Cited by 130Artificial Intelligence in Healthcare and EducationAI in cancer detectionBreast Cancer Treatment Studies

Evaluating ChatGPT as an Adjunct for the Multidisciplinary Tumor Board Decision–Making in Primary Breast Cancer Cases

Open access
Lukac, Stefan, Dayan, Davut, Fink, Visnja, Leinert, Elena, Hartkopf, Andreas, Veselinovic, Kristina, Janni, Wolfgang, Rack, Brigitte +3 more·2023·Archives of Gynecology and Obstetrics

Published version of a preprint

Abstract

BACKGROUND: As the available information about breast cancer is growing every day, the decision-making process for the therapy is getting more complex. ChatGPT as a transformer-based language model possesses the ability to write scientific articles and pass medical exams. But is it able to support the multidisciplinary tumor board (MDT) in the planning of the therapy of patients with breast cancer? MATERIAL AND METHODS: We performed a pilot study on 10 consecutive cases of breast cancer patients discussed in MDT at our department in January 2023. Included were patients with a primary diagnosis of early breast cancer. The recommendation of MDT was compared with the recommendation of the ChatGPT for particular patients and the clinical score of the agreement was calculated. RESULTS: Results showed that ChatGPT provided mostly general answers regarding chemotherapy, breast surgery, radiation therapy, chemotherapy, and antibody therapy. It was able to identify risk factors for hereditary breast cancer and point out the elderly patient indicated for chemotherapy to evaluate the cost/benefit effect. ChatGPT wrongly identified the patient with Her2 1 + and 2 + (FISH negative) as in need of therapy with an antibody and called endocrine therapy "hormonal treatment". CONCLUSIONS: Support of artificial intelligence by finding individualized and personalized therapy for our patients in the time of rapidly expanding amount of information is looking for the ways in the clinical routine. ChatGPT has the potential to find its spot in clinical medicine, but the current version is not able to provide specific recommendations for the therapy of patients with primary breast cancer.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1007/s00404-023-07130-5

Cites

25 of 25 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Lukac, S., Dayan, D., Fink, V., Leinert, E., Hartkopf, A., Veselinovic, K., Janni, W., Rack, B., Pfister, K., Heitmeir, B., & Ebner, F.
Affiliations
University Hospital Ulm (DE)
Corresponding author
Lukac, Stefan
Venue
Archives of Gynecology and Obstetrics
Published
2023-07-17
Volume
308
Issue
6
Pages
1831-1844
ISSN
  • 0003-9128 (ISSN-L)
  • 1432-0711
OpenAlex
W4384558920
Cited by
130
References
23
Citations by year
2026: 32 · 2025: 44 · 2024: 45 · 2023: 9
FWCI
5.17
Type
journal article
Language
en
Open access
Locations
  • Archives of Gynecology and Obstetrics (publishedVersion, cc-by)
  • Research Square (acceptedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
Funders
Universitätsklinikum Ulm
Topics
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Physical Sciences › Computer Science › Artificial Intelligence › AI in cancer detection
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › Breast Cancer Treatment Studies
Keywords
ChatGPT, large language models, multidisciplinary tumor board, primary breast cancer, early breast cancer, treatment decision-making, clinical implementation of AI, HER2-positive breast cancer, endocrine therapy, personalized treatment
MeSH terms
Aged, Antibodies, Artificial Intelligence, Breast Neoplasms, Female, Humans, Oncogenes, Pilot Projects

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review