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Pulmonary Function: Relation to Aging, Cigarette Habit, and Mortality: The Framingham Study
Abstract
The relation of pulmonary function to aging and cigarette habits has been examined cross sectionally and longitudinally in the Framingham cohort. On cross-sectional analysis, women were found to have lower forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV-1) values than men even after adjusting for height. Their FEV-1 percent was, on the other hand, higher than those of men. As the population aged over 10 years, their FVC and FEV-1 declined 9% to 27% depending upon age and sex. The FEV-1 percent, however, showed a decline only in the older age groups. In a cross-sectional analysis, cigarette smoking showed an inverse association to FVC and FEV-1 percent. Longitudinally, cigarette smokers showed a more rapid decline in FVC in 10 years than nonsmokers. On giving up smoking their FVC became more like that of the nonsmokers. A striking relation of FVC to mortality was noted in both sexes, which is not accounted for by associated cigarette habits.
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Cited by
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Gauderman, W. J., Avol, E., Gilliland, F., Vora, H., Thomas, D., Berhane, K., McConnell, R., Kuenzli, N., Lurmann, F., Rappaport, E., et al. (2004) · New England Journal of Medicine · doi:10.1056/nejmoa040610 · Cited by 1,440
The Effects of a Smoking Cessation Intervention on 14.5-Year Mortality: A Randomized Clinical Trial
Anthonisen, N. R., Skeans, M. A., Wise, R. A., Manfreda, J., Kanner, R. E., Connett, J. E., & for the Lung Health Study Research Group* (2005) · Annals of Internal Medicine · doi:10.7326/0003-4819-142-4-200502150-00005 · Cited by 1,237
Camilli, A. E., Burrows, B., Knudson, R. J., Lyle, S. K., & Lebowitz, M. D. (1987) · American Review of Respiratory Disease · doi:10.1164/arrd.1987.135.4.794 · Cited by 347
Marijuana Use, Respiratory Symptoms, and Pulmonary Function: A Systematic Review and Meta-analysis
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Cigarette Smoke Particle-Induced Lung Injury and Iron Homeostasis
Ghio, A. J., Pavlisko, E. N., Roggli, V. L., Todd, N. W., & Sangani, R. G. (2022) · International Journal of Chronic Obstructive Pulmonary Disease · doi:10.2147/copd.s337354 · Cited by 19
Metadata
- Authors
- ASHLEY, F., KANNEL, W. B., SORLIE, P. D., & MASSON, R.
- Venue
- Annals of Internal Medicine
- Publisher
- American College of Physicians
- Published
- 1975-06-01
- Volume
- 82
- Issue
- 6
- Pages
- 739-745
- ISSN
- 0003-4819 (ISSN-L)
- 1539-3704
- OpenAlex
- W2009596490
- Cited by
- 213
- References
- 0
- FWCI
- 2.73
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Pulmonary Function: Relation to Aging, Cigarette Habit, and Mortality: The Framingham Study. https://app.cochat.ai/papers/10.7326/0003-4819-82-6-739
- The paper
- ASHLEY, F., KANNEL, W. B., SORLIE, P. D., & MASSON, R. (1975). Pulmonary Function: Relation to Aging, Cigarette Habit, and Mortality: The Framingham Study. Annals of Internal Medicine. https://doi.org/10.7326/0003-4819-82-6-739
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