Luedde, Tom

Direct Reprogramming of Hepatic Myofibroblasts into Hepatocytes In Vivo Attenuates Liver Fibrosis

Song, G., Pacher, M., Balakrishnan, A., Yuan, Q., Tsay, H.-C., Yang, D., Reetz, J., Brandes, S., Dai, Z., Pützer, B. M., et al. (2016) · Cell Stem Cell

Liver physiology and pathologyPluripotent Stem Cells Research

Cited by 208

Chemokine receptor CCR6-dependent accumulation of γδ T cells in injured liver restricts hepatic inflammation and fibrosis

Hammerich, L., Bangen, J. M., Govaere, O., Zimmermann, H. W., Gassler, N., Huss, S., Liedtke, C., Prinz, I., Lira, S. A., Luedde, T., et al. (2014) · Hepatology

Liver physiology and pathologyLiver Diseases and Immunity

Cited by 190

In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation

Jensen, B.-E. O., Knops, E., Cords, L., Lübke, N., Salgado, M., Busman-Sahay, K., Estes, J. D., Huyveneers, L. E. P., Perdomo-Celis, F., Wittner, M., et al. (2023) · Nature Medicine

HIV Research and TreatmentVirus-based gene therapy research

Cited by 158

RIPK1 Suppresses a TRAF2-Dependent Pathway to Liver Cancer

Schneider, A. T., Gautheron, J., Feoktistova, M., Roderburg, C., Loosen, S. H., Roy, S., Benz, F., Schemmer, P., Büchler, M. W., Nachbur, U., et al. (2017) · Cancer Cell

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 155

CD40-mediated immune cell activation enhances response to anti-PD-1 in murine intrahepatic cholangiocarcinoma

Diggs, L. P., Ruf, B., Ma, C., Heinrich, B., Cui, L., Zhang, Q., McVey, J. C., Wabitsch, S., Heinrich, S., Rosato, U., et al. (2021) · Journal of Hepatology

Cholangiocarcinoma and Gallbladder Cancer StudiesCancer Immunotherapy and Biomarkers

Cited by 151

Fluorescent cell-traceable dexamethasone-loaded liposomes for the treatment of inflammatory liver diseases

Bartneck, M., Scheyda, K. M., Warzecha, K. T., Rizzo, L. Y., Hittatiya, K., Luedde, T., Storm, G., Trautwein, C., Lammers, T., & Tacke, F. (2015) · Biomaterials

Nanoparticle-Based Drug DeliveryLiver physiology and pathology

Cited by 141

Development and validation of deep learning classifiers to detect Epstein-Barr virus and microsatellite instability status in gastric cancer: a retrospective multicentre cohort study

Muti, H. S., Heij, L. R., Keller, G., Kohlruss, M., Langer, R., Dislich, B., Cheong, J.-H., Kim, Y.-W., Kim, H., Kook, M.-C., et al. (2021) · The Lancet Digital Health

AI in cancer detectionGastric Cancer Management and Outcomes

Cited by 126

Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis

Reich, M., Spomer, L., Klindt, C., Fuchs, K., Stindt, J., Deutschmann, K., Höhne, J., Liaskou, E., Hov, J. R., Karlsen, T. H., et al. (2021) · Journal of Hepatology

Liver Diseases and ImmunityDrug Transport and Resistance Mechanisms

Cited by 121

Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling

Kotsiliti, E., Leone, V., Schuehle, S., Govaere, O., Li, H., Wolf, M. J., Horvatic, H., Bierwirth, S., Hundertmark, J., Inverso, D., et al. (2023) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 108

Histidine‐rich glycoprotein promotes macrophage activation and inflammation in chronic liver disease

Bartneck, M., Fech, V., Ehling, J., Govaere, O., Warzecha, K. T., Hittatiya, K., Vucur, M., Gautheron, J., Luedde, T., Trautwein, C., et al. (2016) · Hepatology

Liver physiology and pathologyImmune cells in cancer

Cited by 101

TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation

Labiano, I., Agirre-Lizaso, A., Olaizola, P., Echebarria, A., Huici-Izagirre, M., Olaizola, I., Esparza-Baquer, A., Sharif, O., Hijona, E., Milkiewicz, P., et al. (2022) · Journal of Hepatology

Liver Diseases and ImmunityLiver physiology and pathology

Cited by 78

Skeletal Muscle Composition Predicts Outcome in Critically Ill Patients

Loosen, S. H., Schulze-Hagen, M., Püngel, T., Bündgens, L., Wirtz, T., Kather, J. N., Vucur, M., Paffenholz, P., Demir, M., Bruners, P., et al. (2020) · Critical Care Explorations

Nutrition and Health in AgingClinical Nutrition and Gastroenterology

Cited by 58

miR-1224 inhibits cell proliferation in acute liver failure by targeting the antiapoptotic gene Nfib

Roy, S., Bantel, H., Wandrer, F., Schneider, A. T., Gautheron, J., Vucur, M., Tacke, F., Trautwein, C., Luedde, T., & Roderburg, C. (2017) · Journal of Hepatology

MicroRNA in disease regulationLiver physiology and pathology

Cited by 56

Roles of CCR2 and CCR5 for hepatic macrophage polarization in mice with liver parenchymal cell-specific NEMO deletion

Bartneck, M., Koppe, C., Fech, V., Warzecha, K. T., Kohlhepp, M., Huss, S., Weiskirchen, R., Trautwein, C., Luedde, T., & Tacke, F. (2021) · Cellular and Molecular Gastroenterology and Hepatology

Liver physiology and pathologyChemokine receptors and signaling

Cited by 44

Liver fibrosis affects the targeting properties of drug delivery systems to macrophage subsets in vivo

Ergen, C., Niemietz, P. M., Heymann, F., Baues, M., Gremse, F., Pola, R., van Bloois, L., Storm, G., Kiessling, F., Trautwein, C., et al. (2019) · Biomaterials

Nanoparticle-Based Drug DeliveryLiver physiology and pathology

Cited by 27

Telomere Shortening in Peripheral Leukocytes Is Associated With Poor Survival in Cancer Patients Treated With Immune Checkpoint Inhibitor Therapy

Rolles, B., Gorgulho, J., Tometten, M., Roderburg, C., Vieri, M., Abels, A., Vucur, M., Heymann, F., Tacke, F., Brümmendorf, T. H., et al. (2021) · Frontiers in Oncology

Telomeres, Telomerase, and SenescenceCancer Immunotherapy and Biomarkers

Cited by 12

Mechanically stimulated hepatic stellate cells release WNT5A that triggers apoptosis in HCC cell lines

Vollmuth, S., Schweigert, A., Reichert, D., Luedde, T., & Kordes, C. (2022) · Zeitschrift für Gastroenterologie

Wnt/β-catenin signaling in development and cancerLiver physiology and pathology

Cited by 0