Effects of a Dietary Beetroot Juice Treatment on Systemic and Cerebral Haemodynamics—A Pilot Study

Vascular Contributions to Cognitive Impairment and Dementia: A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association

Gorelick, P. B., Scuteri, A., Black, S. E., DeCarli, C., Greenberg, S. M., Iadecola, C., Launer, L. J., Laurent, S., Lopez, O. L., Nyenhuis, D., et al. (2011) · Stroke · doi:10.1161/str.0b013e3182299496 · Cited by 3,811 · see citing works

Arterial stiffness, pressure and flow pulsatility and brain structure and function: the Age, Gene/Environment Susceptibility – Reykjavik Study

Mitchell, G. F., van Buchem, M. A., Sigurdsson, S. O., Gotal, J. D., Jónsdóttir, M. K., Kjartansson, Ó., García, M., Aspelund, T., Harris, T. B., Gudnason, V. G., et al. (2011) · Brain · doi:10.1093/brain/awr253 · Cited by 891 · see citing works

Inorganic Nitrate Supplementation Lowers Blood Pressure in Humans: Role for Nitrite-Derived NO

Kapil, V., Milsom, A. B., Okorie, M., Maleki-Toyserkani, S., Akram, F., Rehman, F., Arghandawi, S., Pearl, V., Benjamin, N., Loukogeorgakis, S., et al. (2010) · Hypertension · doi:10.1161/hypertensionaha.110.153536 · Cited by 621 · see citing works

Acute and chronic effects of dietary nitrate supplementation on blood pressure and the physiological responses to moderate-intensity and incremental exercise

Vanhatalo, A., Bailey, S. J., Blackwell, J. R., DiMenna, F. J., Pavey, T. G., Wilkerson, D. P., Benjamin, N., Winyard, P. G., & Jones, A. M. (2010) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00206.2010 · Cited by 529 · see citing works

Pulse Pressure and Pulse Wave Velocity Are Related to Cognitive Decline in the Baltimore Longitudinal Study of Aging

Waldstein, S. R., Rice, S. C., Thayer, J. F., Najjar, S. S., Scuteri, A., & Zonderman, A. B. (2008) · Hypertension · doi:10.1161/hypertensionaha.107.093674 · Cited by 462 · see citing works

Left ventricular compliance: Mechanisms and clinical implications

Gaasch, W. H., Levine, H. J., Quiñones, M. A., & Alexander, J. K. (1976) · The American Journal of Cardiology · doi:10.1016/s0002-9149(76)80015-x · Cited by 454 · see citing works

Influence of sex steroid hormones on cerebrovascular function

Krause, D. N., DUCKLES, S. P., & Pelligrino, D. A. (2006) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01095.2005 · Cited by 432 · see citing works

Dietary nitrate supplementation reduces the O₂cost of walking and running: a placebo-controlled study

Lansley, K. E., Winyard, P. G., Fulford, J., Vanhatalo, A., Bailey, S. J., Blackwell, J. R., DiMenna, F. J., Gilchrist, M., Benjamin, N., & Jones, A. M. (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01070.2010 · Cited by 404 · see citing works

Radial augmentation index: A useful and easily obtainable parameter for vascular aging

Kohara, K., Tabara, Y., OSHIUMI, A., MIYAWAKI, Y., Kobayashi, T., & Miki, T. (2005) · American Journal of Hypertension · doi:10.1016/j.amjhyper.2004.10.010 · Cited by 256 · see citing works

Vascular Stiffness and Increased Pulse Pressure in the Aging Cardiovascular System

Steppan, J., Barodka, V. M., Berkowitz, D. E., & Nyhan, D. P. (2011) · Cardiology Research and Practice · doi:10.4061/2011/263585 · Cited by 231 · see citing works

Enhanced Vasodilator Activity of Nitrite in Hypertension: Critical Role for Erythrocytic Xanthine Oxidoreductase and Translational Potential

Ghosh, S. M., Kapil, V., Fuentes-Calvo, I., Bubb, K. J., Pearl, V., Milsom, A. B., Khambata, R., Maleki-Toyserkani, S., Yousuf, M., Benjamin, N., et al. (2013) · Hypertension · doi:10.1161/hypertensionaha.111.00933 · Cited by 218 · see citing works

Cerebral Hemodynamics in Normal Aging: Central Artery Stiffness, Wave Reflection, and Pressure Pulsatility

Tarumi, T., Khan, M. A., Liu, J., Tseng, B. M., Parker, R. S., Riley, J. R., Tinajero, C., & Zhang, R. (2014) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2014.44 · Cited by 218 · see citing works

Blood pressure-lowering effects of beetroot juice and novel beetroot-enriched bread products in normotensive male subjects

Hobbs, D. A., Kaffa, N., George, T. W., Methven, L., & Lovegrove, J. A. (2012) · British Journal Of Nutrition · doi:10.1017/s0007114512000190 · Cited by 194 · see citing works

Dietary nitrate modulates cerebral blood flow parameters and cognitive performance in humans: A double-blind, placebo-controlled, crossover investigation

Wightman, E. L., Haskell-Ramsay, C. F., Thompson, K. G., Blackwell, J. R., Winyard, P. G., Forster, J., Jones, A. M., & Kennedy, D. O. (2015) · Physiology & Behavior · doi:10.1016/j.physbeh.2015.05.035 · Cited by 170 · see citing works

Absence of an effect of high nitrate intake from beetroot juice on blood pressure in treated hypertensive individuals: a randomized controlled trial

Bondonno, C. P., Liu, A. H., Croft, K. D., Ward, N. C., Shinde, S., Moodley, Y. P., Lundberg, J. O., Puddey, I. B., Woodman, R. J., & Hodgson, J. M. (2015) · American Journal of Clinical Nutrition · doi:10.3945/ajcn.114.101188 · Cited by 110 · see citing works

Influence of dietary nitrate supplementation on physiological and cognitive responses to incremental cycle exercise

Thompson, K. G., Turner, L., Prichard, J., Dodd, F., Kennedy, D. O., Haskell, C., Blackwell, J. R., & Jones, A. M. (2014) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2013.12.015 · Cited by 109 · see citing works

Stroke and the female brain

Bushnell, C. (2008) · Nature Clinical Practice Neurology · doi:10.1038/ncpneuro0686 · Cited by 93 · see citing works

Role of Astrocytes in Matching Blood Flow to Neuronal Activity

Jakovčević, D., & Harder, D. R. (2007) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/s0070-2153(06)79004-4 · Cited by 92 · see citing works

Neurovascular coupling in hippocampus is mediated via diffusion by neuronal-derived nitric oxide

Lourenço, C. F., Santos, R. M., Barbosa, R. M., Cadenas, E., Radí, R., & Laranjinha, J. A. N. (2014) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2014.05.021 · Cited by 89 · see citing works

Augmentation Index Derived from Peripheral Arterial Tonometry Correlates with Cardiovascular Risk Factors

Patvardhan, E. A., Heffernan, K. S., Ruan, J., Hession, M. J., Warner, P. J., Karas, R. H., & Kuvin, J. T. (2011) · Cardiology Research and Practice · doi:10.4061/2011/253758 · Cited by 80 · see citing works

Cardiac output determination by simple one-step rebreathing technique

Farhi, L. E., Nesarajah, M. S., Olszowka, A. J., Metildi, L. A., & Elus, A. K. (1976) · Respiration Physiology · doi:10.1016/0034-5687(76)90091-8 · Cited by 80 · see citing works

Cognitive Impairment Is Related to Increased Arterial Stiffness and Microvascular Damage in Patients With Never-Treated Essential Hypertension

Triantafyllidi, H., Arvaniti, C., Lekakis, J. P., Ikonomidis, I., Siafakas, N., Tzortzis, S., Trivilou, P., Zerva, L., Stamboulis, E., & Kremastinos, D. T. (2009) · American Journal of Hypertension · doi:10.1038/ajh.2009.35 · Cited by 78 · see citing works

Determinants of human cerebral pressure–flow velocity relationships: new insights from vascular modelling and Ca2+channel blockade

Tzeng, Y., Chan, G. S. H., Willie, C. K., & Ainslie, P. N. (2011) · The Journal of Physiology · doi:10.1113/jphysiol.2011.206953 · Cited by 73 · see citing works

Control of cerebrovascular patterning by neural activity during postnatal development

Lacoste, B., & Gu, C. (2015) · Mechanisms of Development · doi:10.1016/j.mod.2015.06.003 · Cited by 55 · see citing works

Effects of Dietary Nitrates on Systemic and Cerebrovascular Hemodynamics

Bond, V., Curry, B. H., Adams, R. G., Asadi, M. S., Millis, R. M., & Haddad, G. E. (2013) · Cardiology Research and Practice · doi:10.1155/2013/435629 · Cited by 49 · see citing works

Contribution of arterial Windkessel in low-frequency cerebral hemodynamics during transient changes in blood pressure

Chan, G. S. H., Ainslie, P. N., Willie, C. K., Taylor, C. E., Atkinson, G., Jones, H., Lovell, N. H., & Tzeng, Y. (2011) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01407.2010 · Cited by 49 · see citing works

Cardiorespiratory function associated with dietary nitrate supplementation

Bond, V., Curry, B. H., Adams, R. G., Millis, R. M., & Haddad, G. E. (2013) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/apnm-2013-0263 · Cited by 44 · see citing works

Effects of Nitrate Supplementation on Cardiovascular and Autonomic Reactivity in African-American Females

Bond, V., Curry, B. H., Adams, R. G., Asadi, M. S., Stancil, K. A., Millis, R. M., & Haddad, G. E. (2014) · ISRN Physiology · doi:10.1155/2014/676235 · Cited by 35 · see citing works

Differences between middle cerebral artery blood velocity waveforms of young and postmenopausal women

Kurji, A., Debert, C. T., Whitelaw, W. A., Rawling, J. M., Frayne, R., & Poulin, M. J. (2006) · Menopause The Journal of The North American Menopause Society · doi:10.1097/01.gme.0000177905.94515.24 · Cited by 24 · see citing works

Interactions Between the Genes of Vasodilatation Pathways Influence Blood Pressure and Nitric Oxide Level in Hypertension

Kumar, R., Kohli, S., Mishra, A., Garg, R., Alam, P., Stobdan, T., Nejatizadeh, A., Gupta, M. D., Tyagi, S., & Pasha, M. A. Q. (2014) · American Journal of Hypertension · doi:10.1093/ajh/hpu130 · Cited by 22 · see citing works

Nitric Oxide and Cerebrovascular Regulation

Tabatabaei, S. N., & Girouard, H. (2014) · Vitamins and hormones · doi:10.1016/b978-0-12-800254-4.00014-3 · Cited by 18 · see citing works

Non-invasive assessment of cardiac output and stroke volume in patients during exercise

Ohlsson, J. L., & Wranne, B. (1986) · European Journal of Applied Physiology · doi:10.1007/bf00421650 · Cited by 17 · see citing works

The benefits and risks of beetroot juice consumption: a systematic review

Zamani, H., de Joode, M. E. J. R., Hossein, I. J., Henckens, N. F. T., Guggeis, M. A., Berends, J. E., de Kok, T. M. C. M., & Breda, S. G. J. V. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2020.1746629 · Cited by 116 · see citing works

A comprehensive review of beetroot ( <i>Beta vulgaris</i> L.) bioactive components in the food and pharmaceutical industries

Thiruvengadam, M., Chung, I.-M., Samynathan, R., Chandar, S. R. H., Venkidasamy, B., Sarkar, T., Rebezov, M., Gorelik, O., Shariati, M. A., & Simal-Gandara, J. (2024) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2022.2108367 · Cited by 78 · see citing works

Effects of inorganic nitrate and nitrite consumption on cognitive function and cerebral blood flow: A systematic review and meta-analysis of randomized clinical trials

Clifford, T., Babateen, A. M., Shannon, O. M., Capper, T. E., Ashor, A. W., Stephan, B. C. M., Robinson, L. A., O'Hara, J. P., Mathers, J. C., Stevenson, E., et al. (2018) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1453779 · Cited by 49 · see citing works

Red beetroot extract mitigates chlorpyrifos-induced reprotoxicity associated with oxidative stress, inflammation, and apoptosis in rats

Albasher, G. I., Albrahim, T. I., Alsultan, N., Alfaraj, S., Alharthi, M. S., Kassab, R. B., & Moneim, A. E. A. (2019) · Environmental Science and Pollution Research · doi:10.1007/s11356-019-07009-6 · Cited by 37 · see citing works

Pink pressure: beetroot (Beta vulgaris rubra) as a possible novel medical therapy for chronic kidney disease

Moreira, L. D. S. G., Fanton, S., Cardozo, L., Borges, N. A., Combet, E., Shiels, P. G., Stenvinkel, P., & Mafra, D. (2021) · Nutrition Reviews · doi:10.1093/nutrit/nuab074 · Cited by 23 · see citing works

A Systematic Review of Literature on the Representation of Racial and Ethnic Minority Groups in Clinical Nutrition Interventions

Dhillon, J., Jacobs, A., Flores, S. O., & Rios, L. K. D. (2022) · Advances in Nutrition · doi:10.1093/advances/nmac002 · Cited by 20 · see citing works

Dietary nitrate supplementation and cognitive health: the nitric oxide-dependent neurovascular coupling hypothesis

Gonçalves, J. S., Marçal, A. L., Marques, B. S., Costa, F. D., Laranjinha, J., Rocha, B. S., & Lourenço, C. F. (2024) · Biochemical Society Transactions · doi:10.1042/bst20230491 · Cited by 6 · see citing works

Acute beetroot juice consumption does not alter cerebral autoregulation or cardiovagal baroreflex sensitivity during lower-body negative pressure in healthy adults

Worley, M. L., Reed, E. L., Chapman, C. L., Kueck, P. J., Seymour, L., Fitts, T., Zazulak, H. E., Schlader, Z. J., & Johnson, B. D. (2023) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2023.1115355 · Cited by 3 · see citing works

Dietary Nitrate-Rich Vegetables as Natural Modulators of Health: Mechanisms and Benefits in Ageing Populations

Kurhaluk, N., Kołodziejska, R., Buyun, L., Kamiński, P., & Tkaczenko, H. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27083461 · Cited by 3 · see citing works

Red Beetroot: Pigment Efficacy and Safety in the Context of Cancer

Coimbra, P. P. S., Teixeira, A. D. C., Brito, G. O., Lima, T. P. B., Souza, L., Felzenszwalb, I., Teodoro, A. J., & Araújo-Lima, C. F. (2026) · Nutrition Reviews · doi:10.1093/nutrit/nuag006

A pilot randomized controlled trial of the effects of dietary nitrate supplementation on dynamic cerebral autoregulation in older adults with metabolic syndrome

Gosalia, J., Spicuzza, J. M. D., Bowlus, C. K., Brinkerhoff, A., Baker, S. R., Qiu, J. J., Kim‐Shapiro, D. B., Pawelczyk, J. A., & Proctor, D. N. (2026) · Physiological Reports · doi:10.14814/phy2.71073

Modulation of cerebral blood flow parameters in humans following consumption of nitrate-rich beetroot juice

Haskell, C. F., Kennedy, D. O., Dodd, F. L., Turner, L. A., JONES, A. M., PRICHARD, J., BELL, P., & Thompson, K. (2012) · Appetite · doi:10.1016/j.appet.2012.05.069

Clinical Study Effects of Dietary Nitrates on Systemic and

Hemodynamics, C., Millis, R. M., & Haddad, G. E. (2016)

Effects of Dietary Nitrates on Systemic and Cerebrovascular Hemodynamics

Bond, V., Curry, B. H., Adams, R. G., Asadi, M. S., Millis, R. M., & Haddad, G. E. (2013) · Cardiology Research and Practice · doi:10.1155/2013/435629 · Cited by 49 · see citing works

Importance of Beetroot Juice as a Compulsory Diatry Food: The Effects of Beetroot Juice on Blood Pressure and Muscle Function

Kumar, D. S. K. D. S., & Singh, D. B. J. S. D. B. J. (2018) · Journal of Advances in Science and Technology

Effects of Nitrate Supplementation on Cardiovascular and Autonomic Reactivity in African-American Females

Bond, V., Curry, B. H., Adams, R. G., Asadi, M. S., Stancil, K. A., Millis, R. M., & Haddad, G. E. (2014) · ISRN Physiology · doi:10.1155/2014/676235 · Cited by 35 · see citing works