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DoOR 2.0 - Comprehensive Mapping of Drosophila melanogaster Odorant Responses

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Chondrosarcoma: A Rare Misfortune in Aging Human Cartilage? The Role of Stem and Progenitor Cells in Proliferation, Malignant Degeneration and Therapeutic Resistance

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FGFR3 Deficiency Causes Multiple Chondroma-like Lesions by Upregulating Hedgehog Signaling

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Inhibitors of Mutant Isocitrate Dehydrogenases 1 and 2 (mIDH1/2): An Update and Perspective

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Is the IDH Mutation a Good Target for Chondrosarcoma Treatment?

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IDH1 Mutation Promotes Tumorigenesis by Inhibiting JNK Activation and Apoptosis Induced by Serum Starvation

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IDH1 deficiency attenuates gluconeogenesis in mouse liver by impairing amino acid utilization

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Molecular Pathology of Bone Tumors

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Enigmas of IDH mutations in hematology/oncology

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A genetic model for central chondrosarcoma evolution correlates with patient outcome

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Metabolic Pathways and Targets in Chondrosarcoma

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IDH Mutations in Chondrosarcoma: Case Closed or Not?

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Hedgehog activation promotes osteogenic fates of growth plate resting zone chondrocytes through transient clonal competency

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Mutant IDH and non-mutant chondrosarcomas display distinct cellular metabolomes

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Idh1 mutations contribute to the development of T-cell malignancies in genetically engineered mice

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Prognostic impact of IDH mutations in chondrosarcoma

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Mutation-driven epigenetic alterations as a defining hallmark of central cartilaginous tumours, giant cell tumour of bone and chondroblastoma

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Phase I Study of the Mutant IDH1 Inhibitor Ivosidenib: Long-term Safety and Clinical Activity in Patients with Conventional Chondrosarcoma

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Embedding information flows within ecological networks

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Distinct Roles of Glutamine Metabolism in Benign and Malignant Cartilage Tumors With IDH Mutations

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Mutant IDH regulates glycogen metabolism from early cartilage development to malignant chondrosarcoma formation

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Fire and water: Tumor cell adaptation to metabolic conditions

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Chondrosarcoma: New Molecular Insights, Challenges in Near-Patient Preclinical Modeling, and Therapeutic Approaches

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The oncometabolite R-2-hydroxyglutarate dysregulates the differentiation of human mesenchymal stromal cells via inducing DNA hypermethylation

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Essential role of the metabolite α-ketoglutarate in bone tissue and bone-related diseases

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Are IDH1 R132 Mutations Associated With Poor Prognosis in Patients With Chondrosarcoma of the Bone?

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Intracellular cholesterol biosynthesis in enchondroma and chondrosarcoma

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Hedgehog signaling orchestrates cartilage-to-bone transition independently of Smoothened

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Advances in the pathogenesis and possible treatments for multiple hereditary exostoses from the 2016 international MHE conference

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Maffucci syndrome complicated by three different central nervous system tumors sharing an IDH1 R132C mutation: case report

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Mutation of IDH1 aggravates the fatty acid‑induced oxidative stress in HCT116 cells by affecting the mitochondrial respiratory chain

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IDH1 immunohistochemistry reactivity and mosaic IDH1 or IDH2 somatic mutations in pediatric sporadic enchondroma and enchondromatosis

Saïji, E., Gumy‐Pause, F., Lascombes, P., Biderbost, C. C., Marq, N. L., Berczy, M., Merlini, L., & Rougemont, A. (2019) · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin · doi:10.1007/s00428-019-02606-9 · Cited by 15 · see citing works

Genetic drivers and cells of origin in sarcomagenesis

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Inhibitor potency varies widely among tumor-relevant human isocitrate dehydrogenase 1 mutants

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A single-cell atlas of conventional central chondrosarcoma reveals the role of endoplasmic reticulum stress in malignant transformation

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Enchondromatosis and Growth Plate Development

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IDH1/2 Mutations in Cancer: Unifying Insights and Unlocking Therapeutic Potential for Chondrosarcoma

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DDIT3 regulates cementoblast mineralization by isocitrate dehydrogenase 1 through nuclear factor‐κB pathway

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Tumor Syndromes That Include Bone Tumors

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Next Generation Sequencing-Based Transcriptome Predicts Bevacizumab Efficacy in Combination with Temozolomide in Glioblastoma

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Chemosensory Coding inDrosophilaSingle SensillaPreprint

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Isocitrate Dehydrogenase Mutations in Human Cancers: Physiopathologic Mechanisms and Therapeutic Targeting

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IDH1-mutated transgenic zebrafish lines: An in-vivo model for drug screening and functional analysis

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Loss of IDH1 and IDH2 mutations during the evolution of metastatic chondrosarcoma

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IDH1 mutated acute myeloid leukemia in a child with metaphyseal chondromatosis with D-2-hydroxyglutaric aciduria

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IDH mutations in G2-3 conventional central bone chondrosarcoma: a mono institutional experience

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Loss of the mitochondrial carrier, SLC25A1, during embryogenesis induces a unique senescence program controlled by p53Preprint

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Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms

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A Genetic Model for Central Chondrosarcoma Evolution Correlates with Patient OutcomePreprint

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Protein Phosphatase 1 Regulatory Subunit 3C integrates cholesterol metabolism and isocitrate dehydrogenase in chondrocytes and neoplasia

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A Case of Ollier's Disease with P53 Mutation Positive and IDH1 (R132H) Negative Multicentric Gliomas

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Targeting epigenetic aberrations of sarcoma in CRISPR era

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Water Networks and Correlated Motions in Mutant Isocitrate Dehydrogenase 1 (IDH1) Are Critical for Allosteric Inhibitor Binding and Activity

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Inactivation of Lkb1 in postnatal chondrocytes leads to epiphyseal growth‐plate abnormalities and promotes enchondroma‐like formation

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Catalytically distinct metabolic enzyme isocitrate dehydrogenase 1 mutants tune phenotype severity in tumor models

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Dnmt1 determines bone length by regulating energy metabolism of growth plate chondrocytes

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Status of IDH mutations in chondrosarcoma of the jaws

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Effect of Nano-Formulated Agrochemicals on Rhizospheric Communities in Millets

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Fatty Acid Origin of Insect Pheromones

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Targeted Therapy of IDH1-Mutated Tumors

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Single cell analysis of Idh mutant growth plates identifies cell populations responsible for longitudinal bone growth and enchondroma formation

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Chondrosarcoma

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Growth plate resting zone chondrocytes acquire transient clonal competency upon Hedgehog activation and efficiently transform into trabecular bone osteoblastsPreprint

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Mutant IDH is sufficient to initiate enchondromatosis in mice 01.pdf

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Abstract 864: Mutant IDH1 is essential for chondrosarcoma growth

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IDH mosaicism in enchondromatosis syndromes

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IDH1 immunohistochemistry reactivity and mosaic IDH1 or IDH2 somatic mutations in pediatric sporadic enchondroma and enchondromatosis

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<i>IDH1</i> and <i>IDH2</i> mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours

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