Shenk, Thomas

Second-strand synthesis is a rate-limiting step for efficient transduction by recombinant adeno-associated virus vectors

Ferrari, F. K., Samulski, T., Shenk, T., & Samulski, R. J. (1996) · Journal of Virology

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 761

Nucleo‐cytoplasmic shuttling of the hdm2 oncoprotein regulates the levels of the p53 protein via a pathway used by the human immunodeficiency virus rev protein

Roth, J., Dobbelstein, M., Freedman, D. A., Shenk, T., & Levine, A. J. (1998) · The EMBO Journal

Cancer-related Molecular PathwaysNuclear Structure and Function

Cited by 610

Identification of Proteins in Human Cytomegalovirus (HCMV) Particles: the HCMV Proteome

Varnum, S. M., Streblow, D. N., Monroe, M. E., Smith, P., Auberry, K. J., Paša-Tolić, L., Wang, D., Camp, D. G., Rodland, K., Wiley, S., et al. (2004) · Journal of Virology

Cytomegalovirus and herpesvirus researchAdvanced Proteomics Techniques and Applications

Cited by 598

Sirtuin 4 is a lipoamidase regulating pyruvate dehydrogenase complex activity

Mathias, R. A., Greco, T. M., Oberstein, A., Budayeva, H. G., Chakrabarti, R., Rowland, E. A., Kang, Y., Shenk, T., & Cristea, I. M. (2014) · Cell

Sirtuins and Resveratrol in MedicineBiochemical Acid Research Studies

Cited by 430

A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin gene.

Logan, J., Falck-Pedersen, E., Darnell, J. E., & Shenk, T. (1987) · Proceedings of the National Academy of Sciences

RNA Research and SplicingGenomics and Chromatin Dynamics

Cited by 261

Adenovirus tripartite leader sequence enhances translation of mRNAs late after infection

Logan, J., & Shenk, T. (1984) · Proceedings of the National Academy of Sciences

RNA and protein synthesis mechanismsVirus-based gene therapy research

Cited by 198

Human Cytomegalovirus Protein UL38 Inhibits Host Cell Stress Responses by Antagonizing the Tuberous Sclerosis Protein Complex

Moorman, N. J., Cristea, I. M., Terhune, S. S., Rout, M. P., Chait, B. T., & Shenk, T. (2008) · Cell Host & Microbe

Cytomegalovirus and herpesvirus researchViral-associated cancers and disorders

Cited by 194

Human Cytomegalovirus pUL83 Stimulates Activity of the Viral Immediate-Early Promoter through Its Interaction with the Cellular IFI16 Protein

Cristea, I. M., Moorman, N. J., Terhune, S. S., Cuevas, C. D., O'Keefe, E. S., Rout, M. P., Chait, B. T., & Shenk, T. (2010) · Journal of Virology

Cytomegalovirus and herpesvirus researchinterferon and immune responses

Cited by 155

Saturated Very Long Chain Fatty Acids Are Required for the Production of Infectious Human Cytomegalovirus Progeny

Koyuncu, E., Purdy, J. G., Rabinowitz, J. D., & Shenk, T. (2013) · PLoS Pathogens

Cytomegalovirus and herpesvirus researchCancer, Lipids, and Metabolism

Cited by 114

Fatty Acid Elongase 7 Catalyzes Lipidome Remodeling Essential for Human Cytomegalovirus Replication

Purdy, J. G., Shenk, T., & Rabinowitz, J. D. (2015) · Cell Reports

Cytomegalovirus and herpesvirus researchCancer, Lipids, and Metabolism

Cited by 103

A Targeted Spatial-Temporal Proteomics Approach Implicates Multiple Cellular Trafficking Pathways in Human Cytomegalovirus Virion Maturation

Moorman, N. J., Sharon-Friling, R., Shenk, T., & Cristea, I. M. (2010) · Molecular & Cellular Proteomics

Cytomegalovirus and herpesvirus researchHerpesvirus Infections and Treatments

Cited by 97

Increased Expression of LDL Receptor-Related Protein 1 during Human Cytomegalovirus Infection Reduces Virion Cholesterol and Infectivity

Gudleski-O'Regan, N., Greco, T. M., Cristea, I. M., & Shenk, T. (2012) · Cell Host & Microbe

Cytomegalovirus and herpesvirus researchHerpesvirus Infections and Treatments

Cited by 84

Human Cytomegalovirus UL29/28 Protein Interacts with Components of the NuRD Complex Which Promote Accumulation of Immediate-Early RNA

Terhune, S. S., Moorman, N. J., Cristea, I. M., Savaryn, J. P., Cuevas-Bennett, C., Rout, M. P., Chait, B. T., & Shenk, T. (2010) · PLoS Pathogens

Cytomegalovirus and herpesvirus researchGenomics and Chromatin Dynamics

Cited by 70

HSATII RNA is induced via a noncanonical ATM-regulated DNA damage response pathway and promotes tumor cell proliferation and movement

Nogalski, M. T., & Shenk, T. (2020) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 25