The impact of Chat Generative Pre-trained Transformer (ChatGPT) on oncology: application, expectations, and future prospects
Open accessAbstract
The integration of Chat Generative Pre-trained Transformer (ChatGPT) into the field of oncology has recently garnered significant attention, with potential implications for enhancing both research and clinical practice. This paper presents a comprehensive review of the evolving landscape of ChatGPT applications in oncology, emphasizing its contributions to diagnosis, treatment, research, and patient education. We examine its role in assisting medical professionals, researchers, and patients in understanding complex cancer-related data and making informed decisions. Ethical considerations and potential challenges associated with the implementation of ChatGPT in oncology are also discussed. This article highlights the promising role of ChatGPT as a valuable tool in the oncology domain and outlines future directions for research and application.
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AI technologies provide timely, accurate, and accessible information that can empower patients and caregivers, supporting engagement, comprehension, and autonomy throughout the cancer care continuum.
“These technologies provide timely, accurate, and accessible information that can empower patients and caregivers, supporting engagement, comprehension, and autonomy throughout the cancer care continuum [6-8].”
From Empathic AI for Patient-Centered Cancer Care: A Scoping Review of Patient Navigation, Support, and Clinical Practice (2026) · cites this paper as [7]
The Review’s “ChatGPT in cancer patient education” section describes the potential for accessible explanations that improve patients’ comprehension, and its discussion of treatment decisions says such information can support engagement. It does not establish the same benefits for caregivers or throughout the cancer care continuum. Its “Rigorous Fact-Checking” section also cautions that responses may be outdated or erroneous, so timely, accurate information cannot be assumed. (LLM, conf=0.86)
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Cites
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“ChatGPT's influence extends beyond the realm of health sciences, impacting specialized medical fields like radiology, pathology, and genomics, by simplifying complex medical terminology and facilitating effective communication with patients [6-9].”
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“This facilitates the selection of targeted therapies and helps patients and healthcare providers make informed decisions about treatment options [8,19].”
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ChatGPT, An Artificial Intelligence Chatbot, Is Impacting Medical Literature
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“By analyzing mammograms, ChatGPT can identify suspicious regions and offer insights to radiologists, potentially enhancing early diagnosis rates [12,20,21].”
Background
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Cited by
Sorted by citations
Fairness in AI-driven oncology: investigating racial and gender biases in large language models
Agrawal, A. (2024) · Cureus · doi:10.7759/cureus.69541 · Cited by 10 · see citing works
White, B. M., Aitken, G. L., Zink, J. A., Kheirkhah Rahimabad, P., Kumsa, F. A., Hashtarkhani, S., Rashid, R., Kheirinejad, S., Girdwood, T., Brett, C. L., et al. (2026) · JMIR Cancer · doi:10.2196/82336 · Cited by 2 · see citing works
- Authors
- Li, Y., Gao, W., Luan, Z., Zhou, Z., & Li, J.
- Affiliations
- Xi'an Jiaotong University (CN)
- Changzhi Medical College (CN)
- Corresponding author
- Li, Jianjun
- Venue
- Cureus
- Published
- 2023-11-11
- Volume
- 15
- Issue
- 11
- Pages
- e48670-e48670
- ISSN
- 2168-8184 (ISSN-L)
- PMC
- PMC10714025
- OpenAlex
- W4388613519
- Cited by
- 11
- References
- 9
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 8
- FWCI
- 0.13
- Type
- journal article
- Language
- en
- Open access
- diamond
- doi.org
- Licence
- cc-by
- Locations
- Cureus (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
- Physical Sciences › Computer Science › Artificial Intelligence › Artificial Intelligence Applications
- Physical Sciences › Computer Science › Artificial Intelligence › AI in cancer detection
- Keywords
- ChatGPT, large language models, oncology, cancer diagnosis, cancer therapy, cancer research, patient education, clinical decision support, ethics of AI in healthcare, artificial intelligence in healthcare
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