Germ cell connectivity enhances cell death in response to DNA damage in the Drosophila testis

The DNA Damage Response: Making It Safe to Play with Knives

Ciccia, A., & Elledge, S. J. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.09.019 · Cited by 4,368 · see citing works

The development of Drosophila melanogaster

Ingham, P. W. (1994) · Trends in Genetics · doi:10.1016/0168-9525(90)90017-z · Cited by 3,158 · see citing works

DEVELOPMENT IN DROSOPHILA MELANOGASTER

Li, J.-C. (1927) · Genetics · doi:10.1093/genetics/12.2.198 · Cited by 2,887 · see citing works

Regulation of zygotic gene expression in Drosophila primordial germ cells

Doren, M. V., Williamson, A., & Lehmann, R. (1998) · Current Biology · doi:10.1016/s0960-9822(98)70091-0 · Cited by 706 · see citing works

The Drosophila fusome, a germline-specific organelle, contains membrane skeletal proteins and functions in cyst formation

Lin, H., Yue, L., & Spradling, A. C. (1994) · Development · doi:10.1242/dev.120.4.947 · Cited by 527 · see citing works

Effects of chemotherapy and radiotherapy on spermatogenesis in humans

Meistrich, M. L. (2013) · Fertility and Sterility · doi:10.1016/j.fertnstert.2013.08.010 · Cited by 416 · see citing works

Genetically haploid spermatids are phenotypically diploid

Braun, R. E., Behringer, R. R., Peschon, J. J., Brinster, R. L., & Palmiter, R. D. (1989) · Nature · doi:10.1038/337373a0 · Cited by 353 · see citing works

Centrosome misorientation reduces stem cell division during ageing

Cheng, J., Türkel, N., Hemati, N., Fuller, M. T., Hunt, A. J., & Yamashita, Y. M. (2008) · Nature · doi:10.1038/nature07386 · Cited by 346 · see citing works

A Balbiani body and the fusome mediate mitochondrial inheritance duringDrosophilaoogenesis

Cox, R. T., & Spradling, A. C. (2003) · Development · doi:10.1242/dev.00365 · Cited by 319 · see citing works

The mitochondrial serine protease HtrA2/Omi: an overview

Walle, L. V., Lamkanfi, M., & Vandenabeele, P. (2008) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4402291 · Cited by 318 · see citing works

The Drosophila Ovarian and Testis Stem Cell Niches: Similar Somatic Stem Cells and Signals

Decotto, E., & Spradling, A. C. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.08.012 · Cited by 315 · see citing works

Mouse oocytes differentiate through organelle enrichment from sister cyst germ cells

Lei, L., & Spradling, A. C. (2016) · Science · doi:10.1126/science.aad2156 · Cited by 313 · see citing works

GERMLINE CYST FORMATION IN DROSOPHILA

de Cuevas, M., Lilly, M. A., & Spradling, A. C. (1997) · Annual Review of Genetics · doi:10.1146/annurev.genet.31.1.405 · Cited by 311 · see citing works

Drosophila melanogaster MNK/Chk2 and p53 Regulate Multiple DNA Repair and Apoptotic Pathways following DNA Damage

Brodsky, M. H., Weinert, B. T., Tsang, G., Rong, Y. S., McGinnis, N., Golic, K. G., Rio, D. C., & Rubin, G. M. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.3.1219-1231.2004 · Cited by 310 · see citing works

Genetic and teratogenic effects of cancer treatments on gametes and embryos

Arnon, J., Meirow, D., Lewis-Roness, H., et al. (2001) · Human Reproduction Update · doi:10.1093/humupd/7.4.394 · Cited by 308 · see citing works

The Origin of Asymmetry: Early Polarisation of the Drosophila Germline Cyst and Oocyte

Huynh, J., & Johnston, D. S. (2004) · Current Biology · doi:10.1016/j.cub.2004.05.040 · Cited by 305 · see citing works

hu-li tai shao, a gene required for ring canal formation during Drosophila oogenesis, encodes a homolog of adducin.Preprint

Yue, L., & Spradling, A. C. (1992) · Genes & Development · doi:10.1101/gad.6.12b.2443 · Cited by 288 · see citing works

DNA double-strand break-induced phosphorylation of Drosophila histone variant H2Av helps prevent radiation-induced apoptosis

Madigan, J. P. (2002) · Nucleic Acids Research · doi:10.1093/nar/gkf496 · Cited by 277 · see citing works

Assembly of ring canals in the male germ line from structural components of the contractile ring

Hime, G. R., Brill, J. A., & Fuller, M. T. (1996) · Journal of Cell Science · doi:10.1242/jcs.109.12.2779 · Cited by 277 · see citing works

Germline cysts: a conserved phase of germ cell development?

Pepling, M. E., de Cuevas, M., & Spradling, A. C. (1999) · Trends in Cell Biology · doi:10.1016/s0962-8924(99)01594-9 · Cited by 273 · see citing works

Germ Cell Intercellular BridgesPreprint

Greenbaum, M. P., Iwamori, T., Buchold, G. M., & Matzuk, M. M. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005850 · Cited by 254 · see citing works

Spermatogenesis, DNA damage and DNA repair mechanisms in male infertility

Gunes, S. O., Al-Sadaan, M., & Agarwal, A. K. (2015) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2015.06.010 · Cited by 241 · see citing works

Discovery, regulation, and action of the major apoptotic nucleases DFF40/CAD and endonuclease G

Widłak, P., & Garrard, W. T. (2005) · Journal of Cellular Biochemistry · doi:10.1002/jcb.20409 · Cited by 225 · see citing works

Structure and functions of stable intercellular bridges formed by incomplete cytokinesis during development

Haglund, K., Nezis, I. P., & Stenmark, H. (2011) · Communicative & Integrative Biology · doi:10.4161/cib.13550 · Cited by 203 · see citing works

α-spectrin is required for germline cell division and differentiation in the Drosophila ovary

de Cuevas, M., Lee, J. K., & Spradling, A. C. (1996) · Development · doi:10.1242/dev.122.12.3959 · Cited by 202 · see citing works

Drosophila Checkpoint Kinase 2 Couples Centrosome Function and Spindle Assembly to Genomic Integrity

Takada, S., Kelkar, A., & Theurkauf, W. E. (2003) · Cell · doi:10.1016/s0092-8674(03)00202-2 · Cited by 201 · see citing works

Sensitivity and Time of Degeneration of Spermatogenic Cells Irradiated in Various Stages of Maturation in the Mouse

Oakberg, E. F. (1955) · Radiation Research · doi:10.2307/3570245 · Cited by 199 · see citing works

Barriers to Male Transmission of Mitochondrial DNA in Sperm Development

DeLuca, S. Z., & O’Farrell, P. H. (2012) · Developmental Cell · doi:10.1016/j.devcel.2011.12.021 · Cited by 188 · see citing works

Structure and functions of stable intercellular bridges formed by incomplete cytokinesis during development.

Haglund, K., Nezis, I. P., & Stenmark, H. (2011) · PubMed · doi:10.4161/cib.4.1.13550 · Cited by 166 · see citing works

Alternative Germ Cell Death Pathway in Drosophila Involves HtrA2/Omi, Lysosomes, and a Caspase-9 Counterpart

Yacobi-Sharon, K., Namdar, Y., & Arama, E. (2013) · Developmental Cell · doi:10.1016/j.devcel.2013.02.002 · Cited by 119 · see citing works

Cyclin A Associates with the Fusome during Germline Cyst Formation in the Drosophila Ovary

Lilly, M. A., de Cuevas, M., & Spradling, A. C. (2000) · Developmental Biology · doi:10.1006/dbio.1999.9570 · Cited by 114 · see citing works

Genome-wide RNAi identifies p53-dependent and -independent regulators of germ cell apoptosis in C. elegans

Lettre, G., Kritikou, E. A., Jaeggi, M., Calixto, A., Fraser, A. G., Kamath, R. S., Ahringer, J., & Hengartner, M. O. (2004) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401488 · Cited by 110 · see citing works

Domains of the Pavarotti kinesin-like protein that direct its subcellular distribution: effects of mislocalisation on the tubulin and actin cytoskeleton duringDrosophilaoogenesis

Minestrini, G., Máthé, E., & Glover, D. M. (2002) · Journal of Cell Science · doi:10.1242/jcs.115.4.725 · Cited by 95 · see citing works

Chk2 regulates irradiation-induced, p53-mediated apoptosis in Drosophila

Peters, M., DeLuca, C., Hirao, A., Stambolic, V., Potter, J., Zhou, L., Silvester, J., Snow, B. E., Arya, S., Wong, J. A., et al. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.172382899 · Cited by 93 · see citing works

Drosophila HtrA2 is dispensable for apoptosis but acts downstream of PINK1 independently from Parkin

Tain, L. S., Chowdhury, R. B., Tao, R., Plun‐Favreau, H., Moisoi, N., Martins, L. M., Downward, J., Whitworth, A. J., & Tapon, N. (2009) · Cell Death and Differentiation · doi:10.1038/cdd.2009.23 · Cited by 91 · see citing works

From cyst to tubule: innovations in vertebrate spermatogenesis

Yoshida, S. (2015) · Wiley Interdisciplinary Reviews Developmental Biology · doi:10.1002/wdev.204 · Cited by 88 · see citing works

Ionizing radiation induces caspase-dependent but Chk2- and p53-independent cell death in Drosophila melanogaster

Wichmann, A., Jaklevic, B. R., & Su, T. T. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0510528103 · Cited by 87 · see citing works

Somatic cell lineage is required for differentiation and not maintenance of germline stem cells in Drosophila testes

Lim, J. G. Y., & Fuller, M. T. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1215516109 · Cited by 85 · see citing works

Drosophila melanogaster: a Model for the Study of DNA Damage Checkpoint Response

Song, Y. (2005) · Molecules and Cells · doi:10.1016/s1016-8478(23)13152-9 · Cited by 73 · see citing works

Gene Deletions by Ends-In Targeting in Drosophila melanogaster

Xie, H. B., & Golic, K. G. (2004) · Genetics · doi:10.1534/genetics.104.030882 · Cited by 61 · see citing works

Protein Equilibration Through Somatic Ring Canals in Drosophila

McLean, P., & Cooley, L. (2013) · Science · doi:10.1126/science.1234887 · Cited by 60 · see citing works

p53 activity is selectively licensed in the Drosophila stem cell compartment

Wylie, A., Lu, W.-J., D’Brot, A., Buszczak, M., & Abrams, J. (2014) · eLife · doi:10.7554/elife.01530 · Cited by 57 · see citing works

A somatic permeability barrier around the germline is essential forDrosophilaspermatogenesis

Fairchild, M. J., Smendziuk, C. M., & Tanentzapf, G. (2014) · Development · doi:10.1242/dev.114967 · Cited by 55 · see citing works

The regulated elimination of transit-amplifying cells preserves tissue homeostasis during protein starvation in <i>Drosophila</i> testis

Yang, H., & Yamashita, Y. M. (2015) · Development · doi:10.1242/dev.122663 · Cited by 55 · see citing works

Regulation of cyclin A localization downstream of Par-1 function is critical for the centrosome orientation checkpoint in Drosophila male germline stem cells

Yuan, H., Chiang, C.-Y. A., Cheng, J., et al. (2011) · Developmental Biology · doi:10.1016/j.ydbio.2011.10.010 · Cited by 53 · see citing works

Evolution of mitochondrial cell death pathway: Proapoptotic role of HtrA2/Omi in Drosophila

Igaki, T., Suzuki, Y., Tokushige, N., Aonuma, H., Takahashi, R., & Miura, M. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.03.079 · Cited by 41 · see citing works

CHECKING THE FOUNDATION: RECENT RADIOBIOLOGY AND THE LINEAR NO-THRESHOLD THEORY

Ulsh, B. A. (2010) · Health Physics · doi:10.1097/hp.0b013e3181e32477 · Cited by 37 · see citing works

The interaction of DIAP1 with dOmi/HtrA2 regulates cell death in Drosophila

Khan, F., Fujioka, M., Datta, P., Fernandes‐Alnemri, T., Jaynes, J. B., & Alnemri, E. S. (2008) · Cell Death and Differentiation · doi:10.1038/cdd.2008.19 · Cited by 29 · see citing works

Semi-permeable Diffusion Barriers Enhance Patterning Robustness in the C. elegans Germline

Cinquin, A., Zheng, L., Taylor, P. H., et al. (2015) · Developmental Cell · doi:10.1016/j.devcel.2015.10.027 · Cited by 23 · see citing works

spict, a cyst cell-specific gene, regulates starvation-induced spermatogonial cell death in the Drosophila testis

Chiang, A. C.-Y., Yang, H., & Yamashita, Y. M. (2017) · Scientific Reports · doi:10.1038/srep40245 · Cited by 23 · see citing works

Relative Biological Effectiveness of Low- and High-LET Radiotherapy Beams for Jejunal Crypt Cell Survival at Low Doses Per Fraction

Fu, K. K., Phillips, T. L., Heilbron, D. C., et al. (1979) · Radiology · doi:10.1148/132.1.205 · Cited by 22 · see citing works

The FHA domain determinesDrosophilaChk2/Mnk localization to key mitotic structures and is essential for early embryonic DNA damage responses

Takada, S., Collins, E. R., & Kurahashi, K. (2015) · Molecular Biology of the Cell · doi:10.1091/mbc.e14-07-1238 · Cited by 11 · see citing works

Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018.

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., et al. (2018) · Cell Death &amp; Differentiation · doi:10.1038/s41418-017-0012-4 · Cited by 6,680 · see citing works

Selective Determination of the Doxorubicin Content of Individual Acidic Organelles in Impure Subcellular Fractions

Chen, Y., Walsh, R. J., & Arriaga, E. A. (2005) · Analytical Chemistry · doi:10.1021/ac0480996 · Cited by 35 · see citing works

Male Germ Cell Specification in Plants

Chen, W., Wang, P., Liu, C., Han, Y., & Zhao, F. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25126643 · Cited by 5 · see citing works

Germ Cell Transplantation in Avian Species

Park, Y. H., Kim, Y., & Han, J. Y. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-9009-2_19 · Cited by 1 · see citing works

nanos1 is required to maintain oocyte production in adult zebrafish

Draper, B. W., McCallum, C. M., & Moens, C. B. (2007) · Developmental Biology · doi:10.1016/j.ydbio.2007.03.007 · Cited by 190 · see citing works

Targeting the germline-specific gene regulatory network in testicular germ cell tumours

Tang, W. W. C., Alves-Lopes, J. P., Venzor, A. C., et al. (2019) · European Urology Supplements · doi:10.1016/s1569-9056(19)32489-3