Egan, Josephine M.

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

DIAGRAM Consortium, Dupuis, J., GIANT Consortium, Global BPgen Consortium, Anders Hamsten on behalf of Procardis Consortium, the MAGIC investigators, Langenberg, C., Prokopenko, I., Saxena, R., Soranzo, N., et al. (2010) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 2,166

Gut-expressed gustducin and taste receptors regulate secretion of glucagon-like peptide-1.

Jang, H.-J., Kokrashvili, Z., Theodorakis, M. J., Carlson, O. D., Kim, B.-J., Zhou, J., Kim, H. H., Xu, X., Chan, S. L., Juhaszova, M., et al. (2007) · Proceedings of the National Academy of Sciences

Biochemical Analysis and Sensing TechniquesDiabetes Treatment and Management

Cited by 995

The role of incretins in glucose homeostasis and diabetes treatment

Kim, W., & Egan, J. M. (2008) · Pharmacological Reviews

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 824

The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women

Harvie, M. N., Pegington, M., Mattson, M. P., Frystyk, J., Dillon, B., Evans, G., Cuzick, J., Jebb, S. A., Martin, B., Cutler, R. G., et al. (2011) · International Journal of Obesity

Dietary Effects on HealthNutritional Studies and Diet

Cited by 804

GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism

Li, Y., Perry, T., Kindy, M. S., Harvey, B. K., Tweedie, D., Holloway, H. W., Powers, K., Shen, H., Egan, J. M., Sambamurti, K., et al. (2009) · Proceedings of the National Academy of Sciences

Parkinson's Disease Mechanisms and TreatmentsNeuroprotection in Cerebral Ischemia

Cited by 589

Age-related changes in glucose metabolism, hyperglycemia, and cardiovascular risk

Chia, C. W., Egan, J. M., & Ferrucci, L. (2018) · Circulation Research

Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Treatment and Management

Cited by 454

Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice

Mitchell, S. J., Madrigal-Matute, J., Scheibye-Knudsen, M., Fang, E., Aon, M., González-Reyes, J. A., Cortassa, S., Kaushik, S., Gonzalez-Freire, M., Patel, B., et al. (2016) · Cell Metabolism

Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine

Cited by 451

The effect of intermittent energy and carbohydrate restriction v. daily energy restriction on weight loss and metabolic disease risk markers in overweight women

Harvie, M., Wright, C., Pegington, M., McMullan, D., Mitchell, E., Martin, B., Cutler, R. G., Evans, G., Whiteside, S., Maudsley, S., et al. (2013) · British Journal Of Nutrition

Dietary Effects on HealthDiet and metabolism studies

Cited by 431

Protection and Reversal of Excitotoxic Neuronal Damage by Glucagon-Like Peptide-1 and Exendin-4

Perry, T., Haughey, N. J., Mattson, M. P., Egan, J. M., & Greig, N. H. (2002) · The Journal of Pharmacology and Experimental Therapeutics

Alzheimer's disease research and treatmentsDiabetes Treatment and Management

Cited by 380

The physiology of endocrine systems with ageing

van den Beld, A. W., Kaufman, J.-M., Zillikens, M. C., Lamberts, S. W. J., Egan, J. M., & van der Lely, A. J. (2018) · The Lancet Diabetes & Endocrinology

Hormonal and reproductive studiesGrowth Hormone and Insulin-like Growth Factors

Cited by 349

Glucagon‐like peptide‐1 decreases endogenous amyloid‐β peptide (Aβ) levels and protects hippocampal neurons from death induced by Aβ and iron

Perry, T., Lahiri, D. K., Sambamurti, K., Chen, D., Mattson, M. P., Egan, J. M., & Greig, N. H. (2003) · Journal of Neuroscience Research

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 347

Plasma Adiponectin and Leptin Levels, Body Composition, and Glucose Utilization in Adult Women With Wide Ranges of Age and Obesity

Ryan, A. S., Berman, D. M., Nicklas, B. J., Sinha, M., Gingerich, R. L., Meneilly, G. S., Egan, J. M., & Elahi, D. (2003) · Diabetes Care

Adipokines, Inflammation, and Metabolic DiseasesRegulation of Appetite and Obesity

Cited by 279

Hyperglycemia Predicts Persistently Lower Muscle Strength With Aging

Kalyani, R. R., Metter, E. J., Egan, J., Golden, S. H., & Ferrucci, L. (2015) · Diabetes Care

Nutrition and Health in AgingMuscle Physiology and Disorders

Cited by 236

Sex-dependent metabolic, neuroendocrine, and cognitive responses to dietary energy restriction and excess

Martin, B., Pearson, M., Kebejian, L., Golden, E., Keselman, A., Bender, M., Carlson, O., Egan, J., Ladenheim, B., Cadet, J.-L., et al. (2007) · Endocrinology

Regulation of Appetite and ObesityDietary Effects on Health

Cited by 199

Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells

Bodogai, M., O’Connell, J., Kim, K., Kim, Y., Moritoh, K., Chen, C., Gusev, F., Vaughan, K., Shulzhenko, N., Mattison, J. A., et al. (2018) · Science Translational Medicine

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

Cited by 182

Glucose Intolerance, Insulin Resistance, and Pathological Features of Alzheimer Disease in the Baltimore Longitudinal Study of Aging

Thambisetty, M., Metter, E. J., Yang, A., Dolan, H., Marano, C., Zonderman, A. B., Troncoso, J. C., Zhou, Y., Wong, D. F., Ferrucci, L., et al. (2013) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 155

Quadriceps strength, quadriceps power, and gait speed in older U.S. adults with diabetes mellitus: results from the National Health and Nutrition Examination Survey, 1999–2002

Kalyani, R. R., Tra, Y., Yeh, H., Egan, J. M., Ferrucci, L., & Brancati, F. L. (2013) · Journal of the American Geriatrics Society

Nutrition and Health in AgingBalance, Gait, and Falls Prevention

Cited by 147

Cannabinoid type 2 receptors in dopamine neurons inhibits psychomotor behaviors, alters anxiety, depression and alcohol preference

Liu, Q.-R., Canseco-Alba, A., Zhang, H.-Y., Tagliaferro, P., Chung, M., Dennis, E., Sanabria, B., Schanz, N., Escosteguy-Neto, J. C., Ishiguro, H., et al. (2017) · Scientific Reports

Cannabis and Cannabinoid ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 147

Perinatal exercise improves glucose homeostasis in adult offspring

Carter, L. G., Lewis, K. N., Wilkerson, D. C., Tobia, C. M., Ngo Tenlep, S. Y., Shridas, P., Garcia-Cazarin, M. L., Wolff, G., Andrade, F. H., Charnigo, R. J., et al. (2012) · American Journal of Physiology-Endocrinology and Metabolism

Birth, Development, and HealthGestational Diabetes Research and Management

Cited by 118

RNA-Binding Protein HuD Controls Insulin Translation

Lee, E. K., Kim, W., Tominaga, K., Martindale, J. L., Yang, X., Subaran, S. S., Carlson, O. D., Mercken, E. M., Kulkarni, R. N., Akamatsu, W., et al. (2012) · Molecular Cell

Pancreatic function and diabetesRNA Research and Splicing

Cited by 108

Release of insulin produced by the choroid plexis is regulated by serotonergic signaling

Mazucanti, C. H., Liu, Q.-R., Lang, D., Huang, N., O’Connell, J. F., Camandola, S., & Egan, J. M. (2019) · JCI Insight

Cerebrospinal fluid and hydrocephalusPancreatic function and diabetes

Cited by 101

Incretins in obesity and diabetes

Chia, C. W., & Egan, J. M. (2020) · Annals of the New York Academy of Sciences

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 93

Disulfiram Treatment Normalizes Body Weight in Obese Mice

Bernier, M., Mitchell, S. J., Wahl, D., Diaz, A., Singh, A., Seo, W., Wang, M., Ali, A., Kaiser, T., Price, N. L., et al. (2020) · Cell Metabolism

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

Cited by 85

Insulin Resistance Is Associated With Reduced Mitochondrial Oxidative Capacity Measured by 31P-Magnetic Resonance Spectroscopy in Participants Without Diabetes From the Baltimore Longitudinal Study of Aging

Fabbri, E., Chia, C. W., Spencer, R. G., Fishbein, K. W., Reiter, D. A., Cameron, D., Zane, A. C., Moore, Z. A., Gonzalez-Freire, M., Zoli, M., et al. (2017) · Diabetes

Mitochondrial Function and PathologyDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 76