Trimbuch, Thorsten

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function

Piwecka, M., Glažar, P., Hernandez-Miranda, L. R., Memczak, S., Wolf, S. A., Rybak-Wolf, A., Filipchyk, A., Klironomos, F., Cerda Jara, C. A., Fenske, P., et al. (2017) · Science

Circular RNAs in diseasesRNA Research and Splicing

Cited by 1,210

An unconventional role for miRNA: let-7 activates toll-like receptor 7 and causes neurodegeneration

Lehmann, S. M., Krüger, C., Park, B., Derkow, K., Rosenberger, K., Baumgart, J., Trimbuch, T., Eom, G., Hinz, M., Kaul, D., et al. (2012) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsMicroRNA in disease regulation

Cited by 786

Clathrin regenerates synaptic vesicles from endosomes

Watanabe, S., Trimbuch, T., Camacho-Pérez, M., Rost, B. R., Brokowski, B., Söhl-Kielczynski, B., Felies, A., Davis, M. W., Rosenmund, C., & Jorgensen, E. M. (2014) · Nature

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 333

Human endogenous retrovirus HERV-K(HML-2) RNA causes neurodegeneration through Toll-like receptors

Dembny, P., Newman, A. G., Singh, M., Hinz, M., Szczepek, M., Krüger, C., Adalbert, R., Dzaye, O., Trimbuch, T., Wallach, T., et al. (2020) · JCI Insight

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 134

Synaptojanin and Endophilin Mediate Neck Formation during Ultrafast Endocytosis

Watanabe, S., Mamer, L. E., Raychaudhuri, S., Luvsanjav, D., Eisen, J., Trimbuch, T., Söhl-Kielczynski, B., Fenske, P., Milosevic, I., Rosenmund, C., et al. (2018) · Neuron

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 131

Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN

Xu, J., Camacho, M., Xu, Y., Esser, V., Liu, X., Trimbuch, T., Pan, Y.-Z., Ma, C., Tomchick, D. R., Rosenmund, C., et al. (2017) · eLife

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 119

Dynamin is primed at endocytic sites for ultrafast endocytosis

Imoto, Y., Raychaudhuri, S., Fenske, P., Sandoval, E., Itoh, K., Blumrich, E.-M., Mamer, L., Zarebidaki, F., Söhl-Kielczynski, B., Trimbuch, T., et al. (2021) · Neuron

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 109

Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming

Camacho, M., Basu, J., Trimbuch, T., Chang, S., Pulido-Lozano, C., Chang, S.-S., Duluvova, I., Abo-Rady, M., Rizo, J., & Rosenmund, C. (2017) · Nature Communications

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 95

Disentangling the roles of RIM and Munc13 in synaptic vesicle localization and neurotransmission

Zarebidaki, F., Camacho, M., Brockmann, M. M., Trimbuch, T., Herman, M. A., & Rosenmund, C. (2020) · The Journal of Neuroscience

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 37

Neurotransmitter release is triggered by a calcium-induced rearrangement in the Synaptotagmin-1/SNARE complex primary interface

Toulmé, E., Salazar Lázaro, A., Trimbuch, T., Rizo, J., & Rosenmund, C. (2024) · Proceedings of the National Academy of Sciences

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 27