Cited by 475Hepatitis C virus researchHealth Promotion and Cardiovascular PreventionLiver Disease Diagnosis and Treatment

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Screening for hepatitis C virus infection in adults: U.S. Preventive Services Task Force recommendation statement.

Moyer, Virginia A.·2013·Annals of Internal Medicine

DOI 10.7326/0003-4819-159-5-201309030-00672

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Abstract

DESCRIPTION: Update of the 2004 U.S. Preventive Services Task Force (USPSTF) recommendation on screening for and treatment of hepatitis C virus (HCV) infection in asymptomatic adults. METHODS: The Agency for Healthcare Research and Quality commissioned 2 systematic reviews on screening for and treatment of HCV infection in asymptomatic adults, focusing on evidence gaps identified in the previous USPSTF recommendation and new studies published since 2004. The evidence on screening for HCV in pregnant women was also considered. POPULATION: This recommendation applies to all asymptomatic adults without known liver disease or functional abnormalities. RECOMMENDATION: The USPSTF recommends screening for HCV infection in persons at high risk for infection. The USPSTF also recommends offering 1-time screening for HCV infection to adults born between 1945 and 1965. (B recommendation).

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Diagnosis, management, and treatment of hepatitis C: An update # † ‡
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“This recommendation was supported by the US Preventive Services Task Force in 2013.(10) Since 2013, screening programs targeting baby boomers have shown success.”
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“However, USPSTF now supports screening in those at high risk (Grade B), previously considered optional, and also birth cohort screening.(10) The primary aim of our study was to report the long-term benefit of HCV therapy in an American urban population with a high proportion of difficult-to-treat patients who were fol…”
Method
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“Birth cohort screening as recommended by the US CDC and USPSTF [4, 5] is already being implemented in large healthcare systems and is likely to increase awareness of HCV among those who are infected.”
Method
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“Furthermore, in the year 2013, Centers for Disease Control and Prevention (CDC) and the U.S. Preventive Service Task Force (USPSTF) both recommended a one-time HCV screening for all individuals born between 1945 and 1965 [70, 76].”
Background
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“Preventive Services Task Force (USPSTF) expanded testing recommendations to include all individuals born from 1945 to 1965—in addition to testing those with exposure risks or clinical indications of infection (Moyer, 2013; Smith et al., 2012).”
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Authors: Moyer, V. A.
Affiliations: United States Preventive Services Task Force (US)
Corresponding author: Moyer, Virginia A.
ORCID: Moyer, Virginia A.
Venue: Annals of Internal Medicine
Publisher: American College of Physicians
Published: 2013-09
Volume: 159
Issue: 5
Pages: 349-357
ISSN: 0003-4819 (ISSN-L)
1539-3704
DOI: 10.7326/0003-4819-159-5-201309030-00672
OpenAlex: W2148959572
Cited by: 475
References: 18
Citations by year: 2026: 2 · 2025: 11 · 2024: 5 · 2023: 8 · 2022: 21 · 2021: 23 · 2020: 40 · 2019: 50 · 2018: 59 · 2017: 57 · 2016: 68 · 2015: 59 · 2014: 52 · 2013: 19
FWCI: 41.16
Type: journal article
Language: en
Open access: closed
Licence: www.acpjournals.org/journal/aim/text-and-data-mining (tdm)
Locations: Annals of Internal Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Hepatology › Hepatitis C virus research
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
Health Sciences › Medicine › Hepatology › Liver Disease Diagnosis and Treatment
Keywords: hepatitis C virus, HCV screening, asymptomatic adults, vulnerable populations, hepatitis C treatment, baby boomers, screening guidelines
MeSH terms: Adult, Age Factors, Antiviral Agents, Female, Humans, Mass Screening, Pregnancy, Pregnancy Complications, Infectious, Cost of Illness, Risk Assessment, Hepatitis C, Chronic, Early Diagnosis, Asymptomatic Diseases

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Screening for hepatitis C virus infection in adults: U.S. Preventive Services Task Force recommendation statement.

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