The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Streptomyces exploration is triggered by fungal interactions and volatile signals
Open accessAbstract
It has long been thought that the life cycle of Streptomyces bacteria encompasses three developmental stages: vegetative hyphae, aerial hyphae and spores. Here, we show interactions between Streptomyces and fungi trigger a previously unobserved mode of Streptomyces development. We term these Streptomyces cells ‘explorers’, for their ability to adopt a non-branching vegetative hyphal conformation and rapidly transverse solid surfaces. Fungi trigger Streptomyces exploratory growth in part by altering the composition of the growth medium, and Streptomyces explorer cells can communicate this exploratory behaviour to other physically separated streptomycetes using an airborne volatile organic compound (VOC). These results reveal that interkingdom interactions can trigger novel developmental behaviours in bacteria, here, causing Streptomyces to deviate from its classically-defined life cycle. Furthermore, this work provides evidence that VOCs can act as long-range communication signals capable of propagating microbial morphological switches.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models
Stamatakis, A. (2006) · Bioinformatics · doi:10.1093/bioinformatics/btl446 · Cited by 15,582
Medically important bacterial-fungal interactions
Peleg, A. Y., Hogan, D. A., & Mylonakis, E. (2010) · Nature Reviews Microbiology · doi:10.1038/nrmicro2313 · Cited by 619
Carnitine metabolism to trimethylamine by an unusual Rieske-type oxygenase from human microbiota
Zhu, Y., Jameson, E., Crosatti, M., Schäfer, H., Rajakumar, K., Bugg, T. D. H., & Chen, Y. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1316569111 · Cited by 372
Claessen, D., Rink, R., de Jong, W., Siebring, J., de Vreugd, P., Boersma, F. G. H., Dijkhuizen, L., & Wösten, H. A. B. (2003) · Genes & Development · doi:10.1101/gad.264303 · Cited by 327
Elliot, M. A., Karoonuthaisiri, N., Huang, J., Bibb, M. J., Cohen, S. N., Kao, C. M., & Buttner, M. J. (2003) · Genes & Development · doi:10.1101/gad.264403 · Cited by 246
Self-citationA novel sensor of NADH/NAD+ redox poise in Streptomyces coelicolor A3(2)
Brekasis, D., & Paget, M. S. B. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg453 · Cited by 224
Bertuzzi, M., Schrettl, M., Alcazar-Fuoli, L., Cairns, T. C., Muñoz, A., Walker, L. A., Herbst, S., Safari, M., Cheverton, A. M., Chen, D., et al. (2014) · PLoS Pathogens · doi:10.1371/journal.ppat.1004413 · Cited by 158
Briard, B., Heddergott, C., & Latgé, J.-P. (2016) · mBio · doi:10.1128/mbio.00219-16 · Cited by 153
Cited by
Microbial Volatiles: Small Molecules with an Important Role in Intra- and Inter-Kingdom Interactions
Schulz-Bohm, K., Martín-Sánchez, L., & Garbeva, P. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.02484 · Cited by 448
Soil microbial diversity and composition: Links to soil texture and associated properties
Xia, Q., Rufty, T., & Shi, W. (2020) · Soil Biology and Biochemistry · doi:10.1016/j.soilbio.2020.107953 · Cited by 369
Metadata
- Authors
- Jones, S. E., Ho, L., Rees, C. A., Hill, J. E., Nodwell, J. R., & Elliot, M. A.
- Venue
- eLife
- Publisher
- eLife Sciences Publications, Ltd
- Published
- 2017-01-03
- Volume
- 6
- ISSN
- 2050-084X (ISSN-L)
- OpenAlex
- W2564833305
- Cited by
- 189
- References
- 8
- FWCI
- 12.10
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Streptomyces exploration is triggered by fungal interactions and volatile signals. https://app.cochat.ai/papers/10.7554/elife.21738
- The paper
- Jones, S. E., Ho, L., Rees, C. A., Hill, J. E., Nodwell, J. R., & Elliot, M. A. (2017). Streptomyces exploration is triggered by fungal interactions and volatile signals. eLife. https://doi.org/10.7554/elife.21738
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
