Simons, Kai

Functional rafts in cell membranes

Simons, K., & Ikonen, E. (1997) · Nature

Lipid Membrane Structure and BehaviorCaveolin-1 and cellular processes

Cited by 9,757

Lipid rafts as a membrane-organizing principle

Lingwood, D., & Simons, K. (2010) · Science

Lipid Membrane Structure and BehaviorCaveolin-1 and cellular processes

Cited by 4,417

Alzheimer’s disease β-amyloid peptides are released in association with exosomes

Rajendran, L., Honsho, M., Zahn, T. R., Keller, P., Geiger, K. D., Verkade, P., & Simons, K. (2006) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsCellular transport and secretion

Cited by 1,343

Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

Chavrier, P., Parton, R. G., Hauri, H. P., Simons, K., & Zerial, M. (1990) · Cell

Cellular transport and secretionCalcium signaling and nucleotide metabolism

Cited by 1,166

Modulation of Myelopoiesis Progenitors Is an Integral Component of Trained Immunity

Mitroulis, I., Ruppova, K., Wang, B., Chen, L.-S., Grzybek, M., Grinenko, T., Eugster, A., Troullinaki, M., Palladini, A., Kourtzelis, I., et al. (2018) · Cell

Immune responses and vaccinationsImmune Response and Inflammation

Cited by 1,100

The subcellular organization of Madin-Darby canine kidney cells during the formation of a polarized epithelium

Bacallao, R., Antony, C., Dotti, C., Karsenti, E., Stelzer, E. H., & Simons, K. (1989) · The Journal of cell biology

Barrier Structure and Function StudiesCellular Mechanics and Interactions

Cited by 513

Regulation of human EGF receptor by lipids

Coskun, Ü., Grzybek, M., Drechsel, D., & Simons, K. (2011) · Proceedings of the National Academy of Sciences

Lipid Membrane Structure and BehaviorHER2/EGFR in Cancer Research

Cited by 316

Sorting of an apical plasma membrane glycoprotein occurs before it reaches the cell surface in cultured epithelial cells.

Matlin, K. S., & Simons, K. (1984) · The Journal of cell biology

Cellular transport and secretionIon Transport and Channel Regulation

Cited by 253

Lysosomal fusion and SNARE function are impaired by cholesterol accumulation in lysosomal storage disorders

Fraldi, A., Annunziata, F., Lombardi, A., Kaiser, H., Medina, D. L., Spampanato, C., Fedele, A. O., Polishchuk, R., Sorrentino, N. C., Simons, K., et al. (2010) · The EMBO Journal

Lysosomal Storage Disorders ResearchCellular transport and secretion

Cited by 225

Functional convergence of hopanoids and sterols in membrane ordering

Sáenz, J. P., Sezgin, E., Schwille, P., & Simons, K. (2012) · Proceedings of the National Academy of Sciences

Lipid Membrane Structure and BehaviorSteroid Chemistry and Biochemistry

Cited by 181

pH-induced microtubule-dependent redistribution of late endosomes in neuronal and epithelial cells

Parton, R. G., Dotti, C. G., Bacallao, R., Kurtz, I., Simons, K., & Prydz, K. (1991) · The Journal of cell biology

Cellular transport and secretionMicrotubule and mitosis dynamics

Cited by 115

Lipidomics in Major Depressive Disorder

Walther, A., Cannistraci, C. V., Simons, K., Durán, C., Gerl, M. J., Wehrli, S., & Kirschbaum, C. (2018) · Frontiers in Psychiatry

Metabolomics and Mass Spectrometry StudiesTreatment of Major Depression

Cited by 77

Heritability and responses to high fat diet of plasma lipidomics in a twin study

Frahnow, T., Osterhoff, M. A., Hornemann, S., Kruse, M., Surma, M. A., Klose, C., Simons, K., & Pfeiffer, A. F. H. (2017) · Scientific Reports

Metabolomics and Mass Spectrometry StudiesNutrition, Genetics, and Disease

Cited by 46