Newsholme, Philip

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

Masters, S. L., Dunne, A., Subramanian, S. L., Hull, R. L., Tannahill, G. M., Sharp, F. A., Becker, C., Franchi, L., Yoshihara, E., Chen, Z., et al. (2010) · Nature Immunology

Inflammasome and immune disordersPancreatic function and diabetes

Cited by 1,330

Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation

Cruzat, V., Macedo Rogero, M., Noel Keane, K., Curi, R., & Newsholme, P. (2018) · Nutrients

Clinical Nutrition and GastroenterologyAmino Acid Enzymes and Metabolism

Cited by 1,261

Glutamine: Metabolism and Immune Function, Supplementation and Clinical Translation

Cruzat, V., Macedo Rogero, M., Noel Keane, K., Curi, R., & Newsholme, P. (2018) · Nutrients

Clinical Nutrition and GastroenterologyAmino Acid Enzymes and Metabolism

Cited by 1,261

Molecular mechanisms of ROS production and oxidative stress in diabetes

Newsholme, P., Cruzat, V. F., Keane, K. N., Carlessi, R., & de Bittencourt, P. I. H. (2016) · Biochemical Journal

Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress

Cited by 878

Diabetes associated cell stress and dysfunction: role of mitochondrial and non-mitochondrial ROS production and activity.

Newsholme, P., Haber, E. P., Hirabara, S. M., Rebelato, E. L. O., Procopio, J., Morgan, D., Oliveira‐Emilio, H. C., Carpinelli, A. R., & Curi, R. (2007) · The Journal of Physiology

Redox biology and oxidative stressNitric Oxide and Endothelin Effects

Cited by 684

Pleiotropic Effects of GLP-1 and Analogs on Cell Signaling, Metabolism, and Function

Rowlands, J., Heng, J., Newsholme, P., & Carlessi, R. (2018) · Frontiers in Endocrinology

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 302

Effect of low-to-moderate amounts of dietary fish oil on neutrophil lipid composition and function

Healy, D. A., Wallace, F. A., Miles, E. A., Calder, P. C., & Newsholme, P. (2000) · Lipids

Fatty Acid Research and HealthEdible Oils Quality and Analysis

Cited by 227

Epigenetic effects of metformin: from molecular mechanisms to clinical implications

Bridgeman, S. C., Ellison, G. C., Melton, P. E., Newsholme, P., & Mamotte, C. D. S. (2018) · Diabetes, Obesity and Metabolism

Metabolism, Diabetes, and CancerEpigenetics and DNA Methylation

Cited by 190

Mechanisms of vitamin D action in skeletal muscle

Montenegro, K. R., Cruzat, V., Carlessi, R., & Newsholme, P. (2019) · Nutrition Research Reviews

Vitamin D Research StudiesMuscle Physiology and Disorders

Cited by 147

Glucose metabolism in lymphoid and inflammatory cells and tissues

Calder, P. C., Dimitriadis, G., & Newsholme, P. (2007) · Current Opinion in Clinical Nutrition and Metabolic Care

Hyperglycemia and glycemic control in critically ill and hospitalized patientsMetabolism, Diabetes, and Cancer

Cited by 143

Detrimental actions of metabolic syndrome risk factor, homocysteine, on pancreatic β-cell glucose metabolism and insulin secretion

Patterson, S., Flatt, P. R., Brennan, L., Newsholme, P., & McClenaghan, N. H. (2006) · Journal of Endocrinology

Pancreatic function and diabetesFolate and B Vitamins Research

Cited by 63