Rosen, Evan D.

Adipocyte differentiation from the inside out

Rosen, E. D., & MacDougald, O. A. (2006) · Nature Reviews Molecular Cell Biology

Adipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 2,607

Reactive oxygen species have a causal role in multiple forms of insulin resistance

Houstis, N., Rosen, E. D., & Lander, E. S. (2006) · Nature

Redox biology and oxidative stressMetabolism, Diabetes, and Cancer

Cited by 2,525

What we talk about when we talk about fat

Rosen, E. D., & Spiegelman, B. M. (2014) · Cell

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 2,373

Adipocytes as regulators of energy balance and glucose homeostasis

Rosen, E. D., & Spiegelman, B. M. (2006) · Nature

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 2,170

Charting a dynamic DNA methylation landscape of the human genome

Ziller, M. J., Gu, H., Müller, F., Donaghey, J., Tsai, L. T.-Y., Kohlbacher, O., De Jager, P. L., Rosen, E. D., Bennett, D. A., Bernstein, B. E., et al. (2013) · Nature

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 1,357

A single-cell atlas of human and mouse white adipose tissue

Emont, M. P., Jacobs, C., Essene, A. L., Pant, D., Tenen, D., Colleluori, G., Di Vincenzo, A., Jørgensen, A. M., Dashti, H., Stefek, A., et al. (2022) · Nature

Adipose Tissue and MetabolismSingle-cell and spatial transcriptomics

Cited by 840

A molecular census of arcuate hypothalamus and median eminence cell types

Campbell, J. N., Macosko, E. Z., Fenselau, H., Pers, T. H., Lyubetskaya, A., Tenen, D., Goldman, M., Verstegen, A. M. J., Resch, J. M., McCarroll, S. A., et al. (2017) · Nature Neuroscience

Regulation of Appetite and ObesitySingle-cell and spatial transcriptomics

Cited by 817

Muscle-specific PPARγ-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones

Norris, A. W., Chen, L., Fisher, S. J., Szanto, I., Ristow, M., Jozsi, A. C., Hirshman, M. F., Rosen, E. D., Goodyear, L. J., Gonzalez, F. J., et al. (2003) · Journal of Clinical Investigation

Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism

Cited by 417

Lessons on Conditional Gene Targeting in Mouse Adipose Tissue

Lee, K. Y., Russell, S. J., Ussar, S., Boucher, J., Vernochet, C., Mori, M. A., Smyth, G., Rourk, M., Cederquist, C., Rosen, E. D., et al. (2013) · Diabetes

Adipose Tissue and MetabolismCRISPR and Genetic Engineering

Cited by 328

Prospective functional classification of all possible missense variants in PPARG

UK Monogenic Diabetes Consortium, Majithia, A. R., Myocardial Infarction Genetics Consortium, UK Congenital Lipodystrophy Consortium, Tsuda, B., Agostini, M., Gnanapradeepan, K., Rice, R., Peloso, G., Patel, K. A., et al. (2016) · Nature Genetics

Genomics and Rare DiseasesPeroxisome Proliferator-Activated Receptors

Cited by 227

Adipocytes fail to maintain cellular identity during obesity due to reduced PPARγ activity and elevated TGFβ-SMAD signaling

Roh, H. C., Kumari, M., Taleb, S., Tenen, D., Jacobs, C., Lyubetskaya, A., Tsai, L. T.-Y., & Rosen, E. D. (2020) · Molecular Metabolism

Peroxisome Proliferator-Activated ReceptorsAdipokines, Inflammation, and Metabolic Diseases

Cited by 62

Aging impairs cold-induced beige adipogenesis and adipocyte metabolic reprogramming

Holman, C. D., Sakers, A. P., Calhoun, R. P., Cheng, L., Fein, E. C., Jacobs, C., Tsai, L., Rosen, E. D., & Seale, P. (2024) · eLife

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 8