (2008) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2008.03730.x · Cited by 136
Review article: an integrated approach to the irritable bowel syndrome
Drossman, D. A. (1999) · Alimentary Pharmacology & Therapeutics · doi:10.1046/j.1365-2036.1999.0130s2003.x · Cited by 130
Self-citationDiagnosis and management of IBS
Khan, S., & Chang, L. (2010) · Nature Reviews Gastroenterology &Hepatology · doi:10.1038/nrgastro.2010.137 · Cited by 147
Levy, R. L., Cain, K. C., Jarrett, M. E., & Heitkemper, M. M. (1997) · Journal of Behavioral Medicine · doi:10.1023/a:1025582728271 · Cited by 131
Alexithymia and Functional Gastrointestinal Disorders
Porcelli, P., Taylor, G. J., Bagby, R. M., & Carne, M. D. (1999) · Psychotherapy and Psychosomatics · doi:10.1159/000012342 · Cited by 126
Stenner, P. H. D., Dancey, C. P., & Watts, S. (2000) · Social Science & Medicine · doi:10.1016/s0277-9536(99)00475-x · Cited by 132
Hamm, L. R., Sorrells, S. C., Harding, J., Northcutt, A. R., Heath, A. T., Kapke, G. F., Hunt, C. M., & Mangel, A. W. (1999) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.1999.01077.x · Cited by 126
Antidepressants for functional gastrointestinal syndromes
Clouse, R. E. (1994) · Digestive Diseases and Sciences · doi:10.1007/bf02087651 · Cited by 124
Epstein, R. M., Quill, T. E., & McWhinney, I. R. (1999) · Archives of Internal Medicine · doi:10.1001/archinte.159.3.215 · Cited by 123
A controlled evaluation of group cognitive therapy in the treatment of irritable bowel syndrome
Blanchard, E. B., Lackner, J. M., Sanders, K., Krasner, S., Keefer, L., Payne, A., Gudleski, G. D., Katz, L., Rowell, D., Sykes, M., et al. (2007) · Behaviour Research and Therapy · doi:10.1016/j.brat.2006.07.003 · Cited by 121
Self-management for women with irritable bowel syndrome
Heitkemper, M. M., Jarrett, M. E., Levy, R. L., Cain, K. C., Burr, R. L., Feld, A., Barney, P., & Weisman, P. (2004) · Clinical Gastroenterology and Hepatology · doi:10.1016/s1542-3565(04)00242-3 · Cited by 119
Medical and lay views of irritable bowel syndrome
Dixon‐Woods, M., & Critchley, S. (2000) · Family Practice · doi:10.1093/fampra/17.2.108 · Cited by 118
Ringel, Y., Sperber, A. D., & Drossman, D. A. (2001) · Annual Review of Medicine · doi:10.1146/annurev.med.52.1.319 · Cited by 117
Self-citationEvidence-Based Management of Chronic Pelvic Pain
Reiter, R. C. (1998) · Clinical Obstetrics & Gynecology · doi:10.1097/00003081-199806000-00023 · Cited by 115
THE EPIDEMIOLOGY OF FUNCTIONAL GASTROINTESTINAL DISORDERS IN NORTH AMERICA
Locke, G. R. (1996) · Gastroenterology Clinics of North America · doi:10.1016/s0889-8553(05)70362-9 · Cited by 113
The association of sexual abuse with pelvic pain complaints in a primary care population
Jamieson, D. J., & Steege, J. F. (1997) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(97)70083-8 · Cited by 106
Muscarinic receptor ligands and their therapeutic potential
Eglen, R. M., Choppin, A., Dillon, M. P., & Hegde, S. S. (1999) · Current Opinion in Chemical Biology · doi:10.1016/s1367-5931(99)80063-5 · Cited by 104
Irritable Bowel Syndrome: Toward an Understanding of Severity
Lembo, A. J., Ameen, V. Z., & Drossman, D. A. (2005) · Clinical Gastroenterology and Hepatology · doi:10.1016/s1542-3565(05)00157-6 · Cited by 103
Self-citationPalsson, O. S., & Drossman, D. A. (2005) · Gastroenterology Clinics of North America · doi:10.1016/j.gtc.2005.02.004 · Cited by 99
Self-citationChang, L., Berman, S., Mayer, E. A., Suyenobu, B., Derbyshire, S., Naliboff, B., Vogt, B., FitzGerald, L., & Mandelkern, M. A. (2003) · American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2003.07478.x · Cited by 122
Review article: functional dyspepsia—should treatment be targeted on disturbed physiology?
Talley, N. J. (1995) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.1995.tb00359.x · Cited by 99
Symptom relief with amitriptyline in the Irritable Bowel syndrome
Rajagopalan, M., Kurian, G. P., & John, J. K. (1998) · Journal of Gastroenterology and Hepatology · doi:10.1111/j.1440-1746.1998.tb00723.x · Cited by 98
Vicario, M., Alonso, C., Guilarte, M., Serra, J., Martínez, C., González-Castro, A. M., Lobo, B., Antolín, M., Andreu, A. L., García-Arumí, E., et al. (2012) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2011.05.005 · Cited by 92
“Overall, there is growing clinical and epidemiological support for the key role of life events and psychological disturbances on the onset and severity of irritable bowel syndrome (IBS) (Bennett and Kellow, 2002; Solmaz et al., 2003; Whitehead et al., 1992; Nicholl et al., 2008; Drossman and Thompson, 1992).”
BackgroundGorard, D. A., Libby, G. W., & Farthing, M. J. G. (1995) · Digestive Diseases and Sciences · doi:10.1007/bf02063948 · Cited by 127
Tanum, L., & Malt, U. F. (1996) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365529609006404 · Cited by 90
The Status and Future of Acupuncture Clinical Research
Park, J., Linde, K., Manheimer, E. W., Molsberger, A. F., Sherman, K. J., Smith, C. A., Sung, J. J. �., Vickers, A. J., & Schnyer, R. N. (2008) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2008.sar-4 · Cited by 89
Blanchard, E. B., & Scharff, L. (2002) · Journal of Consulting and Clinical Psychology · doi:10.1037//0022-006x.70.3.725 · Cited by 88
Total costs of IBS: employer and managed care perspective.
Cash, B. D., Sullivan, S. D., & Barghout, V. E. (2005) · PubMed · Cited by 87
Irritable bowel syndrome: Psychosocial assessment and treatment.
Blanchard, E. B. (2001) · American Psychological Association eBooks · doi:10.1037/10393-000 · Cited by 87
Talley, N. J. (2006) · Internal Medicine Journal · doi:10.1111/j.1445-5994.2006.01217.x · Cited by 87
Empirical findings on the use of hypnosis in medicine: A critical review
Pinnell, C. M., & Covino, N. A. (2000) · International Journal of Clinical and Experimental Hypnosis · doi:10.1080/00207140008410047 · Cited by 84
“Several researchers have reported that between 20% to 80% of patients with IBS have demonstrated placebo responses to a variety of suggestions (Drossman & Thompson, 1992; Thompson, 1989).”
BackgroundPatel, P., Berčík, P., Morgan, D. G., Bolino, C., Pinto-Sánchez, M. I., Moayyedi, P., & Ford, A. C. (2015) · Scandinavian Journal of Gastroenterology · doi:10.3109/00365521.2015.1007079 · Cited by 84
“Second, it has been reported that unnecessary investigation in patients with suspected IBS may reinforce abnormal illness type behavior [6].”
BackgroundIrritable bowel syndrome: pathogenesis and management
Thompson, W. G. (1993) · The Lancet · doi:10.1016/0140-6736(93)90705-l · Cited by 81
Self-citationModulation of the gut microbiota: a focus on treatments for irritable bowel syndrome
Harris, L. A., & Baffy, N. J. (2017) · Postgraduate Medicine · doi:10.1080/00325481.2017.1383819 · Cited by 89
“Although an older study estimated that 5% of patients had severe IBS [14], findings from subsequent studies have suggested that severe disease may affect 15–50.”
BackgroundAssessing Somatization in Functional Gastrointestinal Disorders: Integration of Different Criteria
Porcelli, P., Carne, M. D., & Fava, G. A. (2000) · Psychotherapy and Psychosomatics · doi:10.1159/000012394 · Cited by 83
MULTIDISCIPLINARY APPROACH TO CHRONIC PELVIC PAIN
Milburn, A., Reiter, R. C., & Rhomberg, A. T. (1993) · Obstetrics and Gynecology Clinics of North America · doi:10.1016/s0889-8545(21)00384-3 · Cited by 81
Cognitive-Behaviour Therapy as a Treatment for Irritable Bowel Syndrome: A Pilot Study
Boyce, P. M., Gilchrist, J., Talley, N. J., & Rose, D. T. (2000) · Australian & New Zealand Journal of Psychiatry · doi:10.1080/j.1440-1614.2000.00731.x · Cited by 80
“Further, persons suffering from IBS have high rates of comorbidity especially with anxiety and depression, particularly among those who present for treatment [12,13].”
BackgroundInfluentialThe Irritable Bowel Syndrome and Psychiatric Disorders in The Community: Is There A Link?
Talley, N. J., Howell, S. C., & Poulton, R. (2001) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2001.03741.x · Cited by 79
Hypnosis and Irritable Bowel Syndrome: A Review of Efficacy and Mechanism of Action
Tan, G., Hammond, D. C., & Gurrala, J. (2005) · American Journal of Clinical Hypnosis · doi:10.1080/00029157.2005.10401481 · Cited by 76
“They are indicated especially for motivated patients who are able to associate their symptoms with stressors (Drossman & Thompson, 1992).”
BackgroundSallon, S., Ben‐Arye, E., Davidson, R., Shapiro, H., Ginsberg, G. M., & Ligumsky, M. (2002) · Digestion · doi:10.1159/000064936 · Cited by 75
The relationship between psychosocial parameters and outcome in irritable bowel syndrome
Creed, F. H. (1999) · The American Journal of Medicine · doi:10.1016/s0002-9343(99)00083-2 · Cited by 73
Gastrointestinal complaints among subjects with depressive symptoms in the general population
Hillilä, M. T., HÄMÄLÄINEN, J., Heikkinen, M. E., & Färkkilä, M. A. (2008) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2008.03771.x · Cited by 70
Irritable Bowel Syndrome Symptom Patterns: Frequency, Duration, and Severity
Hahn, B. A., Watson, M., Yan, S., Gunput, D., & Heuijerjans, J. (1998) · Digestive Diseases and Sciences · doi:10.1023/a:1026663613695 · Cited by 70
Hahn, B. A., Saunders, W. B., & Maier, W. C. (1997) · Digestive Diseases and Sciences · doi:10.1023/a:1018889318063 · Cited by 70
Jarrett, M. E., Heitkemper, M. M., Cain, K. C., Tuftin, M., Walker, E. A., Bond, E. F., & Levy, R. L. (1998) · Nursing Research · doi:10.1097/00006199-199805000-00006 · Cited by 69
Whole-gut transit scintigraphy in the evaluation of small-bowel and colon transit disorders.
Maurer, A. H., & Krevsky, B. (1995) · Seminars in nuclear medicine · doi:10.1016/s0001-2998(95)80006-9 · Cited by 65
Guagnozzi, D., Arias, Á., & Lucendo, A. J. (2016) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.13573 · Cited by 68
Sperber, A. D., Carmel, S., Atzmon, Y., Weisberg, I., Shalit, Y., Neumann, L., Fich, A., Friger, M., & Buskila, D. (2000) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2000.01977.x · Cited by 88
“Although not a declared objective of the index developers, the FBDSI could have potential applications for clinicians planning treatment strategies for IBS patients, as different therapeutic approaches have been recommended for patients with varying degrees of illness severity (4).”
BackgroundSydora, M. J., Sydora, B. C., & Fedorak, R. N. (2011) · Journal of Crohn s and Colitis · doi:10.1016/j.crohns.2011.08.008 · Cited by 66
Updates on treatment of irritable bowel syndrome
Hammerle, C. W., & Surawicz, C. M. (2008) · World Journal of Gastroenterology · doi:10.3748/wjg.14.2639 · Cited by 65
Paterson, W. G., Thompson, W., Vanner, S., Faloon, T., Rosser, W. W., Birtwhistle, R., Morse, J. L., & Touzel, T. A. (1999) · Europe PMC (PubMed Central) · Cited by 64
Self-citationDoes a Physically Active Lifestyle Improve Symptoms in Women With Irritable Bowel Syndrome?
Lustyk, M. K. B., Jarrett, M. E., Bennett, J. C., & Heitkemper, M. M. (2001) · Gastroenterology Nursing · doi:10.1097/00001610-200105000-00007 · Cited by 61
“…antidepressants) as well as non-pharmacological treatments such as cognitive-behavioral therapy, hypnosis, diet manipulation, stress management, and exercise (Drossman & Thompson, 1992; Levy, Cain, Jarrett, & Heitkemper, 1997; Spollett, 1989; Whitehead, Crowell, Robinson, Heller, & Schuster, 1992).”
Glende, M., Morselli‐Labate, A. M., Battaglia, G., & Evangelista, S. (2002) · European Journal of Gastroenterology & Hepatology · doi:10.1097/00042737-200212000-00008 · Cited by 61
Leandro, G. (1998) · Scandinavian Journal of Gastroenterology · doi:10.1080/00365529850171819 · Cited by 61
Porcelli, P., Affatati, V., Bellomo, A., Carne, M. D., Todarello, O., & Taylor, G. J. (2004) · Psychotherapy and Psychosomatics · doi:10.1159/000075539 · Cited by 57
Lee, C.-T., Chuang, T., Lu, C.-L., Chen, C., Chang, F.-Y., & Lee, S. (1998) · Digestive Diseases and Sciences · doi:10.1023/a:1018848122993 · Cited by 56
“Actually, the presence of a psychiatric disorde r has been one of several factors that causes an IBS nonpatient to seek medical care (31).”
BackgroundSchneider, M. A., & Fletcher, P. C. (2008) · International Journal of Nursing Practice · doi:10.1111/j.1440-172x.2008.00677.x · Cited by 55
Doctor–patient interaction for irritable bowel syndrome in primary care
Dhaliwal, S. K., & Hunt, R. H. (2004) · European Journal of Gastroenterology & Hepatology · doi:10.1097/00042737-200411000-00013 · Cited by 55
Irritable bowel syndrome and diet
Portincasa, P., Bonfrate, L., de Bari, O., Lembo, A. J., & Ballou, S. (2017) · Gastroenterology report · doi:10.1093/gastro/gow047 · Cited by 57
Stress and Visceral Perception
Delvaux, M. M. (1999) · Canadian Journal of Gastroenterology and Hepatology · doi:10.1155/1999/235916 · Cited by 55
Pothoulakis, C., Castagliuolo, I., & Leeman, S. E. (1998) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1998.tb09602.x · Cited by 55
Metadata
- Authors
- Drossman, D. A., & Thompson, W. G.
- Affiliations
- University of North Carolina at Chapel Hill (US)
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 1992-06-15
- Volume
- 116
- Issue
- 12_Part_1
- Pages
- 1009-1016
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2072613337
- Cited by
- 309
- References
- 105
- Citations by year
- 2025: 2 · 2024: 4 · 2023: 7 · 2022: 1 · 2021: 2 · 2020: 2 · 2019: 6 · 2018: 3 · 2017: 7 · 2016: 5 · 2015: 5 · 2014: 4 · 2013: 8 · 2012: 9
- FWCI
- 4.31
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Infant Health and Development
- Health Sciences › Medicine › Psychiatry and Mental health › Psychosomatic Disorders and Their Treatments
- Keywords
- irritable bowel syndrome, symptom severity classification, dietary change, psychotherapy, behavior change, psychopharmacology, gastrointestinal motility, psychosocial support, palliative care
- MeSH terms
- Colonic Diseases, Functional, Combined Modality Therapy, Constipation, Diarrhea, Humans, Psychotherapy, Pain Management
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