Schug, Zachary T.

Targeting cancer metabolism in the era of precision oncology

Stine, Z. E., Schug, Z. T., Salvino, J. M., & Dang, C. V. (2022) · Nature Reviews Drug Discovery

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 1,189

Acetyl-CoA synthetase 2 promotes acetate utilization and maintains cancer cell growth under metabolic stress

Schug, Z. T., Peck, B., Jones, D. T., Zhang, Q., Grosskurth, S., Alam, I. S., Goodwin, L. M., Smethurst, E., Mason, S., Blyth, K., et al. (2015) · Cancer Cell

Cancer, Lipids, and MetabolismCancer, Hypoxia, and Metabolism

Cited by 820

Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate

Zhao, S., Jang, C., Liu, J., Uehara, K., Gilbert, M., Izzo, L., Zeng, X., Trefely, S., Fernandez, S., Carrer, A., et al. (2020) · Nature

Diet, Metabolism, and DiseaseLipid metabolism and biosynthesis

Cited by 553

NAD+ metabolism governs the proinflammatory senescence-associated secretome

Nacarelli, T., Lau, L., Fukumoto, T., Zundell, J., Fatkhutdinov, N., Wu, S., Aird, K. M., Iwasaki, O., Kossenkov, A. V., Schultz, D., et al. (2019) · Nature Cell Biology

Sirtuins and Resveratrol in MedicineTelomeres, Telomerase, and Senescence

Cited by 402

The metabolic fate of acetate in cancer

Schug, Z. T., Vande Voorde, J., & Gottlieb, E. (2016) · Nature reviews. Cancer

Cancer, Lipids, and MetabolismCancer, Hypoxia, and Metabolism

Cited by 331

Cancer metabolism at a glance

Vazquez, A., Kamphorst, J. J., Markert, E. K., Schug, Z. T., Tardito, S., & Gottlieb, E. (2016) · Journal of Cell Science

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 225

Glycine decarboxylase maintains mitochondrial protein lipoylation to support tumor growth

Mukha, D., Fokra, M., Feldman, A., Sarvin, B., Sarvin, N., Nevo-Dinur, K., Besser, E., Hallo, E., Aizenshtein, E., Schug, Z. T., et al. (2022) · Cell Metabolism

Cancer, Hypoxia, and MetabolismBiochemical Acid Research Studies

Cited by 69