Lipidomics in Major Depressive Disorder

Deep learning

LeCun, Y., Bengio, Y., & Hinton, G. (2015) · Nature · doi:10.1038/nature14539 · Cited by 84,126 · see citing works

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement

Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823 · see citing works

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

Moher, D., Liberati, A., Tetzlaff, J., & Altman, D. G. (2009) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2009.06.005 · Cited by 19,575 · see citing works

Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Vos, T., Abajobir, A. A., Abate, K. H., Abbafati, C., Abbas, K. M., Abd-Allah, F., Abdulkader, R. S., Abdulle, A. M., Abebo, T. A., Abera, S. F., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)32154-2 · Cited by 13,220 · see citing works

Membrane lipids: where they are and how they behave

van Meer, G., Voelker, D. R., & Feigenson, G. W. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2330 · Cited by 7,157 · see citing works

The relationship between Precision-Recall and ROC curves

Davis, J., & Goadrich, M. (2006) · Proceedings of the 23rd international conference on Machine learning - ICML '06 · doi:10.1145/1143844.1143874 · Cited by 6,559 · see citing works

Principles of bioactive lipid signalling: lessons from sphingolipids

Hannun, Y. A., & Obeid, L. M. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2329 · Cited by 3,331 · see citing works

Resting-state connectivity biomarkers define neurophysiological subtypes of depression

Drysdale, A. T., Grosenick, L., Downar, J., Dunlop, K., Mansouri, F., Meng, Y., Fetcho, R. N., Zebley, B., Oathes, D. J., Etkin, A., et al. (2017) · Nature Medicine · doi:10.1038/nm.4246 · Cited by 2,170 · see citing works

LMSD: LIPID MAPS structure database

Sud, M., Fahy, E., Cotter, D., Brown, A., Dennis, E. A., Glass, C. K., Merrill, A. H., Murphy, R. C., Raetz, C. R. H., Russell, D. W., et al. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl838 · Cited by 1,388 · see citing works

Revitalizing membrane rafts: new tools and insights

Simons, K., & Gerl, M. J. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2977 · Cited by 1,234 · see citing works

DSM-5 field trials in the United States and Canada, part II: test-retest reliability of selected categorical diagnoses

Regier, D. A., Narrow, W. E., Clarke, D. E., Kraemer, H. C., Kuramoto, S. J., Kuhl, E. A., & Kupfer, D. J. (2013) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2012.12070999 · Cited by 1,163 · see citing works

Phospholipase A2 structure/function, mechanism, and signaling

Burke, J. E., & Dennis, E. A. (2009) · Journal of Lipid Research · doi:10.1194/jlr.r800033-jlr200 · Cited by 933 · see citing works

The Costs of Depression

Kessler, R. C. (2012) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2011.11.005 · Cited by 871 · see citing works

Lipidomics: coming to grips with lipid diversity

Shevchenko, A., & Simons, K. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2934 · Cited by 828 · see citing works

Developing constructs for psychopathology research: Research domain criteria

Sanislow, C. A., Pine, D. S., Quinn, K. J., Kozak, M. J., Garvey, M. A., Heinssen, R. K., Wang, P. S.-E., & Cuthbert, B. N. (2010) · Journal of Abnormal Psychology · doi:10.1037/a0020909 · Cited by 793 · see citing works

Identification of 15 genetic loci associated with risk of major depression in individuals of European descent

Hyde, C. L., Nagle, M. W., Tian, C., Chen, X., Paciga, S. A., Wendland, J. R., Tung, J. Y., Hinds, D. A., Perlis, R. H., & Winslow, A. R. (2016) · Nature Genetics · doi:10.1038/ng.3623 · Cited by 784 · see citing works

The Impact of Comorbidity of Mental and Physical Conditions on Role Disability in the US Adult Household Population

Merikangas, K. R., Ames, M., Cui, L., Stang, P. E., Ustun, T. B., Von Korff, M., & Kessler, R. C. (2007) · Archives of General Psychiatry · doi:10.1001/archpsyc.64.10.1180 · Cited by 464 · see citing works

The Human Plasma Lipidome

Quehenberger, O., & Dennis, E. A. (2011) · New England Journal of Medicine · doi:10.1056/nejmra1104901 · Cited by 462 · see citing works

Treatment resistant depression: A multi-scale, systems biology approach

Akil, H., Gordon, J. A., Hen, R., Javitch, J. A., Mayberg, H. S., McEwen, B. S., Meaney, M. J., & Nestler, E. J. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.08.019 · Cited by 443 · see citing works

Lipid rafts in neuronal signaling and function.

Tsui-Pierchala, B. A., Encinas, M., Milbrandt, J., & Johnson, E. M. (2002) · Trends in Neurosciences · doi:10.1016/s0166-2236(02)02215-4 · Cited by 420 · see citing works

Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950–Metabolites in Frozen Human Plasma

Bowden, J. A., Heckert, N. A., Ulmer, C. Z., Jones, C. M., Koelmel, J. P., Abdullah, L. I., Ahonen, L. L., Alnouti, Y., Armando, A. M., Asara, J. M., et al. (2017) · Journal of Lipid Research · doi:10.1194/jlr.m079012 · Cited by 405 · see citing works

Acid sphingomyelinase–ceramide system mediates effects of antidepressant drugs

Gulbins, E., Palmada, M., Reichel, M., Lüth, A., Böhmer, C., Amato, D., Müller, C. P., Tischbirek, C. H., Groemer, T. W., Tabatabai, G., et al. (2013) · Nature Medicine · doi:10.1038/nm.3214 · Cited by 384 · see citing works

Why are depressed patients inflamed? A reflection on 20 years of research on depression, glucocorticoid resistance and inflammation

Pariante, C. M. (2017) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2017.04.001 · Cited by 382 · cited 2× · see citing works

GFRα-Mediated Localization of RET to Lipid Rafts Is Required for Effective Downstream Signaling, Differentiation, and Neuronal Survival

Tansey, M. G., Baloh, R. H., Milbrandt, J., & Johnson, E. M. (2000) · Neuron · doi:10.1016/s0896-6273(00)81064-8 · Cited by 307 · see citing works

An automated shotgun lipidomics platform for high throughput, comprehensive, and quantitative analysis of blood plasma intact lipids

Surma, M. A., Herzog, R., Vasilj, A., Klose, C. D., Christinat, N., Morin‐Rivron, D., Simons, K., Masoodi, M., & Sampaio, J. L. (2015) · European Journal of Lipid Science and Technology · doi:10.1002/ejlt.201500145 · Cited by 285 · see citing works

Brain microglia in psychiatric disorders

Mondelli, V., Vernon, A. C., Turkheimer, F., Dazzan, P., & Pariante, C. M. (2017) · The Lancet Psychiatry · doi:10.1016/s2215-0366(17)30101-3 · Cited by 262 · see citing works

Trans-Omics: How To Reconstruct Biochemical Networks Across Multiple ‘Omic’ Layers

Yugi, K., Kubota, H., Hatano, A., & Kuroda, S. (2016) · Trends in Biotechnology · doi:10.1016/j.tibtech.2015.12.013 · Cited by 258 · see citing works

The impact of chronic stress on the rat brain lipidome

Oliveira, T. G., Chan, R., Bravo, F. V., Miranda, A. M., Caridade-Silva, R., Zhou, B., Marques, F., Pinto, V., Cerqueira, J., Paolo, G. D., et al. (2015) · Molecular Psychiatry · doi:10.1038/mp.2015.14 · Cited by 219 · see citing works

DSM-5 field trials in the United States and Canada, part I: study design, sampling strategy, implementation, and analytic approaches

Clarke, D. E., Narrow, W. E., Regier, D. A., Kuramoto, S. J., Kupfer, D. J., Kuhl, E. A., Greiner, L., & Kraemer, H. C. (2013) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2012.12070998 · Cited by 201 · see citing works

Discovery and Validation of Plasma Biomarkers for Major Depressive Disorder Classification Based on Liquid Chromatography–Mass Spectrometry

Liu, X., Zheng, P., Zhao, X., Zhang, Y., Hu, C., Li, J., Zhao, J., Zhou, J., Xie, P., & Xu, G. (2015) · Journal of Proteome Research · doi:10.1021/acs.jproteome.5b00144 · Cited by 193 · see citing works

Efficacy of omega-3 highly unsaturated fatty acids in the treatment of depression

Hallahan, B. P., Ryan, T. J., Hibbeln, J. R., Murray, I. T., Glynn, S., Ramsden, C. E., SanGiovanni, J. P., & Davis, J. M. (2016) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.114.160242 · Cited by 192 · see citing works

Lipids in Psychiatric Disorders and Preventive Medicine

Schneider, M., Levant, B., Reichel, M., Gulbins, E., Kornhuber, J., & Müller, C. P. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.06.002 · Cited by 175 · see citing works

Plasma Phosphatidylcholine and Sphingomyelin Concentrations Are Associated with Depression and Anxiety Symptoms in a Dutch Family-Based Lipidomics Study

Demirkan, A., Isaacs, A., Ugocsai, P., Liebisch, G., Struchalin, M., Rudan, I., Wilson, J. F., Pramstaller, P. P., Gyllensten, U., Campbell, H., et al. (2013) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2012.11.001 · Cited by 163 · see citing works

The SwissLipids knowledgebase for lipid biology

Aimo, L., Liechti, R., Hyka‐Nouspikel, N., Niknejad, A., Gleizes, A., Götz, L., Kuznetsov, D. A., David, F. P. A., van der Goot, F. G., Riezman, H., et al. (2015) · Bioinformatics · doi:10.1093/bioinformatics/btv285 · Cited by 157 · see citing works

Lipid changes in the aged brain: Effect on synaptic function and neuronal survival

Ledesma, M. D., Martín, M. G., & Dotti, C. G. (2011) · Progress in Lipid Research · doi:10.1016/j.plipres.2011.11.004 · Cited by 148 · see citing works

Plasma lipidomics reveals potential lipid markers of major depressive disorder

Liu, X., Li, J., Zheng, P., Zhao, X., Zhou, C., Hu, C., Hou, X., Wang, H., Xie, P., & Xu, G. (2016) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-016-9768-5 · Cited by 148 · see citing works

Regulation of the enzymes of hepatic microsomal triacylglycerol lipolysis and re-esterification by the glucocorticoid dexamethasone

Dolinsky, V. W., Douglas, D. N., Lehner, R. S., & Vance, D. E. (2004) · Biochemical Journal · doi:10.1042/bj20031320 · Cited by 128 · see citing works

The role of lipid biomarkers in major depression

Parekh, A., Smeeth, D., Milner, Y., & Thuret, S. (2017) · Healthcare · doi:10.3390/healthcare5010005 · Cited by 120 · see citing works

Functions and pathophysiological roles of phospholipase D in the brain

Klein, J. (2005) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2005.03315.x · Cited by 119 · see citing works

Neurogenetics of depression: A focus on reward processing and stress sensitivity

Bogdan, R., Nikolova, Y. S., & Pizzagalli, D. A. (2012) · Neurobiology of Disease · doi:10.1016/j.nbd.2012.05.007 · Cited by 105 · see citing works

Alterations in phospholipidomic profile in the brain of mouse model of depression induced by chronic unpredictable stress

Faria, R., Santana, M. M., Aveleira, C. A., Simões, C. S. O., Maciel, E. A., Melo, T., Santinha, D. R., Oliveira, M. M., Peixoto, F., Domingues, P. M., et al. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.04.042 · Cited by 76 · see citing works

Nonlinear dimension reduction and clustering by Minimum Curvilinearity unfold neuropathic pain and tissue embryological classes

Cannistraci, C. V., Ravasi, T., Montevecchi, F. M., Ideker, T. E., & Alessio, M. (2010) · Bioinformatics · doi:10.1093/bioinformatics/btq376 · Cited by 75 · see citing works

Conjugated linoleic acid increased C-reactive protein in human subjects

Smedman, A., Basu, S., Jovinge, S. V., Fredrikson, G. N., & Vessby, B. O. (2005) · British Journal Of Nutrition · doi:10.1079/bjn20041419 · Cited by 73 · see citing works

Tryptophan-kynurenine and lipid related metabolites as blood biomarkers for first-episode drug-naïve patients with major depressive disorder: An exploratory pilot case-control study

Kuwano, N., Kato, T. A., Setoyama, D., Sato-Kasai, M., Shimokawa, N., Hayakawa, K., Ohgidani, M., Sagata, N., Kubo, H., Kishimoto, J., et al. (2018) · Journal of Affective Disorders · doi:10.1016/j.jad.2018.01.014 · Cited by 69 · see citing works

Relationship between the hypothalamic–pituitary–adrenal-axis and fatty acid metabolism in recurrent depression

Mocking, R. J. T., Ruhé, H. G., Assies, J., Lok, A., Koeter, M. W. J., Visser, I., Bockting, C., & Schene, A. H. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2013.01.013 · Cited by 68 · see citing works

Risk factors for cardiovascular disease: renewed interest in triglycerides

Berglund, L., Sacks, F. M., & Brunzell, J. D. (2013) · Clinical Lipidology · doi:10.2217/clp.12.81 · Cited by 63 · see citing works

Enlightening discriminative network functional modules behind Principal Component Analysis separation in differential-omic science studies

Ciucci, S., Ge, Y., Durán, C., Palladini, A., Jiménez-Jiménez, V., Martínez-Sánchez, L. M., Wang, Y., Sales, S., Shevchenko, A., Poser, S., et al. (2017) · Scientific Reports · doi:10.1038/srep43946 · Cited by 52 · see citing works

Dietary linoleic acid intake and blood inflammatory markers: a systematic review and meta-analysis of randomized controlled trials

Su, H., Liu, R., Chang, M., Huang, J., & Wang, X. (2017) · Food & Function · doi:10.1039/c7fo00433h · Cited by 52 · see citing works

LIPEA: Lipid Pathway Enrichment AnalysisPreprint

Acevedo, A., Durán, C., Ciucci, S., Gerl, M. J., & Cannistraci, C. V. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/274969 · Cited by 50 · see citing works

Serum lipidomic analysis for the discovery of biomarkers for major depressive disorder in drug-free patients

Kim, E. Y., Lee, J. W., Lee, M. Y., Kim, S. H., Mok, H. J., Ha, K., Ahn, Y. M., & Kim, K. P. (2018) · Psychiatry Research · doi:10.1016/j.psychres.2018.04.029 · Cited by 50 · see citing works

Effect of Allium macrostemon on a rat model of depression studied by using plasma lipid and acylcarnitine profiles from liquid chromatography/mass spectrometry

Chen, S., Wei, C., Gao, P., Kong, H., Jia, Z., Hu, C., Dai, W., Wu, Y., & Xu, G. (2013) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2013.10.045 · Cited by 49 · see citing works

Altered soluble epoxide hydrolase-derived oxylipins in patients with seasonal major depression: An exploratory study

Hennebelle, M., Otoki, Y., Yang, J., Hammock, B. D., LEVITT, A. J., Taha, A. Y., & Swardfager, W. (2017) · Psychiatry Research · doi:10.1016/j.psychres.2017.02.056 · Cited by 47 · see citing works

Metabolomic biosignature differentiates melancholic depressive patients from healthy controls

Liu, Y., Yieh, L., Yang, T., Drinkenburg, W. H. I. M., Peeters, P. J., Steckler, T., Narayan, V. A., Wittenberg, G. M., & Ye, J. (2016) · BMC Genomics · doi:10.1186/s12864-016-2953-2 · Cited by 45 · see citing works

Fatty acid metabolism and its longitudinal relationship with the hypothalamic–pituitary–adrenal axis in major depression: Associations with prospective antidepressant response

Mocking, R. J. T., Verburg, H. F., Westerink, A. M., Assies, J., Vaz, F. M., Koeter, M. W. J., Ruhé, H. G., & Schene, A. H. (2015) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2015.04.027 · Cited by 44 · see citing works

Lipidomic analyses of the mouse brain after antidepressant treatment: evidence for endogenous release of long-chain fatty acids?

Lee, L. H.-W., Shui, G., Farooqui, A. A., Wenk, M. R., Tan, C. H., & Ong, W. (2009) · The International Journal of Neuropsychopharmacology · doi:10.1017/s146114570900995x · Cited by 43 · see citing works

The lipidome in major depressive disorder: Shared genetic influence for ether-phosphatidylcholines, a plasma-based phenotype related to inflammation, and disease risk

Knowles, E. E. M., Huynh, K., Meikle, P. J., Göring, H. H. H., Olvera, R. L., Mathias, S. R., Duggirala, R., Almasy, L. A., Blangero, J., Curran, J. E., et al. (2017) · European Psychiatry · doi:10.1016/j.eurpsy.2017.02.479 · Cited by 43 · see citing works

Imaging biomarkers and biotypes for depression

Wager, T. D., & Woo, C.-W. (2017) · Nature Medicine · doi:10.1038/nm.4264 · Cited by 39 · see citing works

Hyperphospholipasemia A2 in human volunteers challenged with intravenous endotoxin

Pruzanski, W., Wilmore, D. W., Suffredini, A. F., Martich, G. D., Hoffman, A. G. D., Browning, J. L., Stefanski, E., Sternby, B., & Vadas, P. (1992) · Inflammation · doi:10.1007/bf00918980 · Cited by 38 · see citing works

Brain lipoprotein lipase as a regulator of energy balance

Cruciani‐Guglielmacci, C., & Magnan, C. (2017) · Biochimie · doi:10.1016/j.biochi.2017.07.012 · Cited by 35 · see citing works

Biological Profiling of Prospective Antidepressant Response in Major Depressive Disorder: Associations with (Neuro)Inflammation, Fatty Acid Metabolism, and Amygdala-Reactivity

Mocking, R. J. T., Nap, T. S., Westerink, A. M., Assies, J., Vaz, F. M., Koeter, M. W. J., Ruhé, H. G., & Schene, A. H. (2017) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2017.02.019 · Cited by 34 · see citing works

Lipidomic profiling of tryptophan hydroxylase 2 knockout mice reveals novel lipid biomarkers associated with serotonin deficiency

Weng, R., Shen, S., Burton, C., Yang, L., Nie, H., Tian, Y., Bai, Y., & Liu, H. (2016) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-015-9256-3 · Cited by 31 · see citing works

The sphingomyelin–ceramide pathway participates in cytokine regulation of C-reactive protein and serum amyloid A, but not α-fibrinogen

Lozanski, G., Berthier, F., & Kushner, I. (1997) · Biochemical Journal · doi:10.1042/bj3280271 · Cited by 25 · see citing works

Advancing Clinical Improvements for Patients Using the Theory-Driven and Data-Driven Branches of Computational Psychiatry

Huys, Q. J. M. (2018) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2017.4246 · Cited by 24 · see citing works

How Can Omic Science be Improved?

Simons, K. (2018) · PROTEOMICS · doi:10.1002/pmic.201800039 · Cited by 23 · see citing works

Role of prefrontal cortical calcium independent phospholipase A2 in antidepressant-like effect of maprotiline

Lee, L. H.-W., Tan, C. H., Shui, G., Wenk, M. R., & Ong, W. (2011) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145711001234 · Cited by 17 · see citing works

Novel Phospholipid Signature of Depressive Symptoms in Patients with Coronary Artery Disease

Chan, P., Suridjan, I., Mohammad, D., Herrmann, N., Mazereeuw, G., Hillyer, L. M., Ma, D. W. L., Oh, P. I., & Lanctôt, K. L. (2018) · Journal of the American Heart Association · doi:10.1161/jaha.117.008278 · Cited by 15 · see citing works

Neglected diseases see few new drugs despite upped investment

Willyard, C. (2013) · Nature Medicine · doi:10.1038/nm0113-2 · Cited by 11 · see citing works

Dexamethasone enhances phospholipase D activity in M-1 cells

Kim, W.-J., Lee, M.-J., Park, M.-A., Jung, J.-S., Uhlinger, D. J., & Kwak, J. (2000) · Experimental & Molecular Medicine · doi:10.1038/emm.2000.28 · Cited by 7 · see citing works

Aiding and Abetting Anhedonia: Impact of Inflammation on the Brain and Pharmacological Implications

Lucido, M. J., Bekhbat, M., Goldsmith, D. R., Treadway, M. T., Haroon, E., Felger, J. C., & Miller, A. H. (2021) · Pharmacological Reviews · doi:10.1124/pharmrev.120.000043 · Cited by 130 · see citing works

Is depression the missing link between inflammatory mediators and cancer?

Polityńska, B., Pokorska, O., Wojtukiewicz, A. M., Sawicka, M., Mysliwiec, M., Honn, K. V., Tucker, S. C., & Wojtukiewicz, M. Z. (2022) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2022.108293 · Cited by 80 · see citing works

Microglial Inflammatory-Metabolic Pathways and Their Potential Therapeutic Implication in Major Depressive Disorder

Rahimian, R., Belliveau, C., Chen, R., & Mechawar, N. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.871997 · Cited by 73 · see citing works

Identification of Lipid Heterogeneity and Diversity in the Developing Human Brain

Bhaduri, A., Neumann, E. K., Kriegstein, A. R., & Sweedler, J. V. (2021) · JACS Au · doi:10.1021/jacsau.1c00393 · Cited by 55 · see citing works

Brain Lipids and Lipid Droplet Dysregulation in Alzheimer’s Disease and Neuropsychiatric Disorders

Zhao, X., Zhang, S., Sanders, A. R., & Duan, J. (2023) · Complex Psychiatry · doi:10.1159/000535131 · Cited by 54 · see citing works

Dietary linoleic acid intake and blood inflammatory markers: a systematic review and meta-analysis of randomized controlled trials

Su, H., Liu, R., Chang, M., Huang, J., & Wang, X. (2017) · Food & Function · doi:10.1039/c7fo00433h · Cited by 52 · see citing works

Adaptation of Lipid Profiling in Depression Disease and Treatment: A Critical Review

Pinto, B., Conde, T., Domingues, I., & Domingues, M. R. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23042032 · Cited by 51 · see citing works

Statins in Depression: An Evidence-Based Overview of Mechanisms and Clinical Studies

Giorgi, R. D., Pesci, N. R., Quinton, A. M. G., Crescenzo, F. D., Cowen, P. J., & Harmer, C. J. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.702617 · Cited by 49 · see citing works

Depressive disorders are associated with increased peripheral blood cell deformability: a cross-sectional case-control study (Mood-Morph)

Walther, A., Mackens-Kiani, A., Eder, J., Herbig, M., Herold, C., Kirschbaum, C., Guck, J. R., Wittwer, L. D., Beesdo‐Baum, K., & Kräter, M. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-01911-3 · Cited by 42 · see citing works

Metabolic features of recurrent major depressive disorder in remission, and the risk of future recurrence

Mocking, R. J. T., Naviaux, J. C., Li, K., Wang, L., Monk, J. M., Bright, A. T., Figueroa, C. A., Schene, A. H., Ruhé, H. G., Assies, J., et al. (2021) · Translational Psychiatry · doi:10.1038/s41398-020-01182-w · Cited by 40 · see citing works

The association between adolescent depression and dyslipidemia

Khalfan, A. F., Campisi, S. C., Lo, R. F., McCrindle, B. W., & Korczak, D. J. (2023) · Journal of Affective Disorders · doi:10.1016/j.jad.2023.06.017 · Cited by 37 · see citing works

Lipids in Psychiatric Disorders: Functional and Potential Diagnostic Role as Blood Biomarkers

Zorkina, Y., Ushakova, V., Ochneva, A., Tsurina, A., Abramova, O., Savenkova, V., Goncharova, A., Alekseenko, I., Morozova, I., Riabinina, D., et al. (2024) · Metabolites · doi:10.3390/metabo14020080 · Cited by 36 · see citing works

Plasma lipidomic profile of depressive symptoms: a longitudinal study in a large sample of community-dwelling American Indians in the strong heart study

Miao, G., Deen, J. F., Struzeski, J. B., Chen, M., Zhang, Y., Cole, S. A., Fretts, A. M., Lee, E. T., Howard, B. V., Fiehn, O., et al. (2023) · Molecular Psychiatry · doi:10.1038/s41380-023-01948-w · Cited by 36 · see citing works

Biological Profiling of Prospective Antidepressant Response in Major Depressive Disorder: Associations with (Neuro)Inflammation, Fatty Acid Metabolism, and Amygdala-Reactivity

Mocking, R. J. T., Nap, T. S., Westerink, A. M., Assies, J., Vaz, F. M., Koeter, M. W. J., Ruhé, H. G., & Schene, A. H. (2017) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2017.02.019 · Cited by 34 · see citing works

Comparative metabolomic analysis in plasma and cerebrospinal fluid of humans and in plasma and brain of mice following antidepressant-dose ketamine administration

Moaddel, R., Zanos, P., Farmer, C., Kadriu, B., Morris, P. J., Lovett, J., Acevedo-Diaz, E. E., Cavanaugh, G. W., Yuan, P., Yavi, M., et al. (2022) · Translational Psychiatry · doi:10.1038/s41398-022-01941-x · Cited by 31 · see citing works

Lipidomics and genomics in mental health: insights into major depressive disorder, bipolar disorder, schizophrenia, and obsessive-compulsive disorder

Modesti, M. N., Arena, J. F., CASALE, A. D., Gentile, G., Borro, M., Parmigiani, G., Simmaco, M., Guariglia, C., & Ferracuti, S. (2025) · Lipids in Health and Disease · doi:10.1186/s12944-025-02512-x · Cited by 28 · see citing works

Antihypertensive activity of oleanolic acid is mediated via downregulation of secretory phospholipase A2 and fatty acid synthase in spontaneously hypertensive rats

Zhang, S., Liu, Y., Wang, X., Tian, Z., Qi, D., Li, Y., & Jiang, H. (2020) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2020.4744 · Cited by 27 · see citing works

The pharmacological bases for repurposing statins in depression: a review of mechanistic studies

Giorgi, R. D., Pesci, N. R., Rosso, G., Maina, G., Cowen, P. J., & Harmer, C. J. (2023) · Translational Psychiatry · doi:10.1038/s41398-023-02533-z · Cited by 29 · see citing works

Impaired hippocampal neurogenesis in vitro is modulated by dietary-related endogenous factors and associated with depression in a longitudinal ageing cohort study

Preez, A. D., Lefèvre‐Arbogast, S., González‐Domínguez, R., Houghton, V., de Lucia, C., Low, D. Y., Helmer, C., Féart, C., Delcourt, C., Proust‐Lima, C., et al. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01644-1 · Cited by 26 · see citing works

Changed cortical risk gene expression in major depression and shared changes in cortical gene expression between major depression and bipolar disorders

Scarr, E., Udawela, M., & Dean, B. (2019) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867419857808 · Cited by 24 · see citing works

Probiotic Lactobacillus plantarum 299v supplementation in patients with major depression in a double-blind, randomized, placebo-controlled trial: A metabolomics study

Godzień, J., Kałaska, B., Rudzki, L., Barbas-Bernardos, C., Swieton, J., López‐Gonzálvez, Á., Ostrowska, L., Szulc, A., Waszkiewicz, N., Ciborowski, M., et al. (2024) · Journal of Affective Disorders · doi:10.1016/j.jad.2024.09.058 · Cited by 22 · see citing works

Serotonin transporter regulation by cholesterol-independent lipid signaling

Deveau, C., Rodriguez, E., Schroering, A. G., & Yamamoto, B. K. (2020) · Biochemical Pharmacology · doi:10.1016/j.bcp.2020.114349 · Cited by 22 · see citing works

Early-life stress and dietary fatty acids impact the brain lipid/oxylipin profile into adulthood, basally and in response to LPS

Reemst, K., Broos, J. Y., Abbink, M. R., Cimetti, C., Giera, M. A., Kooij, G., & Kőrösi, A. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.967437 · Cited by 22 · see citing works

Evaluation of Serum Lysophosphatidic Acid and Lysophosphatidylcholine Levels in Major Depressive Disorder Patients

Riya, S., Sultana, S., Daria, S., Proma, M. A., Bhuiyan, M. A., Haque, M. A., & Islam, M. R. (2020) · Cureus · doi:10.7759/cureus.12388 · Cited by 20 · see citing works

Lipid Biomarker Research in Bipolar Disorder: A Scoping Review of Trends, Challenges, and Future Directions

Hiller, J. K., Jangmo, A., Tesli, M., Jaholkowski, P. P., Hoseth, E. Z., Steen, N. E., & Haram, M. (2023) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2023.07.004 · Cited by 20 · see citing works

Untargeted Plasma Metabolomic Profiling in Patients with Major Depressive Disorder Using Ultra-High Performance Liquid Chromatography Coupled with Mass Spectrometry

Homorogan, C., Nitusca, D., Enatescu, V., Schubart, P., Moraru, C., Socaciu, C., & Marian, C. (2021) · Metabolites · doi:10.3390/metabo11070466 · Cited by 19 · see citing works

Intervention of Uncaria and Its Components on Liver Lipid Metabolism in Spontaneously Hypertensive Rats

Tian, Z., Zhang, S., Wang, H., Chen, Z., Sun, M., Sun, L., Gong, L., Li, Y., & Jiang, H. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.00910 · Cited by 19 · see citing works

Determination of inflammation-related lipids in depressive rats by on-line supercritical fluid extraction-supercritical fluid chromatography-tandem mass spectrometry

Jin, W., Yang, J., Liu, D., Zhong, Q., & Zhou, T. (2021) · Journal of Pharmaceutical and Biomedical Analysis · doi:10.1016/j.jpba.2021.114210 · Cited by 19 · see citing works

Alterations in Plasma Lipidomic Profiles in Adult Patients with Schizophrenia and Major Depressive Disorder

Wang, F., Guo, L., Zhang, T., Cui, Z., Wang, J., Zhang, C., Xue, F., Zhou, C., Li, B., Tan, Q., et al. (2022) · Medicina · doi:10.3390/medicina58111509 · Cited by 18 · see citing works

Impaired lipid homeostasis and elevated lipid oxidation of erythrocyte membrane in adolescent depression

Wang, J., Hu, X., Li, Y., Li, S., Wang, T., Wang, D., Gao, Y., Wang, Q., Zhou, J., & Wan, C. (2025) · Redox Biology · doi:10.1016/j.redox.2025.103491 · Cited by 18 · see citing works

Porphyra haitanensis Polysaccharides Attenuates Blood Lipid via Gut‐Liver Axis in Diet‐Induced High‐Fat Mesocricetus auratus through Multiple Integrated Omics

Zeng, H., Chen, P., Wang, Z., Hu, X., Zhang, Y., & Zheng, B. (2022) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.202200638 · Cited by 18 · see citing works

The placental lipidome of maternal antenatal depression predicts socio-emotional problems in the offspring

Wong, G., Weir, J. M., Mishra, P., Huynh, K., Nijagal, B., Gupta, V., Broekman, B. F. P., Chong, M. F., Chan, S., Tan, K. H., et al. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01208-x · Cited by 18 · see citing works

Network science approach elucidates integrative genomic-metabolomic signature of antidepressant response and lifetime history of attempted suicide in adults with major depressive disorder

Grant, C. W., Wilton, A. R., Kaddurah-Daouk, R. F., Skime, M. K., Biernacka, J. M., Mayes, T. L., Carmody, T. J., Wang, L., Lazaridis, K. N., Weinshilboum, R. M., et al. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.984383 · Cited by 16 · see citing works

Modulatory effect of n-3 polyunsaturated fatty acids on depressive-like behaviors in rats with chronic sleep deprivation: potential involvement of melatonin receptor pathway and brain lipidome

Chang, C., Wu, H.-C., Hsieh, Y.-R., Lai, W.-D., Tung, T.-H., Huang, J.-J., Kao, W., & Huang, S. (2023) · Food & Function · doi:10.1039/d3fo01452e · Cited by 13 · see citing works

Fatty acid dysregulation in the anterior cingulate cortex of depressed suicides with a history of child abuse

Perlman, K., Chouinard‐Watkins, R., Tanti, A., Cisbani, G., Orri, M., Turecki, G., Bazinet, R. P., & Mechawar, N. (2021) · Translational Psychiatry · doi:10.1038/s41398-021-01657-4 · Cited by 12 · see citing works

The effects of atorvastatin on emotional processing, reward learning, verbal memory and inflammation in healthy volunteers: An experimental medicine study

Giorgi, R. D., Martens, M., Pesci, N. R., Cowen, P. J., & Harmer, C. J. (2021) · Journal of Psychopharmacology · doi:10.1177/02698811211060307 · Cited by 13 · see citing works

Potential Transdiagnostic Lipid Mediators of Inflammatory Activity in Individuals With Serious Mental Illness

Hylén, U., McGlinchey, A. J., Orešič, M., Bejerot, S., Humble, M. B., Särndahl, E., Hyötyläinen, T., & Eklund, D. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.778325 · Cited by 12 · see citing works

An experimental medicine study of the effects of simvastatin on emotional processing, reward learning, verbal memory, and inflammation in healthy volunteers

Giorgi, R. D., Quinton, A. M. G., Waters, S., Cowen, P. J., & Harmer, C. J. (2022) · Psychopharmacology · doi:10.1007/s00213-022-06156-y · Cited by 13 · see citing works

Human Brain Lipidomics: Investigation of Formalin Fixed Brains

Beger, A. W., Hauther, K. A., Dudzik, B., Woltjer, R. L., & Wood, P. L. (2022) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.835628 · Cited by 11 · see citing works

Identifying Depression Through Machine Learning Analysis of Omics Data: Scoping Review

Taylor, B., Hobensack, M., de Rivera, S. N., Zhao, Y., Creber, R. M., & Cato, K. (2024) · JMIR Nursing · doi:10.2196/54810 · Cited by 9 · see citing works

The impact of Dl-3-n-butylphthalide on the lipidomics of the hippocampus in a rat model of lipopolysaccharide-induced depression

Geng, C., Hao, G., Qiao, Y., Guo, Y., Chen, D., Han, W., Zhang, J., Yang, M., & Jiang, P. (2020) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2020.106464 · Cited by 9 · see citing works

Association of statin use with risk of depression and anxiety: A prospective large cohort study

Yang, Q., Yang, Z., Zeng, B., Jia, J., & Sun, F. (2024) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2024.07.015 · Cited by 8 · see citing works

Signatory metabolomics biomarkers of stress, anxiety, and depression: a proof of concept for precision health among university students: A cross-sectional study

Zaman, N. I. U., Teh, L. K., Ahmad, R., Noorizhab, M. N. F., Rofiee, M. S., James, R. J., Nor, N. M., Mohamed, M. B., Hoon, T. S., Singh, P., et al. (2023) · Precision and Future Medicine · doi:10.23838/pfm.2022.00128 · Cited by 6 · see citing works

Plasma proteomic signature of chronic psychosocial stress in mice

O'Connor, L. A., Melo, T. G., Golubeva, A. V., Donoso, F., Scaife, C., English, J. A., Nolan, Y. M., & O’Leary, O. F. (2024) · Physiology & Behavior · doi:10.1016/j.physbeh.2024.114743 · Cited by 5 · see citing works

St. John’s Wort Extract Ze 117 and Escitalopram Alter Plasma and Hippocampal Lipidome in a Rat Model of Chronic-Stress-Induced Depression

Bussmann, H., Bremer, S., Hernier, A. M., Drewe, J., Häberlein, H., Franken, S., Freytag, V., Boonen, G., & Butterweck, V. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms252312667 · Cited by 4 · see citing works

Plasma and Serum LC-MS Lipidomic Fingerprints of Bipolar Disorder and Schizophrenia

Takić, M. M., Jovanović, V. B., Marković, S., Miladinović, Z. P., Jadranin, M. B., Krstić, G., Miljević, Č., Tešević, V., & Mandić, B. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26136134 · Cited by 4 · see citing works

Serum Lipidome Change in Japanese Patients with Major Depressive Disorder: A Real-World Exploratory Study

Okamoto, N., Fujii, R., Chibaatar, E., Iino, C., Ikenouchi, A., & Yoshimura, R. (2025) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s541312 · Cited by 4 · see citing works

LC–HRMS Lipidomic Fingerprints in Serbian Cohort of Schizophrenia Patients

Marković, S., Jadranin, M. B., Miladinović, Z. P., Gavrilović, A., Avramović, N., Takić, M. M., Tasić, L., Tešević, V., & Mandić, B. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms251910266 · Cited by 4 · see citing works

Pharmaceutical Studies on Piperazine-based Compounds Targeting Serotonin Receptors and Serotonin Reuptake Transporters

Yamalı, C., Nenni, M., Sakarya, M. T., & Kaplan, H. A. (2024) · Mini-Reviews in Medicinal Chemistry · doi:10.2174/0113895575319878240612070850 · Cited by 4 · see citing works

The Crosstalk of Lipids, Brain and Diet, and Their Potential Impact on Depression Development and Prevention Strategies

Pinto, B., Domingues, I., Ferreira, H. B., Melo, T., & Domingues, M. R. (2025) · Journal of Nutrition · doi:10.1016/j.tjnut.2025.08.003 · Cited by 4 · see citing works

Blood Plasma Lipid Alterations Differentiating Psychotic and Affective Disorder Patients

Golubova, A., Stekolshchikova, E., Эмировна, Г. А., Akhmerova, I. Y., Тимербулатов, И. Ф., Zakurazhnaya, V., Riabinina, D., Reznik, A. M., Morozova, A. Y., Andreyuk, D., et al. (2025) · Biomolecules · doi:10.3390/biom15091296 · Cited by 3 · see citing works

Plasma lipidomic alterations during pathogenic SIV infection with and without antiretroviral therapy

Sivanandham, S., Sivanandham, R., Xu, C., Symmonds, J., Sette, P., He, T., Funderburg, N., Abdel‐Mohsen, M., LANDAY, A. L., Apetrei, C., et al. (2025) · Frontiers in Immunology · doi:10.3389/fimmu.2025.1475160 · Cited by 4 · see citing works

A multilayer network analysis of cardiovascular–depression comorbidity reveals symptom-specific molecular biomarkers

Li, J., Bosch, J. A., Rydin, A. O., Hourican, C., Koloi, A., Tassi, S. C., Mishra, P. P., Mishra, B., Kähönen, M., Lehtimäki, T., et al. (2025) · Psychological Medicine · doi:10.1017/s0033291725102109 · Cited by 2 · see citing works

A genome-wide investigation of depression among individuals with and without irritability

St‐Pierre, J., Jang, J., Nagy, C., Fiori, L. M., Turecki, G., Dupuis, J., Bhatnagar, S., & Orri, M. (2026) · Molecular Psychiatry · doi:10.1038/s41380-026-03548-w · Cited by 2 · see citing works

Combinatorial panel with endophenotypes from multilevel information of diffusion tensor imaging and lipid profile as predictors for depression

Liu, J., Liu, Z., Wei, Y., Zhang, Y., Womer, F. Y., Duan, J., Wei, S., Wu, F., Kong, L., Jiang, X., et al. (2022) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/00048674211031477 · Cited by 2 · see citing works

Brain-Derived Neurotrophic Factor, Kynurenine Pathway, and Lipid-Profiling Alterations as Potential Animal Welfare Indicators in Dairy Cattle

Favole, A., Testori, C., Bergagna, S., Gennero, M. S., Ingravalle, F., Costa, B., Barresi, S., Curti, P., Barberis, F., Ganio, S., et al. (2023) · Animals · doi:10.3390/ani13071167 · Cited by 2 · see citing works

Research Progress in the Correlation and Mechanism between High-Fat Diet and Depression

李, 晓. (2023) · Advances in Clinical Medicine · doi:10.12677/acm.2023.1351083 · Cited by 2 · see citing works

Untargeted lipidomic profiling and key lipoprotein analysis for mechanism clarification of therapeutic effects of Fangji Huangqi Tang on adriamycin-induced nephrotic syndrome rats

Wan, H.-T., Xie, L.-T., Xue, F.-F., Zhang, X., Li, J., Duan, Y., Zhu, H., & Liu, X. (2025) · Microchemical Journal · doi:10.1016/j.microc.2025.114675 · Cited by 2 · see citing works

Impact of Metabolomics on Depression using Data Mining Techniques

Chovancova, O., Stafurikova, A., Maceková, D., Kisková, T., Rabčan, J., & Kostolný, J. (2019) · IEEE International Conference on Intelligent Data Acquisition and Advanced Computing Systems: Technology and Applications (IDAACS) · doi:10.1109/idaacs.2019.8924245 · Cited by 2 · see citing works

Multi-omic subtypes of Alzheimer’s dementia are differentially associated with psychological traitsPreprint

Zammit, A. R., Yu, L., Poole, V. N., Arfanakis, K., Schneider, J. A., Petyuk, V., Jager, P. L. D., Kaddurah-Daouk, R. F., Iturria‐Medina, Y., & Bennett, D. A. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2025.02.21.639584 · Cited by 2 · see citing works

Lactiplantibacillus plantarum KLDS1.0344 ameliorates depressive-like behavior in CUMS mice: integrative multi-omics evidence linking gut microbiota alterations to sphingolipid and glycerophospholipid metabolic pathways

Dou, F., Li, Y., Lv, W., Sun, Y., Li, M., Li, B., Wang, Y., & Yu, W. (2026) · Food & Function · doi:10.1039/d6fo00143b · Cited by 1 · see citing works

The metabolic signature of acute psychosocial stress in humans

Tabrizi, F. F., Grönvall, H., Adbelhalim, S., Bernhardsson, J., Rosén, J., Lilja, M., Jansson, B., Sundin, Ö., Hanstock, H. G., & Åhs, F. (2026) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2026.111766 · Cited by 1 · see citing works

Whole brain lipid dyshomeostasis in depressive-like behavior young adult rats: Mapping by mass spectrometry imaging-based spatial omics

Zhao, C., Gao, C., Yang, Z., Cao, T., Luo, Q., & Zhang, Z. (2025) · Chinese Chemical Letters · doi:10.1016/j.cclet.2025.111089 · Cited by 1 · see citing works

Associations of stable psychological traits with multi-omic subtypes of Alzheimer’s dementia

Zammit, A. R., Yu, L., Poole, V. N., Tasaki, S., Vialle, R. A., Arfanakis, K., Schneider, J. A., Petyuk, V., Jager, P. L. D., Kaddurah‐Daouk, R., et al. (2026) · Translational Psychiatry · doi:10.1038/s41398-026-04195-z · Cited by 2 · see citing works

Immune Cell Deformability in Depressive Disorders: Longitudinal Associations Between Depression, Glucocorticoids and Cell DeformabilityPreprint

Walther, A., Kräter, M., Kirschbaum, C., Gao, W., Wekenborg, M., Penz, M. S., Rothe, N., Guck, J. R., Wittwer, L. D., & Eder, J. (2022) · medRxiv · doi:10.1101/2022.09.23.22280275 · Cited by 1 · see citing works

Longitudinal associations between depressive symptoms and cell deformability: do glucocorticoids play a role?

Eder, J., Kräter, M., Kirschbaum, C., Gao, W., Wekenborg, M., Penz, M., Rothe, N., Guck, J. R., Wittwer, L. D., & Walther, A. (2024) · European Archives of Psychiatry and Clinical Neuroscience · doi:10.1007/s00406-024-01902-z

Depressive and Anxiety Disorders and Urinary Biomarkers

Fujita, A., & Kato, K. (2024) · Springer eBooks · doi:10.1007/978-3-031-32035-4_18-1

The relevance of endoplasmic reticulum lumen and Anoctamin-8 for major depression: Results from a systems biology study

de Azevedo, S. C., Feiten, J. G., Fleck, M. P., & Caldieraro, M. A. (2025) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2025.01.039

Depressive and Anxiety Disorders and Urinary Biomarkers

Fujita, A., & Kato, K. (2025) · Springer eBooks · doi:10.1007/978-3-031-73368-0_18

Analysis of Genomic and Transcriptomic Data Revealed Key Genes and Processes in the Development of Major Depressive Disorder

Ivanov, S. M., Sukhachev, V. S., Tarasova, O. A., Lagunin, A. A., & Poroikov, V. (2025) · International Journal of Molecular Sciences · doi:10.3390/ijms26199557

Circulating lipids are associated with PTSD severity and predict symptomatic PTSD in a cohort of veterans and service members

Silvey, S. G., Cowart, A., Liu, J., Yue, Y., Allegood, J. C., Gill, J., Devoto, C., Horvath, P., & Valadka, A. B. (2026) · BMC Psychiatry · doi:10.1186/s12888-026-08535-7

Mass spectrometry approaches for monitoring therapeutic response in major depressive disorder

Romani, S. A. S., Silva, M. L. D., Ravaglia, G. B., Ferreira, P. C., Carvalho, C. D. D. A., Pereira, T. F. D., & Sussulini, A. (2025) · Bioanalysis · doi:10.1080/17576180.2025.2608564

Cross-sectional associations between CES-D scores and the salivary metabolome in nonclinical adults

Kubo, Y., Yamauchi, F., Goshima, N., Ohishi, M., Hasegawa, T., Soga, T., Ikeda, M., & Aoki, K. (2026) · Discover Mental Health · doi:10.1007/s44192-025-00363-7

Lipidomic remodeling of the brain and muscle in a zebrafish model of depression

Pinto, B., Santos, N., Domingues, P. M., Ferreira, H. B., Pinho, M., Melo, T., Domingues, I., & Domingues, M. R. (2026) · Journal of Affective Disorders · doi:10.1016/j.jad.2026.121630 · Cited by 1 · see citing works

The Association Between Serum Vitamin D and Lipid Levels in Patients With Depression: A Cross-Sectional Study

Yao, L., Lv, H., Nie, Z., Wang, W., Ma, S., Niu, Z., Wang, Y., Kang, L., Xiang, D., Yuan, W., et al. (2026) · ALPHA PSYCHIATRY · doi:10.31083/ap46265

Symptom-level transcriptome-wide associations of NMN-nominated KEGG pathways in major depression: a distributed endocytosis–hypersomnia signal, gene-weighted immune and motor cassettes, and limits of pathway-level polarity

Cheung, N. (2026) · BMC Psychiatry · doi:10.1186/s12888-026-08571-3

Targeted lipidomics showed altered serum phosphatidylcholine levels in fearful dogs

Sacchettino, L., Costanzo, M., Bianco, S., Veneruso, I., D’Argenio, V., Giuliano, V. O., Lombardi, P., Napolitano, F., & d’Angelo, D. (2026) · PLoS ONE · doi:10.1371/journal.pone.0356063

Adaptation of Lipid Profiling in Depression Disease and Treatment: A Critical Review

Pinto, B., Conde, T., Domingues, I., & Domingues, M. R. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23042032 · Cited by 51 · see citing works

48352 Mechanisms Underlying Lipidomic Changes in Major Depressive Disorder

Costa, A. P., van Dijr, M. T., Talati, A., Weissman, M. M., & McIntire, L. B. (2021) · Journal of Clinical and Translational Science · doi:10.1017/cts.2021.656 · Cited by 1 · see citing works

Serum lipidomic analysis for the discovery of biomarkers for major depressive disorder in drug-free patients

Kim, E. Y., Lee, J. W., Lee, M. Y., Kim, S. H., Mok, H. J., Ha, K., Ahn, Y. M., & Kim, K. P. (2018) · Psychiatry Research · doi:10.1016/j.psychres.2018.04.029 · Cited by 50 · see citing works

Deep Lipidomic Phenotyping Identifies Ceramide-Centered Lipotoxicity and Depletion of Plasmalogen-Carnitine Pathways in Major Depressive Disorder: Implications for Precision MedicinePreprint

Zhang, Y., Zhang, X., Niu, M., Luo, Y., Almulla, A. F., Maes, A., Li, J., Zhou, B., & Maes, M. (2026) · medRxiv · doi:10.64898/2026.02.01.26345328 · Cited by 3 · see citing works

Plasma lipidomics reveals potential lipid markers of major depressive disorder

Liu, X., Li, J., Zheng, P., Zhao, X., Zhou, C., Hu, C., Hou, X., Wang, H., Xie, P., & Xu, G. (2016) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-016-9768-5 · Cited by 148 · see citing works