Hruban, Ralph H.

Multicomponent analysis of the pancreatic adenocarcinoma progression model using a pancreatic intraepithelial neoplasia tissue microarray

Maitra, A., Adsay, N. V., Argani, P., Iacobuzio-Donahue, C., De Marzo, A., Cameron, J. L., Yeo, C. J., & Hruban, R. H. (2003) · Modern Pathology

Pancreatic and Hepatic Oncology ResearchCholangiocarcinoma and Gallbladder Cancer Studies

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Risk of Neoplastic Progression in Individuals at High Risk for Pancreatic Cancer Undergoing Long-term Surveillance

Canto, M. I., Almario, J. A., Schulick, R. D., Yeo, C. J., Klein, A., Blackford, A., Shin, E. J., Sanyal, A., Yenokyan, G., Lennon, A. M., et al. (2018) · Gastroenterology

Pancreatic and Hepatic Oncology ResearchPancreatitis Pathology and Treatment

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Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer

Makohon-Moore, A. P., Zhang, M., Reiter, J. G., Bozic, I., Allen, B., Kundu, D., Chatterjee, K., Wong, F., Jiao, Y., Kohutek, Z. A., et al. (2017) · Nature Genetics

Cancer Genomics and DiagnosticsPancreatic and Hepatic Oncology Research

Cited by 403

KrasG12D and Smad4/Dpc4 Haploinsufficiency Cooperate to Induce Mucinous Cystic Neoplasms and Invasive Adenocarcinoma of the Pancreas

Izeradjene, K., Combs, C., Best, M., Gopinathan, A., Wagner, A., Grady, W. M., Deng, C.-X., Hruban, R. H., Adsay, N. V., Tuveson, D. A., et al. (2007) · Cancer Cell

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

Cited by 379

Genetic progression in the pancreatic ducts

Hruban, R. H., Wilentz, R. E., & Kern, S. E. (2000) · The American Journal of Pathology

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

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Serous cystic neoplasm of the pancreas: a multinational study of 2622 patients under the auspices of the International Association of Pancreatology and European Pancreatic Club (European Study Group on Cystic Tumors of the Pancreas)

Jais, B., Rebours, V, Malleo, G., Salvia, R., Fontana, M., Maggino, L., Bassi, C., Manfredi, R., Moran, R., Lennon, A. M., et al. (2016) · Gut

Pancreatic and Hepatic Oncology ResearchNeuroendocrine Tumor Research Advances

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SMAD4 Gene Mutations Are Associated with Poor Prognosis in Pancreatic Cancer

Blackford, A., Serrano, O. K., Wolfgang, C. L., Parmigiani, G., Jones, S., Zhang, X., Parsons, D. W., Lin, J. C.-H., Leary, R. J., Eshleman, J. R., et al. (2009) · Clinical Cancer Research

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

Cited by 371

Telomere Shortening Is Nearly Universal in Pancreatic Intraepithelial Neoplasia

van Heek, N. T., Meeker, A. K., Kern, S. E., Yeo, C. J., Lillemoe, K. D., Cameron, J. L., Offerhaus, G. J. A., Hicks, J. L., Wilentz, R. E., Goggins, M. G., et al. (2002) · The American Journal of Pathology

Telomeres, Telomerase, and SenescencePancreatic and Hepatic Oncology Research

Cited by 363

Whole Genome Sequencing Defines the Genetic Heterogeneity of Familial Pancreatic Cancer

Roberts, N. J., Norris, A. L., Petersen, G. M., Bondy, M. L., Brand, R., Gallinger, S., Kurtz, R. C., Olson, S. H., Rustgi, A. K., Schwartz, A. G., et al. (2016) · Cancer Discovery

Pancreatic and Hepatic Oncology ResearchGenetic factors in colorectal cancer

Cited by 361

Intraductal papillary mucinous neoplasms of the pancreas: an increasingly recognized clinicopathologic entity

Sohn, T. A., Yeo, C. J., Cameron, J. L., Iacobuzio-Donahue, C. A., Hruban, R. H., & Lillemoe, K. D. (2001) · Annals of Surgery

Pancreatic and Hepatic Oncology ResearchNeuroendocrine Tumor Research Advances

Cited by 311

BRCA1, BRCA2, PALB2, and CDKN2A mutations in familial pancreatic cancer: a PACGENE study

Zhen, D. B., Rabe, K. G., Gallinger, S., Syngal, S., Schwartz, A. G., Goggins, M. G., Hruban, R. H., Cote, M. L., McWilliams, R. R., Roberts, N. J., et al. (2015) · Genetics in Medicine

BRCA gene mutations in cancerPancreatic and Hepatic Oncology Research

Cited by 295

Disruption of chromatin folding domains by somatic genomic rearrangements in human cancer

Akdemir, K. C., Le, V. T., Chandran, S., Li, Y., Verhaak, R. G., Beroukhim, R., Campbell, P. J., Chin, L., Dixon, J. R., Futreal, P. A., et al. (2020) · Nature Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

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Clinical Significance of the Genetic Landscape of Pancreatic Cancer and Implications for Identification of Potential Long-term Survivors

Yachida, S., White, C. M., Naito, Y., Zhong, Y., Brosnan, J. A., Macgregor-Das, A. M., Morgan, R. A., Saunders, T., Laheru, D. A., Herman, J. M., et al. (2012) · Clinical Cancer Research

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

Cited by 280

Recent Trends in the Incidence and Survival of Stage 1A Pancreatic Cancer: A Surveillance, Epidemiology, and End Results Analysis

Blackford, A. L., Canto, M. I., Klein, A. P., Hruban, R. H., & Goggins, M. (2020) · JNCI: Journal of the National Cancer Institute

Pancreatic and Hepatic Oncology ResearchGlobal Cancer Incidence and Screening

Cited by 270

Molecular genetics of pancreatic intraepithelial neoplasia

Feldmann, G., Beaty, R., Hruban, R. H., & Maitra, A. (2007) · Journal of Hepato-Biliary-Pancreatic Surgery

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

Cited by 269

CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan

Vennin, C., Mélénec, P., Rouet, R., Nobis, M., Cazet, A. S., Murphy, K. J., Herrmann, D., Reed, D. A., Lucas, M. C., Warren, S. C., et al. (2019) · Nature Communications

Pancreatic and Hepatic Oncology ResearchCancer Cells and Metastasis

Cited by 268

Importance of Age of Onset in Pancreatic Cancer Kindreds

Brune, K. A., Lau, B., Palmisano, E., Canto, M., Goggins, M. G., Hruban, R. H., & Klein, A. P. (2010) · JNCI Journal of the National Cancer Institute

Pancreatic and Hepatic Oncology ResearchGenetic factors in colorectal cancer

Cited by 257

TERT Promoter Mutations Occur Early in Urothelial Neoplasia and Are Biomarkers of Early Disease and Disease Recurrence in Urine

Kinde, I., Munari, E., Faraj, S. F., Hruban, R. H., Schoenberg, M., Bivalacqua, T., Allaf, M., Springer, S., Wang, Y., Diaz, L. A., et al. (2013) · Cancer Research

Bladder and Urothelial Cancer TreatmentsUrinary and Genital Oncology Studies

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The Multicenter Cancer of Pancreas Screening Study: Impact on Stage and Survival

Dbouk, M., Katona, B. W., Brand, R. E., Chak, A., Syngal, S., Farrell, J. J., Kastrinos, F., Stoffel, E. M., Blackford, A. L., Rustgi, A. K., et al. (2022) · Journal of Clinical Oncology

Pancreatic and Hepatic Oncology ResearchGlobal Cancer Incidence and Screening

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CODA: quantitative 3D reconstruction of large tissues at cellular resolution

Kiemen, A. L., Braxton, A. M., Grahn, M. P., Han, K. S., Babu, J. M., Reichel, R., Jiang, A. C., Kim, B., Hsu, J., Amoa, F., et al. (2022) · Nature Methods

Cell Image Analysis TechniquesAI in cancer detection

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A multimodality test to guide the management of patients with a pancreatic cyst

Springer, S., Masica, D. L., Dal Molin, M., Douville, C., Thoburn, C. J., Afsari, B., Li, L., Cohen, J. D., Thompson, E., Allen, P. J., et al. (2019) · Science Translational Medicine

Pancreatic and Hepatic Oncology ResearchPancreatitis Pathology and Treatment

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Utility of CT Radiomics Features in Differentiation of Pancreatic Ductal Adenocarcinoma From Normal Pancreatic Tissue.

Chu, L. C., Park, S., Kawamoto, S., Fouladi, D. F., Shayesteh, S., Zinreich, E. S., Graves, J. S., Horton, K. M., Hruban, R. H., Yuille, A. L., et al. (2019) · American Journal of Roentgenology

Radiomics and Machine Learning in Medical ImagingPancreatic and Hepatic Oncology Research

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Cystic precursors to invasive pancreatic cancer

Matthaei, H., Schulick, R. D., Hruban, R. H., & Maitra, A. (2011) · Nature Reviews Gastroenterology & Hepatology

Pancreatic and Hepatic Oncology ResearchPancreatitis Pathology and Treatment

Cited by 193

Mutant TP53 in Duodenal Samples of Pancreatic Juice From Patients With Pancreatic Cancer or High-Grade Dysplasia

Kanda, M., Sadakari, Y., Borges, M., Topazian, M., Farrell, J., Syngal, S., Lee, J., Kamel, I., Lennon, A. M., Knight, S., et al. (2013) · Clinical Gastroenterology and Hepatology

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

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