The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Legal, Financial, and Public Health Consequences of HIV Contamination of Blood and Blood Products in the 1980s and 1990s
Abstract
Ensuring the safety of the blood supply connects politics and science. The business and service sectors share responsibility for the collection and processing of blood donations, and government agencies perform regulatory and surveillance roles. The onset of the AIDS epidemic has challenged the interface among these systems, leading to widespread fears about compromised safety of the blood supply. Because of public concern about blood-supply decisions made in the 1980s, developed countries in the 1990s established reimbursement programs for persons with transfusion-acquired viral infections from blood or blood products, adopted diagnostic tests and procedures that improved the safety of the blood supply, and held criminal judicial investigations of government officials and industry leaders accused of delaying implementation of potential blood-safety measures. In contrast, developing countries continue to struggle with blood-supply safety issues. This paper summarizes the current status of these safety concerns in developed countries, where viral transmission from contaminated blood or blood products is extremely rare, and in developing countries, where up to 10% of HIV infections result from transfusion of blood or blood products.
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“In the early 1980's, unknowingly contaminated therapeutic proteins from human plasma caused widespread transmission of viruses, such as human immunodeficiency virus (HIV), to people with haemophilia who received these treatments 5,6 .”
From Viral contamination in biologic manufacture and implications for emerging therapies (2020) · cites this paper as [6]
Citations
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Cited by
Sorted by citations
Viral contamination in biologic manufacture and implications for emerging therapies
Barone, P. W., Wiebe, M. E., Leung, J. C., Hussein, I. T. M., Keumurian, F. J., Bouressa, J., Brussel, A., Chen, D., Chong, M., Dehghani, H., et al. (2020) · Nature Biotechnology · doi:10.1038/s41587-020-0507-2 · Cited by 212
Metadata
- Authors
- Weinberg, P. D., Hounshell, J., Sherman, L. A., Godwin, J., Ali, S., Tomori, C., & Bennett, C. L.
- Affiliations
- Northwestern University (US)
- From the Veterans Affairs Chicago Healthcare System-Lakeside Division, the Robert H. Lurie Comprehensive Cancer Center, and Northwestern University, Chicago, Illinois; and the Mid-West Center for Health Services and Policy Research and The Cardinal Bernardin Cancer Center, Loyola University School of Medicine, Maywood, Illinois.
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 2002-02-19
- Volume
- 136
- Issue
- 4
- Pages
- 312-319
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2156981604
- Cited by
- 75
- References
- 3
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 5 · 2022: 1 · 2021: 2 · 2020: 3 · 2019: 2 · 2017: 1 · 2016: 7 · 2015: 5 · 2013: 2 · 2012: 4
- FWCI
- 10.79
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annals of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- DigitalGeorgetown (Georgetown University Library) (submittedVersion)
- Topics
- Health Sciences › Medicine › Hematology › Blood donation and transfusion practices
- Health Sciences › Medicine › Infectious Diseases › HIV/AIDS Research and Interventions
- Health Sciences › Medicine › Hematology › Blood transfusion and management
- Keywords
- transfusion-transmitted HIV, transfusion safety, blood products, HIV/AIDS epidemic, blood donor screening, blood safety regulation, developing countries, developed countries
- MeSH terms
- Blood Donors, Blood Transfusion, Developing Countries, Health Policy, Hemophilia A, Humans, Malpractice, Politics, Safety, Social Responsibility, HIV Infections, Blood-Borne Pathogens, Developed Countries, Transfusion Reaction
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- CoChat. (2026). Citation check: Legal, Financial, and Public Health Consequences of HIV Contamination of Blood and Blood Products in the 1980s and 1990s. https://app.cochat.ai/papers/10.7326/0003-4819-136-4-200202190-00011
- The paper
- Weinberg, P. D., Hounshell, J., Sherman, L. A., Godwin, J., Ali, S., Tomori, C., & Bennett, C. L. (2002). Legal, Financial, and Public Health Consequences of HIV Contamination of Blood and Blood Products in the 1980s and 1990s. Annals of Internal Medicine. https://doi.org/10.7326/0003-4819-136-4-200202190-00011