Mak, Tak W.

FOXO3a-dependent regulation of Pink1 (Park6) mediates survival signaling in response to cytokine deprivation

Mei, Y., Zhang, Y., Yamamoto, K., Xie, W., Mak, T. W., & You, H. (2009) · Proceedings of the National Academy of Sciences

FOXO transcription factor regulationRedox biology and oxidative stress

Cited by 172

Crucial Role of Interferon Consensus Sequence Binding Protein, but neither of Interferon Regulatory Factor 1 nor of Nitric Oxide Synthesis for Protection Against Murine Listeriosis

Fehr, T., Schoedon, G., Odermatt, B., Holtschke, T., Schneemann, M., Bachmann, M. F., Mak, T. W., Horak, I., & Zinkernagel, R. M. (1997) · The Journal of Experimental Medicine

interferon and immune responsesImmune responses and vaccinations

Cited by 162

Choline acetyltransferase-expressing T cells are required to control chronic viral infection

Cox, M. A., Duncan, G. S., Lin, G. H. Y., Steinberg, B. E., Yu, L. X., Brenner, D., Buckler, L. N., Elia, A. J., Wakeham, A. C., Nieman, B., et al. (2019) · Science

T-cell and B-cell ImmunologyVagus Nerve Stimulation Research

Cited by 155

Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia

Chen, Z., Shojaee, S., Buchner, M., Geng, H., Lee, J. W., Klemm, L., Titz, B., Graeber, T. G., Park, E., Tan, Y. X., et al. (2015) · Nature

Acute Lymphoblastic Leukemia researchT-cell and B-cell Immunology

Cited by 149

Mutant IDH is sufficient to initiate enchondromatosis in mice

Hirata, M., Sasaki, M., Cairns, R. A., Inoue, S., Puviindran, V., Li, W. Y., Snow, B. E., Jones, L. D., Wei, Q., Sato, S., et al. (2015) · Proceedings of the National Academy of Sciences

Bone Tumor Diagnosis and TreatmentsOsteoarthritis Treatment and Mechanisms

Cited by 115

Cloning and expression of an inducible lymphoid‐specific, protein tyrosine phosphatase (HePTPase)

Zanke, B., Suzuki, H., Kishihara, K., Mizzen, L., Minden, M., Pawson, A., & Mak, T. W. (1992) · European Journal of Immunology

Protein Tyrosine PhosphatasesT-cell and B-cell Immunology

Cited by 101

Disruption of the Lcn2 gene in mice suppresses primary mammary tumor formation but does not decrease lung metastasis

Berger, T., Cheung, C. C., Elia, A. J., & Mak, T. W. (2010) · Proceedings of the National Academy of Sciences

Protease and Inhibitor MechanismsMechanisms of cancer metastasis

Cited by 96

2-HG Inhibits Necroptosis by Stimulating DNMT1-Dependent Hypermethylation of the RIP3 Promoter

Yang, Z., Jiang, B., Wang, Y., Ni, H., Zhang, J., Xia, J., Shi, M., Hung, L.-M., Ruan, J., Mak, T. W., et al. (2017) · Cell Reports

Epigenetics and DNA MethylationGlioma Diagnosis and Treatment

Cited by 78

Tumor-specific cholinergic CD4+ T lymphocytes guide immunosurveillance of hepatocellular carcinoma

Zheng, C., Snow, B. E., Elia, A. J., Nechanitzky, R., Dominguez-Brauer, C., Liu, S., Tong, Y., Cox, M. A., Focaccia, E., Wakeham, A. C., et al. (2023) · Nature Cancer

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 75

Mutant IDH inhibitors induce lineage differentiation in IDH-mutant oligodendroglioma

Spitzer, A., Gritsch, S., Nomura, M., Jucht, A., Fortin, J., Raviram, R., Weisman, H. R., Gonzalez Castro, L. N., Druck, N., Chanoch-Myers, R., et al. (2024) · Cancer Cell

Glioma Diagnosis and TreatmentAcute Myeloid Leukemia Research

Cited by 69

Lipocalin 2 Regulates Inflammation during Pulmonary Mycobacterial Infections

Guglani, L., Gopal, R., Rangel-Moreno, J., Junecko, B. F., Lin, Y., Berger, T., Mak, T. W., Alcorn, J. F., Randall, T. D., Reinhart, T. A., et al. (2012) · PLoS ONE

Tuberculosis Research and EpidemiologyImmune Response and Inflammation

Cited by 68

Tim-3 adaptor protein Bat3 is a molecular checkpoint of T cell terminal differentiation and exhaustion

Zhu, C., Dixon, K. O., Newcomer, K., Gu, G., Xiao, S., Zaghouani, S., Schramm, M. A., Wang, C., Zhang, H., Goto, K., et al. (2021) · Science Advances

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 40

Cooperative interaction between the DNA-binding domains of PU.1 and IRF4

Yee, A. A., Yin, P., Siderovski, D. P., Mak, T. W., Litchfield, D. W., & Arrowsmith, C. H. (1998) · Journal of Molecular Biology

Genomics and Chromatin Dynamicsinterferon and immune responses

Cited by 38

IDH1 Mutation Promotes Tumorigenesis by Inhibiting JNK Activation and Apoptosis Induced by Serum Starvation

Jiang, B., Zhang, J., Xia, J., Zhao, W., Wu, Y., Shi, M., Luo, L., Zhou, H., Chen, A., Ma, H., et al. (2017) · Cell Reports

Glioma Diagnosis and TreatmentCancer, Hypoxia, and Metabolism

Cited by 33

B cell-derived acetylcholine promotes liver regeneration by regulating Kupffer cell and hepatic CD8+ T cell function

Modares, N. F., Hendrikse, L. D., Smith, L. K., Paul, M. S., Haight, J., Luo, P., Liu, S., Fortin, J., Tong, F. K., Wakeham, A. C., et al. (2025) · Immunity

Liver physiology and pathologyWound Healing and Treatments

Cited by 29