Tuberculosis Lymphadenitis in Ethiopia
Open accessAbstract
Tuberculosis (TB) is one of the most serious public health challenges in Ethiopia. Indeed, Ethiopia ranks 7th among 22 countries with a high burden of TB worldwide. Both pulmonary TB and extrapulmonary TB (EPTB) are issues of concern. Ethiopia ranks 3rd in terms of the number of EPTB patients worldwide, with TB lymphadenitis (TBL) being the most common. According to the World Health Organization's Global TB Report 2009, the estimated number of TB patients in Ethiopia was 314,267 in 2007, with an estimated incidence rate of 378 patients per 100,000 population. Furthermore, 36% patients suffered from EPTB, with TBL accounting for 80% of these patients. In Ethiopia, pathological services, culture, and drug susceptibility testing for mycobacterium species are not available as routine tests, not even for cases with suspected infection by drug-resistant strains. Therefore, the management of multidrug-resistant (MDR) TB in Ethiopia is currently unsatisfactory. Against this background, a high index of clinical doubt and timely use of diagnostic methods, prompt confirmation of diagnosis, and early initiation of specific anti-TB treatment are the key factors for the successful management of MDR-TB and TBL in Ethiopia.
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Specificity of Xpert MTB/RIF against composite culture was in agreement with Biadigilegn et al (69.2%).
“This is in agreement with the study done by Biadigilegn et al (specificity, 69.2%) [2].”
From Diagnostic accuracy of Xpert MTB/RIF assay and non-molecular methods for the diagnosis of tuberculosis lymphadenitis (2019) · cites this paper as [2]
The Diagnosis section discusses staining and culture but gives no Xpert MTB/RIF specificity estimate. Searches for “69.2% specificity” and “Xpert MTB/RIF” found no passage reporting the claimed comparison with composite culture. Page numbers were not available in our copy. (LLM, conf=0.76)
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“EPTB accounts for 36% of new TB cases [2].”
Background
- Authors
- Biadglegne, F., Tesfaye, W., Anagaw, B., Tessema, B., Debebe, T., Anagaw, B., Mulu, A., Sack, U., & Rodloff, A. C.
- Affiliations
- University Hospital Leipzig (DE)
- University of Gondar (ET)
- Addis Ababa University (ET)
- Faculty of Medicine and Health Sciences, Bahir Dar University
- Venue
- Japanese Journal of Infectious Diseases
- Publisher
- Editorial Committee of Japanese Journal of Infectious Diseases, National Institute of Infectious Dis
- Published
- 2013
- Volume
- 66
- Issue
- 4
- Pages
- 263-268
- ISSN
- 1344-6304 (ISSN-L)
- 1884-2836
- OpenAlex
- W2007724496
- Cited by
- 32
- References
- 40
- Citations by year
- 2025: 1 · 2024: 1 · 2023: 3 · 2022: 4 · 2021: 2 · 2020: 2 · 2019: 4 · 2018: 3 · 2017: 1 · 2016: 4 · 2015: 4 · 2014: 3
- FWCI
- 0.47
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Japanese Journal of Infectious Diseases (publishedVersion)
- PubMed (publishedVersion)
- Publikationsdatenbank der Fraunhofer-Gesellschaft (Fraunhofer-Gesellschaft) (submittedVersion)
- Fraunhofer-Publica (Fraunhofer-Gesellschaft) (submittedVersion)
- Funders
- Deutscher Akademischer Austauschdienst
- Fraunhofer-Institut für Zelltherapie und Immunologie
- Topics
- Health Sciences › Medicine › Infectious Diseases › Tuberculosis Research and Epidemiology
- Health Sciences › Medicine › Surgery › Diagnosis and treatment of tuberculosis
- Health Sciences › Medicine › Surgery › Infectious Diseases and Tuberculosis
- Keywords
- tuberculous lymphadenitis, extrapulmonary tuberculosis, multidrug-resistant tuberculosis, Ethiopia, tuberculosis incidence, tuberculosis diagnosis, drug susceptibility testing, tuberculosis treatment
- MeSH terms
- Ethiopia, Humans, Tuberculosis, Lymph Node, Incidence, Prevalence
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