The DOI matches its Crossref record; 154 of the 154 references it cites were found in a registry or an index.
Hidden shift of the ionome of plants exposed to elevated CO2 depletes minerals at the base of human nutrition
Open accessAbstract
Mineral malnutrition stemming from undiversified plant-based diets is a top global challenge. In C3 plants (e.g., rice, wheat), elevated concentrations of atmospheric carbon dioxide (eCO2) reduce protein and nitrogen concentrations, and can increase the total non-structural carbohydrates (TNC; mainly starch, sugars). However, contradictory findings have obscured the effect of eCO2 on the ionome—the mineral and trace-element composition—of plants. Consequently, CO2-induced shifts in plant quality have been ignored in the estimation of the impact of global change on humans. This study shows that eCO2 reduces the overall mineral concentrations (−8%, 95% confidence interval: −9.1 to −6.9, p<0.00001) and increases TNC:minerals > carbon:minerals in C3 plants. The meta-analysis of 7761 observations, including 2264 observations at state of the art FACE centers, covers 130 species/cultivars. The attained statistical power reveals that the shift is systemic and global. Its potential to exacerbate the prevalence of ‘hidden hunger’ and obesity is discussed.
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2 retracted
Duval, B. D., Blankinship, J. C., Dijkstra, P., & Hungate, B. A. (2011) · Plant Ecology · doi:10.1007/s11258-011-9998-8 · Cited by 65
RetractedDuval, B. D., Blankinship, J. C., Dijkstra, P., & Hungate, B. A. (2015) · Plant Ecology · doi:10.1007/s11258-015-0541-1 · Cited by 45
RetractedR: A Language and Environment for Statistical Computing
R Core Team (2025) · doi:10.32614/r.manuals · Cited by 352,181
Faul, F., Erdfelder, E., Lang, A.-G., & Buchner, A. (2007) · Behavior Research Methods · doi:10.3758/bf03193146 · Cited by 65,971
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722
Why Most Published Research Findings Are False
Ioannidis, J. P. A. (2005) · PLoS Medicine · doi:10.1371/journal.pmed.0020124 · Cited by 10,505
‘Small Changes' to Diet and Physical Activity Behaviors for Weight Management
Hills, A. P., Byrne, N. M., Lindstrom, R., & Hill, J. O. (2013) · Obesity Facts · doi:10.1159/000345030 · Cited by 9,493
Barker, T. J., Bashmakov, I., Bernstein, L., Bogner, J. R., Bosch, P. C., Dave, R., Davidson, O., Fisher, B. S., Grubb, M. J., Gupta, S. K., et al. (2007) · Socio-Environmental Systems Modeling · Cited by 9,160
Power failure: why small sample size undermines the reliability of neuroscience
Button, K. S., Ioannidis, J. P. A., Mokrysz, C., Nosek, B. A., Flint, J., Robinson, E. S. J., & Munafò, M. R. (2013) · Nature Reviews Neuroscience · doi:10.1038/nrn3475 · Cited by 7,641 · cited 3×
“Such a small power not only raises the probability of obtaining a false negative to 90–94% but also increases the likelihood that a statistically significant result does not reflect a true effect (Button et al., 2013).”
BackgroundInfluentialThe World Health Report 2002 - Reducing Risks, Promoting Healthy Life
Not Available, N. A. (2003) · Education for Health: Change in Learning & Practice · doi:10.1080/1357628031000116808 · Cited by 6,046
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Godde, C. M., Mason-D’Croz, D., Mayberry, D. E., Thornton, P. K., & Herrero, M. (2021) · Global Food Security · doi:10.1016/j.gfs.2020.100488 · Cited by 768
Ainsworth, E. A., & Long, S. P. (2021) · Global Change Biology · doi:10.1111/gcb.15375 · Cited by 592
Zhu, C., Kobayashi, K., Loladze, I., Zhu, J., Jiang, Q., Xu, X., Liu, G., Seneweera, S., Ebi, K. L., Drewnowski, A., et al. (2018) · Science Advances · doi:10.1126/sciadv.aaq1012 · Cited by 444
Self-citationSoares, J. C., Santos, C. S., Carvalho, S. M. P., Pintado, M. M., & Vasconcelos, M. W. (2019) · Plant and Soil · doi:10.1007/s11104-019-04229-0 · Cited by 319
Farooq, M. S., Uzair, M., Raza, A., Habib, M., Xu, Y., Yousuf, M., Yang, S. H., & Ramzan Khan, M. (2022) · Frontiers in Plant Science · doi:10.3389/fpls.2022.927535 · Cited by 267
Metadata
- Authors
- Loladze, I.
- Venue
- eLife
- Publisher
- eLife Sciences Publications, Ltd
- Published
- 2014-05-07
- Volume
- 3
- Pages
- e02245-e02245
- ISSN
- 2050-084X (ISSN-L)
- OpenAlex
- W2149598896
- Cited by
- 502
- References
- 154
- FWCI
- 22.35
- Type
- journal article
- Language
- en
- Open access
- gold
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