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The DOI matches its Crossref record; 44 of the 44 references it cites were found in a registry or an index.

Obesity and Mortality Among Patients Diagnosed With COVID-19: Results From an Integrated Health Care Organization

Open access
Tartof, Sara Y., Qian, Lei, Hong, Vennis, Wei, Rong, Nadjafi, Ron F., Fischer, Heidi, Li, Zhuoxin, Shaw, Sally F., Caparosa, Susan L., Nau, Claudia L., Saxena, Tanmai, Rieg, Gunter K., Ackerson, Bradley K., Sharp, Adam L., Skarbinski, Jacek, Naik, Tej K., Murali, Sameer B.·2020·Annals of Internal Medicine

Abstract

BACKGROUND: Obesity, race/ethnicity, and other correlated characteristics have emerged as high-profile risk factors for adverse coronavirus disease 2019 (COVID-19)-associated outcomes, yet studies have not adequately disentangled their effects. OBJECTIVE: To determine the adjusted effect of body mass index (BMI), associated comorbidities, time, neighborhood-level sociodemographic factors, and other factors on risk for death due to COVID-19. DESIGN: Retrospective cohort study. SETTING: Kaiser Permanente Southern California, a large integrated health care organization. PATIENTS: Kaiser Permanente Southern California members diagnosed with COVID-19 from 13 February to 2 May 2020. MEASUREMENTS: Multivariable Poisson regression estimated the adjusted effect of BMI and other factors on risk for death at 21 days; models were also stratified by age and sex. RESULTS: had relative risks of 2.68 (95% CI, 1.43 to 5.04) and 4.18 (CI, 2.12 to 8.26), respectively. This risk was most striking among those aged 60 years or younger and men. Increased risk for death associated with Black or Latino race/ethnicity or other sociodemographic characteristics was not detected. LIMITATION: Deaths occurring outside a health care setting and not captured in membership files may have been missed. CONCLUSION: Obesity plays a profound role in risk for death from COVID-19, particularly in male patients and younger populations. Our capitated system with more equalized health care access may explain the absence of effect of racial/ethnic and socioeconomic disparities on death. Our data highlight the leading role of severe obesity over correlated risk factors, providing a target for early intervention. PRIMARY FUNDING SOURCE: Roche-Genentech.

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Metadata

Authors
Tartof, S. Y., Qian, L., Hong, V., Wei, R., Nadjafi, R. F., Fischer, H., Li, Z., Shaw, S. F., Caparosa, S. L., Nau, C. L., Saxena, T., Rieg, G. K., Ackerson, B. K., Sharp, A. L., Skarbinski, J., Naik, T. K., & Murali, S. B.
Venue
Annals of Internal Medicine
Published
2020-11-17
Volume
173
Issue
10
Pages
773-781
ISSN
  • 0003-4819 (ISSN-L)
  • 1539-3704
OpenAlex
W3048371719
Cited by
608
References
44
FWCI
16.30
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Obesity and Mortality Among Patients Diagnosed With COVID-19: Results From an Integrated Health Care Organization. https://app.cochat.ai/papers/10.7326/m20-3742
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Tartof, S. Y., Qian, L., Hong, V., Wei, R., Nadjafi, R. F., Fischer, H., Li, Z., Shaw, S. F., Caparosa, S. L., Nau, C. L., Saxena, T., Rieg, G. K., Ackerson, B. K., Sharp, A. L., Skarbinski, J., Naik, T. K., & Murali, S. B. (2020). Obesity and Mortality Among Patients Diagnosed With COVID-19: Results From an Integrated Health Care Organization. Annals of Internal Medicine. https://doi.org/10.7326/m20-3742

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.