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Cited by 427

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Temporal transcriptional response to ethylene gas drives growth hormone cross-regulation in Arabidopsis

Open access
Chang, Katherine Noelani, Zhong, Shan, Weirauch, Matthew T, Hon, Gary, Pelizzola, Mattia, Li, Hai, Huang, Shao-shan Carol, Schmitz, Robert J, Urich, Mark A, Kuo, Dwight, Nery, Joseph R, Qiao, Hong, Yang, Ally, Jamali, Abdullah, Chen, Huaming, Ideker, Trey, Ren, Bing, Bar-Joseph, Ziv, Hughes, Timothy R, Ecker, Joseph R·2013·eLife

Abstract

The gaseous plant hormone ethylene regulates a multitude of growth and developmental processes. How the numerous growth control pathways are coordinated by the ethylene transcriptional response remains elusive. We characterized the dynamic ethylene transcriptional response by identifying targets of the master regulator of the ethylene signaling pathway, ETHYLENE INSENSITIVE3 (EIN3), using chromatin immunoprecipitation sequencing and transcript sequencing during a timecourse of ethylene treatment. Ethylene-induced transcription occurs in temporal waves regulated by EIN3, suggesting distinct layers of transcriptional control. EIN3 binding was found to modulate a multitude of downstream transcriptional cascades, including a major feedback regulatory circuitry of the ethylene signaling pathway, as well as integrating numerous connections between most of the hormone mediated growth response pathways. These findings provide direct evidence linking each of the major plant growth and development networks in novel ways.

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Metadata

Authors
Chang, K. N., Zhong, S., Weirauch, M. T., Hon, G., Pelizzola, M., Li, H., Huang, S.-S. C., Schmitz, R. J., Urich, M. A., Kuo, D., Nery, J. R., Qiao, H., Yang, A., Jamali, A., Chen, H., Ideker, T., Ren, B., Bar-Joseph, Z., Hughes, T. R., & Ecker, J. R.
Venue
eLife
Published
2013-06-11
Volume
2
Pages
e00675-e00675
ISSN
2050-084X (ISSN-L)
OpenAlex
W2133009404
Cited by
427
References
4
FWCI
37.03
Type
journal article
Language
en
Open access
gold

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CoChat. (2026). Citation check: Temporal transcriptional response to ethylene gas drives growth hormone cross-regulation in Arabidopsis. https://app.cochat.ai/papers/10.7554/elife.00675
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Chang, K. N., Zhong, S., Weirauch, M. T., Hon, G., Pelizzola, M., Li, H., Huang, S.-S. C., Schmitz, R. J., Urich, M. A., Kuo, D., Nery, J. R., Qiao, H., Yang, A., Jamali, A., Chen, H., Ideker, T., Ren, B., Bar-Joseph, Z., Hughes, T. R., & Ecker, J. R. (2013). Temporal transcriptional response to ethylene gas drives growth hormone cross-regulation in Arabidopsis. eLife. https://doi.org/10.7554/elife.00675

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.