Zierath, Juleen R.

Exercise Metabolism and the Molecular Regulation of Skeletal Muscle Adaptation

Egan, B., & Zierath, J. R. (2013) · Cell Metabolism

Muscle Physiology and DisordersCardiovascular and exercise physiology

Cited by 2,084

Integrative Biology of Exercise

Hawley, J. A., Hargreaves, M., Joyner, M. J., & Zierath, J. R. (2014) · Cell

Exercise and Physiological ResponsesCardiovascular and exercise physiology

Cited by 1,152

Acute Exercise Remodels Promoter Methylation in Human Skeletal Muscle

Barrès, R., Yan, J., Egan, B., Treebak, J. T., Rasmussen, M., Fritz, T., Caidahl, K., Krook, A., O'Gorman, D. J., & Zierath, J. R. (2012) · Cell Metabolism

Epigenetics and DNA MethylationMuscle Physiology and Disorders

Cited by 965

Exerkines in health, resilience and disease

Chow, L. S., Gerszten, R. E., Taylor, J. M., Pedersen, B. K., van Praag, H., Trappe, S., Febbraio, M. A., Galis, Z. S., Gao, Y., Haus, J. M., et al. (2022) · Nature Reviews Endocrinology

Exercise and Physiological ResponsesAdipokines, Inflammation, and Metabolic Diseases

Cited by 927

Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle

Cantó, C., Jiang, L. Q., Deshmukh, A. S., Mataki, C., Coste, A., Lagouge, M., Zierath, J. R., & Auwerx, J. (2010) · Cell Metabolism

Metabolism, Diabetes, and CancerSirtuins and Resveratrol in Medicine

Cited by 921

Mitofusin-2 Determines Mitochondrial Network Architecture and Mitochondrial Metabolism

Bach, D., Pich, S., Soriano, F. X., Vega, N., Baumgartner, B., Oriola, J., Daugaard, J. R., Lloberas, J., Camps, M., Zierath, J. R., et al. (2003) · Journal of Biological Chemistry

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 832

Skeletal Muscle PGC-1α1 Modulates Kynurenine Metabolism and Mediates Resilience to Stress-Induced Depression

Agudelo, L. Z., Femenía, T., Orhan, F., Porsmyr-Palmertz, M., Goiny, M., Martinez-Redondo, V., Correia, J. C., Izadi, M., Bhat, M., Schuppe-Koistinen, I., et al. (2014) · Cell

Tryptophan and brain disordersTreatment of Major Depression

Cited by 739

Tumor Necrosis Factor-α Induces Skeletal Muscle Insulin Resistance in Healthy Human Subjects via Inhibition of Akt Substrate 160 Phosphorylation

Plomgaard, P., Bouzakri, K., Krogh-Madsen, R., Mittendorfer, B., Zierath, J. R., & Pedersen, B. K. (2005) · Diabetes

Adipokines, Inflammation, and Metabolic DiseasesMetabolism, Diabetes, and Cancer

Cited by 627

Non-CpG methylation of the PGC-1α promoter through DNMT3B controls mitochondrial density.

Barrès, R., Osler, M. E., Yan, J., Rune, A., Fritz, T., Caidahl, K., Krook, A., & Zierath, J. R. (2009) · Cell Metabolism

Epigenetics and DNA MethylationMetabolism, Diabetes, and Cancer

Cited by 602

Skeletal Muscle Fiber Type: Influence on Contractile and Metabolic Properties

Zierath, J. R., & Hawley, J. A. (2004) · PLoS Biology

Muscle Physiology and DisordersCardiovascular and exercise physiology

Cited by 518

TXNIP regulates peripheral glucose metabolism in humans

Parikh, H., Carlsson, E., Chutkow, W. A., Johansson, L. E., Storgaard, H., Poulsen, P., Saxena, R., Ladd, C., Schulze, P. C., Mazzini, M. J., et al. (2007) · PLoS Medicine

Metabolism, Diabetes, and CancerAdipose Tissue and Metabolism

Cited by 495

Exercise Promotes Healthy Aging of Skeletal Muscle

Cartee, G. D., Hepple, R. T., Bamman, M. M., & Zierath, J. R. (2016) · Cell Metabolism

Muscle Physiology and DisordersNutrition and Health in Aging

Cited by 483

Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity

Pillon, N. J., Gabriel, B. M., Dollet, L., Smith, J. A. B., Sardón Puig, L., Botella, J., Bishop, D. J., Krook, A., & Zierath, J. R. (2020) · Nature Communications

Muscle Physiology and DisordersCardiovascular and exercise physiology

Cited by 457

A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

Moltke, I., Grarup, N., Jørgensen, M. E., Bjerregaard, P., Treebak, J. T., Fumagalli, M., Korneliussen, T. S., Andersen, M. A., Nielsen, T. S., Krarup, N. T., et al. (2014) · Nature

Genetic Associations and EpidemiologyDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 418

High-Fat Diet Reprograms the Epigenome of Rat Spermatozoa and Transgenerationally Affects Metabolism of the Offspring

de Castro Barbosa, T., Ingerslev, L. R., Alm, P. S., Versteyhe, S., Massart, J., Rasmussen, M., Donkin, I., Sjögren, R., Mudry, J. M., Vetterli, L., et al. (2016) · Molecular Metabolism

Birth, Development, and HealthEpigenetics and DNA Methylation

Cited by 417

Genetic Predisposition to an Impaired Metabolism of the Branched-Chain Amino Acids and Risk of Type 2 Diabetes: A Mendelian Randomisation Analysis

Lotta, L. A., Scott, R. A., Sharp, S. J., Burgess, S., Luan, J., Tillin, T., Schmidt, A. F., Imamura, F., Stewart, I. D., Perry, J. R. B., et al. (2016) · PLOS Medicine

Genetic Associations and EpidemiologyDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 417

Insulin action on glucose transport and plasma membrane GLUT4 content in skeletal muscle from patients with NIDDM

Zierath, J. R., He, L., Gumà, A., Wahlström, E. O., Klip, A., & Wallberg-Henriksson, H. (1996) · Diabetologia

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 402

Evidence that oestrogen receptor-α plays an important role in the regulation of glucose homeostasis in mice: insulin sensitivity in the liver

Bryzgalova, G., Gao, H., Ahren, B., Zierath, J. R., Galuska, D., Steiler, T. L., Dahlman-Wright, K., Nilsson, S., Gustafsson, J.-Å., Efendic, S., et al. (2006) · Diabetologia

Estrogen and related hormone effectsAdipokines, Inflammation, and Metabolic Diseases

Cited by 384

Circadian rhythms and exercise — re-setting the clock in metabolic disease

Gabriel, B. M., & Zierath, J. R. (2019) · Nature Reviews Endocrinology

Circadian rhythm and melatoninSleep and Work-Related Fatigue

Cited by 382

Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients

Krook, A., Björnholm, M., Galuska, D., Jiang, X. J., Fahlman, R., Myers, M. G., Wallberg-Henriksson, H., & Zierath, J. R. (2000) · Diabetes

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 375

Exercise intensity-dependent regulation of peroxisome proliferator-activated receptor γ coactivator-1α mRNA abundance is associated with differential activation of upstream signalling kinases in human skeletal muscle: Exercise intensity and PGC-1α regulation

Egan, B., Carson, B. P., Garcia-Roves, P. M., Chibalin, A. V., Sarsfield, F. M., Barron, N., McCaffrey, N., Moyna, N. M., Zierath, J. R., & O’Gorman, D. J. (2010) · The Journal of Physiology

Adipose Tissue and MetabolismCardiovascular and exercise physiology

Cited by 373

Expression of Mfn2, the Charcot-Marie-Tooth Neuropathy Type 2A Gene, in Human Skeletal Muscle

Bach, D., Naon, D., Pich, S., Soriano, F. X., Vega, N., Rieusset, J., Laville, M., Guillet, C., Boirie, Y., Wallberg-Henriksson, H., et al. (2005) · Diabetes

Mitochondrial Function and PathologyMuscle Physiology and Disorders

Cited by 369

Insulin action and insulin resistance in human skeletal muscle

Zierath, J. R., Krook, A., & Wallberg-Henriksson, H. (2000) · Diabetologia

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 367

Exercise Metabolism and Adaptation in Skeletal Muscle

Smith, J. A. B., Murach, K. A., Dyar, K. A., & Zierath, J. R. (2023) · Nature Reviews Molecular Cell Biology

Muscle Physiology and DisordersCardiovascular and exercise physiology

Cited by 342